I. Related cell sub types
ID | Name | Number of studies  | |
|---|---|---|---|
| CL_0000938 | CD16-negative, CD56-bright natural killer cell, human | 25 | |
| CL_0000824 | mature natural killer cell | 0 |
ID | Name | Number of studies | |
|---|---|---|---|
| CL_0000938 | CD16-negative, CD56-bright natural killer cell, human | 25 | |
| CL_0000824 | mature natural killer cell | 0 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) | |
|---|---|---|---|---|---|
| KLRD1 | 18 | 79% ± 14% | 0 | 15 | |
| KLRF1 | 17 | 56% ± 21% | 0 | 5 | |
| KLRC1 | 17 | 56% ± 18% | 0 | 8 | |
| SH2D1B | 15 | 33% ± 14% | 0 | 4 | |
| XCL1 | 15 | 60% ± 18% | 0 | 9 | |
| PRF1 | 16 | 70% ± 14% | 0 | 21 | |
| PTGDR | 15 | 33% ± 12% | 0 | 11 | |
| XCL2 | 15 | 65% ± 16% | 0 | 11 | |
| ZAP70 | 16 | 41% ± 16% | 0 | 27 | |
| GZMK | 15 | 56% ± 21% | 0 | 17 | |
| IL18RAP | 13 | 23% ± 7% | 0 | 3 | |
| GZMM | 15 | 52% ± 20% | 0 | 27 | |
| SH2D1A | 14 | 29% ± 15% | 0 | 22 | |
| GZMH | 13 | 30% ± 12% | 0 | 13 | |
| NCR1 | 12 | 29% ± 8% | 0 | 3 | |
| GZMA | 18 | 69% ± 19% | 1 | 26 | |
| KLRB1 | 18 | 63% ± 23% | 1 | 26 | |
| IL2RB | 17 | 63% ± 22% | 1 | 22 | |
| GNLY | 16 | 78% ± 24% | 1 | 20 | |
| GZMB | 15 | 55% ± 18% | 1 | 17 | |
| SAMD3 | 15 | 43% ± 15% | 1 | 22 | |
| CD96 | 16 | 42% ± 16% | 2 | 33 | |
| LCK | 16 | 40% ± 18% | 2 | 34 | |
| CD247 | 16 | 65% ± 17% | 2 | 34 | |
| CD2 | 16 | 44% ± 20% | 2 | 35 | |
| CD7 | 17 | 83% ± 15% | 3 | 37 | |
| APOBEC3G | 16 | 36% ± 16% | 3 | 28 | |
| TXK | 15 | 48% ± 14% | 3 | 19 | |
| CTSW | 17 | 85% ± 17% | 4 | 31 | |
| FCER1G | 17 | 70% ± 20% | 4 | 32 |
| GO_0071636 | Biological process | positive regulation of transforming growth factor beta production |
| GO_0140507 | Biological process | granzyme-mediated programmed cell death signaling pathway |
| GO_0002726 | Biological process | positive regulation of T cell cytokine production |
| GO_0017038 | Biological process | protein import |
| GO_0043371 | Biological process | negative regulation of CD4-positive, alpha-beta T cell differentiation |
| GO_2000114 | Biological process | regulation of establishment of cell polarity |
| GO_0002725 | Biological process | negative regulation of T cell cytokine production |
| GO_0002418 | Biological process | immune response to tumor cell |
| GO_0060744 | Biological process | mammary gland branching involved in thelarche |
| GO_0031929 | Biological process | TOR signaling |
| GO_0002769 | Biological process | natural killer cell inhibitory signaling pathway |
| GO_0001915 | Biological process | negative regulation of T cell mediated cytotoxicity |
| GO_0071559 | Biological process | response to transforming growth factor beta |
| GO_0002729 | Biological process | positive regulation of natural killer cell cytokine production |
| GO_0042269 | Biological process | regulation of natural killer cell mediated cytotoxicity |
| GO_2000553 | Biological process | positive regulation of T-helper 2 cell cytokine production |
| GO_0033600 | Biological process | negative regulation of mammary gland epithelial cell proliferation |
| GO_0002520 | Biological process | immune system development |
| GO_0045953 | Biological process | negative regulation of natural killer cell mediated cytotoxicity |
| GO_0043378 | Biological process | positive regulation of CD8-positive, alpha-beta T cell differentiation |
| GO_0048646 | Biological process | anatomical structure formation involved in morphogenesis |
| GO_0002305 | Biological process | CD8-positive, gamma-delta intraepithelial T cell differentiation |
| GO_2000503 | Biological process | positive regulation of natural killer cell chemotaxis |
| GO_2000566 | Biological process | positive regulation of CD8-positive, alpha-beta T cell proliferation |
| GO_0032516 | Biological process | positive regulation of phosphoprotein phosphatase activity |
| GO_0033625 | Biological process | positive regulation of integrin activation |
| GO_2000146 | Biological process | negative regulation of cell motility |
| GO_0030856 | Biological process | regulation of epithelial cell differentiation |
| GO_0002690 | Biological process | positive regulation of leukocyte chemotaxis |
| GO_2000562 | Biological process | negative regulation of CD4-positive, alpha-beta T cell proliferation |
| Cell type name | CD16-negative, CD56-bright natural killer cell, human |
| Synonyms | CD16-CD56bright NK cell CD16-negative CD56-bright NK cell CD56-bright cytokine secreting NK cell CD56-bright cytokine secreting natural killer cell |
| Description | NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic. |
| Parent | CL_0000824 |
