SUSD4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045087Biological processinnate immune response
GO_0045957Biological processnegative regulation of complement activation, alternative pathway
GO_0006958Biological processcomplement activation, classical pathway
GO_0030449Biological processregulation of complement activation
GO_0045959Biological processnegative regulation of complement activation, classical pathway
GO_0005576Cellular componentextracellular region
GO_0016020Cellular componentmembrane

IV. Literature review

[source]
Gene nameSUSD4
Protein nameSushi domain-containing protein 4
SUSD4 protein
Sushi domain containing 4
SynonymsUNQ196/PRO222
DescriptionFUNCTION: Acts as a complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. .

AccessionsA5YM74
ENST00000343846.7 [Q5VX71-1]
ENST00000366878.9 [Q5VX71-1]
ENST00000344029.6 [Q5VX71-3]
V9GYN8
Q5VX71
ENST00000681285.1
ENST00000608996.5
ENST00000679807.1
ENST00000680429.1
V9GZ49
ENST00000679975.1
A0A7P0T864
A0A7P0Z409
A0A7P0T8V7
ENST00000681404.1
ENST00000681305.1 [Q5VX71-1]
ENST00000484758.6
ENST00000681669.1 [Q5VX71-1]
A0A7P0Z457
ENST00000494793.6
B7Z369