I. Related cell sub types
ID | Name | Number of studies  | |
|---|---|---|---|
| CL_0002038 | T follicular helper cell | 11 | |
| CL_0000492 | CD4-positive helper T cell | 7 |
ID | Name | Number of studies | |
|---|---|---|---|
| CL_0002038 | T follicular helper cell | 11 | |
| CL_0000492 | CD4-positive helper T cell | 7 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) | |
|---|---|---|---|---|---|
| CD40LG | 7 | 30% ± 7% | 0 | 10 | |
| ICOS | 7 | 39% ± 15% | 0 | 10 | |
| TIGIT | 7 | 41% ± 18% | 0 | 13 | |
| SIRPG | 7 | 24% ± 9% | 0 | 15 | |
| TRAT1 | 7 | 31% ± 10% | 0 | 20 | |
| ITK | 7 | 35% ± 10% | 0 | 22 | |
| TNFSF8 | 5 | 23% ± 4% | 0 | 4 | |
| PDCD1 | 5 | 45% ± 14% | 0 | 4 | |
| CD6 | 7 | 39% ± 5% | 0 | 24 | |
| ZAP70 | 7 | 33% ± 13% | 0 | 27 | |
| GZMM | 7 | 26% ± 7% | 0 | 27 | |
| PYHIN1 | 6 | 19% ± 2% | 0 | 19 | |
| CD5 | 6 | 29% ± 5% | 0 | 20 | |
| SH2D1A | 6 | 33% ± 12% | 0 | 22 | |
| CTLA4 | 4 | 34% ± 11% | 0 | 3 | |
| CD3G | 10 | 52% ± 15% | 1 | 29 | |
| CD27 | 9 | 44% ± 15% | 1 | 30 | |
| KLRB1 | 8 | 47% ± 15% | 1 | 26 | |
| TCF7 | 8 | 52% ± 15% | 1 | 27 | |
| CD28 | 6 | 27% ± 6% | 1 | 12 | |
| TRAF1 | 5 | 17% ± 2% | 1 | 6 | |
| LCK | 10 | 57% ± 15% | 2 | 34 | |
| CD3D | 10 | 84% ± 10% | 2 | 34 | |
| CD2 | 10 | 69% ± 15% | 2 | 35 | |
| PASK | 7 | 36% ± 15% | 2 | 9 | |
| DENND2D | 8 | 34% ± 10% | 2 | 23 | |
| SIT1 | 7 | 21% ± 4% | 2 | 24 | |
| CD3E | 10 | 81% ± 15% | 3 | 37 | |
| CD7 | 10 | 59% ± 17% | 3 | 37 | |
| LAT | 8 | 57% ± 14% | 3 | 29 |
| GO_0070092 | Biological process | regulation of glucagon secretion |
| GO_0002903 | Biological process | negative regulation of B cell apoptotic process |
| GO_0045190 | Biological process | isotype switching |
| GO_0045719 | Biological process | negative regulation of glycogen biosynthetic process |
| GO_0002841 | Biological process | negative regulation of T cell mediated immune response to tumor cell |
| GO_0043576 | Biological process | regulation of respiratory gaseous exchange |
| GO_0070234 | Biological process | positive regulation of T cell apoptotic process |
| GO_0042532 | Biological process | negative regulation of tyrosine phosphorylation of STAT protein |
| Cell type name | T follicular helper cell |
| Synonyms | T(FH) Tfh |
| Description | A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. |
| Parent | CL_0000492 |
