GNLY report

II. Expression across tissues

III. Associated gene sets

GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0031640Biological processkilling of cells of another organism
GO_0050832Biological processdefense response to fungus
GO_0006968Biological processcellular defense response
GO_0042742Biological processdefense response to bacterium
GO_0005615Cellular componentextracellular space
GO_0097013Cellular componentphagocytic vesicle lumen
GO_0044194Cellular componentcytolytic granule
GO_0005576Cellular componentextracellular region
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGNLY
Protein nameGranulysin (Lymphokine LAG-2) (Protein NKG5) (T-cell activation protein 519)
Granulysin
Granulysin, isoform CRA_d (cDNA FLJ50974, moderately similar to Granulysin)
SynonymsNKG5
TLA519
hCG_32948
LAG2
DescriptionFUNCTION: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.

AccessionsH0YDW8
ENST00000526018.1
ENST00000263863.9 [P22749-1]
B4DJJ4
ENST00000409696.7 [P22749-2]
ENST00000524600.5
P22749
B4E3H9