ANKRD17 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	30 studies	47% ± 17%	Explore
astrocyte	19 studies	49% ± 19%	Explore
fibroblast	17 studies	38% ± 15%	Explore
oligodendrocyte	16 studies	48% ± 15%	Explore
oligodendrocyte precursor cell	16 studies	49% ± 19%	Explore
microglial cell	16 studies	52% ± 15%	Explore
macrophage	14 studies	43% ± 19%	Explore
glutamatergic neuron	13 studies	63% ± 24%	Explore
pericyte	12 studies	42% ± 16%	Explore
basal cell	11 studies	37% ± 21%	Explore
smooth muscle cell	11 studies	37% ± 12%	Explore
GABAergic neuron	11 studies	61% ± 21%	Explore
endothelial cell of lymphatic vessel	10 studies	40% ± 16%	Explore
epithelial cell	10 studies	46% ± 21%	Explore
myeloid cell	10 studies	32% ± 14%	Explore
ciliated cell	10 studies	28% ± 13%	Explore
mast cell	10 studies	32% ± 13%	Explore
adipocyte	9 studies	61% ± 17%	Explore
B cell	8 studies	30% ± 13%	Explore
T cell	8 studies	32% ± 11%	Explore
natural killer cell	7 studies	27% ± 11%	Explore
neuron	7 studies	54% ± 20%	Explore
interneuron	7 studies	61% ± 25%	Explore
club cell	7 studies	38% ± 17%	Explore
retinal cone cell	7 studies	52% ± 26%	Explore
dendritic cell	7 studies	36% ± 9%	Explore
type I pneumocyte	7 studies	40% ± 16%	Explore
respiratory goblet cell	6 studies	38% ± 18%	Explore
CD4-positive, alpha-beta T cell	6 studies	24% ± 7%	Explore
retinal ganglion cell	6 studies	49% ± 21%	Explore
amacrine cell	6 studies	38% ± 18%	Explore
retina horizontal cell	6 studies	38% ± 23%	Explore
retinal rod cell	6 studies	47% ± 24%	Explore
CD8-positive, alpha-beta T cell	6 studies	22% ± 7%	Explore
endothelial cell of artery	6 studies	24% ± 7%	Explore
mesothelial cell	6 studies	39% ± 14%	Explore
vein endothelial cell	6 studies	32% ± 15%	Explore
type II pneumocyte	6 studies	44% ± 13%	Explore
hepatocyte	5 studies	56% ± 27%	Explore
cardiac muscle cell	5 studies	61% ± 17%	Explore
endothelial cell of vascular tree	5 studies	33% ± 18%	Explore
monocyte	5 studies	46% ± 8%	Explore
goblet cell	5 studies	36% ± 27%	Explore
secretory cell	4 studies	21% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	25% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	23% ± 7%	Explore
granule cell	4 studies	54% ± 8%	Explore
plasma cell	4 studies	43% ± 7%	Explore
brush cell	4 studies	26% ± 6%	Explore
retinal pigment epithelial cell	4 studies	51% ± 25%	Explore
lymphocyte	4 studies	36% ± 11%	Explore
Mueller cell	4 studies	45% ± 19%	Explore
capillary endothelial cell	4 studies	35% ± 9%	Explore
connective tissue cell	4 studies	34% ± 17%	Explore
leukocyte	4 studies	44% ± 16%	Explore
myofibroblast cell	4 studies	35% ± 20%	Explore
ionocyte	3 studies	28% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	22% ± 9%	Explore
classical monocyte	3 studies	21% ± 3%	Explore
mature NK T cell	3 studies	29% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	27% ± 8%	Explore
non-classical monocyte	3 studies	22% ± 4%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	55% ± 1%	Explore
GABAergic interneuron	3 studies	64% ± 2%	Explore
glial cell	3 studies	35% ± 9%	Explore
progenitor cell	3 studies	44% ± 9%	Explore
squamous epithelial cell	3 studies	34% ± 21%	Explore
mononuclear phagocyte	3 studies	36% ± 13%	Explore
mucosal invariant T cell	3 studies	25% ± 7%	Explore
retinal bipolar neuron	3 studies	40% ± 21%	Explore
GABAergic amacrine cell	3 studies	55% ± 14%	Explore
OFF-bipolar cell	3 studies	43% ± 19%	Explore
ON-bipolar cell	3 studies	47% ± 22%	Explore
glycinergic amacrine cell	3 studies	46% ± 11%	Explore
cholangiocyte	3 studies	64% ± 11%	Explore
abnormal cell	3 studies	41% ± 24%	Explore
neural progenitor cell	3 studies	49% ± 20%	Explore
ependymal cell	3 studies	55% ± 17%	Explore
enteroendocrine cell	3 studies	23% ± 4%	Explore
alveolar macrophage	3 studies	55% ± 11%	Explore
muscle cell	3 studies	49% ± 19%	Explore
transit amplifying cell	3 studies	47% ± 36%	Explore
mural cell	3 studies	49% ± 5%	Explore
mucus secreting cell	3 studies	45% ± 14%	Explore
regulatory T cell	3 studies	32% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	19 studies	53% ± 21%	Explore
lung	9 studies	30% ± 14%	Explore
eye	7 studies	47% ± 22%	Explore
heart	5 studies	43% ± 16%	Explore
liver	4 studies	40% ± 23%	Explore
peripheral blood	3 studies	20% ± 4%	Explore
intestine	3 studies	21% ± 4%	Explore
adipose	3 studies	55% ± 22%	Explore
kidney	3 studies	43% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5869.64	1445 / 1445	100%	48.37	183 / 183
intestine	100%	6434.11	966 / 966	100%	31.18	525 / 527
ovary	100%	6374.41	180 / 180	100%	30.60	428 / 430
lung	100%	6228.40	578 / 578	99%	32.43	1149 / 1155
breast	100%	6835.31	459 / 459	99%	44.86	1110 / 1118
brain	100%	5557.88	2637 / 2642	99%	33.82	701 / 705
stomach	100%	4841.99	359 / 359	99%	33.13	283 / 286
skin	100%	8238.26	1809 / 1809	99%	36.44	466 / 472
thymus	100%	6771.46	653 / 653	99%	26.19	597 / 605
prostate	100%	6472.10	245 / 245	99%	34.69	495 / 502
bladder	100%	6149.90	21 / 21	98%	25.51	496 / 504
pancreas	100%	4555.77	328 / 328	98%	24.39	175 / 178
uterus	100%	6081.31	170 / 170	98%	24.86	449 / 459
kidney	100%	4803.17	89 / 89	97%	25.57	872 / 901
adrenal gland	100%	6150.18	258 / 258	96%	20.97	220 / 230
liver	100%	3456.63	226 / 226	83%	13.40	336 / 406
adipose	100%	6795.95	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5962.69	1335 / 1335	0%	0	0 / 0
muscle	100%	6176.62	803 / 803	0%	0	0 / 0
spleen	100%	5275.25	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	6.37	1 / 1
heart	97%	4471.62	839 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	29.67	43 / 45
eye	0%	0	0 / 0	95%	21.46	76 / 80
peripheral blood	78%	3579.89	720 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	66%	16.53	19 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0001955	Biological process	blood vessel maturation
GO_0045087	Biological process	innate immune response
GO_0051151	Biological process	negative regulation of smooth muscle cell differentiation
GO_1900087	Biological process	positive regulation of G1/S transition of mitotic cell cycle
GO_1900246	Biological process	positive regulation of RIG-I signaling pathway
GO_0043123	Biological process	positive regulation of canonical NF-kappaB signal transduction
GO_1900245	Biological process	positive regulation of MDA-5 signaling pathway
GO_0042742	Biological process	defense response to bacterium
GO_0006275	Biological process	regulation of DNA replication
GO_0045787	Biological process	positive regulation of cell cycle
GO_0016020	Cellular component	membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0001673	Cellular component	male germ cell nucleus
GO_0000785	Cellular component	chromatin
GO_0031965	Cellular component	nuclear membrane
GO_0005634	Cellular component	nucleus
GO_0003682	Molecular function	chromatin binding
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	ANKRD17
Protein name	Ankyrin repeat domain 17 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16)
Synonyms	KIAA0697 GTAR
Description	FUNCTION: Could play pivotal roles in cell cycle and DNA regulation . Involved in innate immune defense against viruse by positively regulating the viral dsRNA receptors DDX58 and IFIH1 signaling pathways . Involves in NOD2- and NOD1-mediated responses to bacteria suggesting a role in innate antibacterial immune pathways too . Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease) . Could play a central role for the formation and/or maintenance of the blood vessels of the circulation system (By similarity). .
Accessions	ENST00000358602.9 [O75179-1] ENST00000558247.5 H0YM23 ENST00000561029.1 H0YLQ3 O75179 ENST00000330838.10 [O75179-6] ENST00000509867.6 [O75179-7]

ANKRD17 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review