GZMM report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	42 studies	58% ± 21%	Explore
CD8-positive, alpha-beta T cell	34 studies	48% ± 18%	Explore
CD4-positive, alpha-beta T cell	27 studies	31% ± 13%	Explore
T cell	23 studies	33% ± 11%	Explore
mature NK T cell	21 studies	57% ± 18%	Explore
gamma-delta T cell	17 studies	47% ± 20%	Explore
mucosal invariant T cell	16 studies	45% ± 17%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	52% ± 20%	Explore
regulatory T cell	15 studies	24% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	26% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	70% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	48% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	48% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	54% ± 21%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	31% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	50% ± 16%	Explore
T follicular helper cell	7 studies	26% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	29% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	59% ± 9%	Explore
exhausted T cell	5 studies	44% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	35% ± 8%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	37% ± 10%	Explore
CD4-positive helper T cell	4 studies	23% ± 7%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	43% ± 8%	Explore
intraepithelial lymphocyte	3 studies	24% ± 6%	Explore
innate lymphoid cell	3 studies	52% ± 21%	Explore
T-helper 17 cell	3 studies	25% ± 4%	Explore
T-helper 1 cell	3 studies	30% ± 8%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	28% ± 6%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	99%	201.63	575 / 578	81%	8.60	938 / 1155
prostate	86%	55.27	211 / 245	70%	3.85	351 / 502
uterus	82%	40.49	139 / 170	72%	7.42	330 / 459
thymus	88%	66.98	574 / 653	63%	10.03	383 / 605
liver	92%	64.64	207 / 226	60%	4.46	242 / 406
breast	79%	44.64	362 / 459	64%	6.18	719 / 1118
kidney	63%	37.03	56 / 89	77%	6.00	693 / 901
skin	56%	23.08	1014 / 1809	83%	15.44	392 / 472
stomach	82%	47.52	294 / 359	57%	3.56	163 / 286
bladder	71%	58.29	15 / 21	56%	4.48	280 / 504
intestine	72%	82.64	700 / 966	54%	3.09	282 / 527
brain	72%	51.68	1911 / 2642	45%	1.73	318 / 705
ovary	67%	27.66	120 / 180	37%	1.51	161 / 430
lymph node	0%	0	0 / 0	100%	66.02	29 / 29
spleen	100%	864.77	241 / 241	0%	0	0 / 0
adipose	87%	67.44	1048 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	87%	15.16	39 / 45
peripheral blood	84%	2057.86	780 / 929	0%	0	0 / 0
pancreas	13%	3.90	41 / 328	68%	5.96	121 / 178
adrenal gland	34%	11.01	89 / 258	37%	1.89	85 / 230
esophagus	47%	18.30	683 / 1445	19%	0.82	35 / 183
blood vessel	47%	27.05	623 / 1335	0%	0	0 / 0
heart	40%	14.80	348 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	34%	1.90	27 / 80
muscle	7%	1.94	57 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1