Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| regulatory T cell | 17 studies | 34% ± 13% | |
| CD8-positive, alpha-beta T cell | 10 studies | 33% ± 12% | |
| CD4-positive, alpha-beta T cell | 9 studies | 27% ± 10% | |
| T cell | 8 studies | 22% ± 6% | |
| naive thymus-derived CD8-positive, alpha-beta T cell | 7 studies | 20% ± 4% | |
| T follicular helper cell | 7 studies | 24% ± 9% | |
| mucosal invariant T cell | 6 studies | 19% ± 3% | |
| CD4-positive, alpha-beta memory T cell | 5 studies | 22% ± 8% | |
| CD8-positive, alpha-beta memory T cell | 5 studies | 23% ± 8% | |
| gamma-delta T cell | 5 studies | 29% ± 6% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 5 studies | 19% ± 4% | |
| exhausted T cell | 4 studies | 41% ± 14% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 23% ± 5% | |
| intraepithelial lymphocyte | 3 studies | 25% ± 6% | |
| effector CD4-positive, alpha-beta T cell | 3 studies | 28% ± 3% | |
| effector CD8-positive, alpha-beta T cell | 3 studies | 19% ± 4% |
Insufficient scRNA-seq data for expression of SIRPG at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 93% | 64.86 | 538 / 578 | 74% | 5.12 | 854 / 1155 |
| stomach | 70% | 35.81 | 253 / 359 | 61% | 4.35 | 175 / 286 |
| intestine | 60% | 156.61 | 579 / 966 | 56% | 3.29 | 293 / 527 |
| prostate | 78% | 47.08 | 192 / 245 | 29% | 1.29 | 147 / 502 |
| bladder | 57% | 44.43 | 12 / 21 | 50% | 3.23 | 252 / 504 |
| thymus | 64% | 69.16 | 416 / 653 | 43% | 6.14 | 258 / 605 |
| kidney | 48% | 30.98 | 43 / 89 | 53% | 4.42 | 475 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 44.05 | 29 / 29 |
| spleen | 100% | 682.44 | 241 / 241 | 0% | 0 | 0 / 0 |
| uterus | 41% | 11.89 | 69 / 170 | 57% | 4.51 | 261 / 459 |
| esophagus | 35% | 18.07 | 501 / 1445 | 55% | 3.28 | 100 / 183 |
| breast | 38% | 14.24 | 176 / 459 | 51% | 3.75 | 569 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 12.74 | 40 / 45 |
| liver | 62% | 19.91 | 141 / 226 | 25% | 1.93 | 100 / 406 |
| peripheral blood | 86% | 349.19 | 797 / 929 | 0% | 0 | 0 / 0 |
| skin | 20% | 5.28 | 353 / 1809 | 62% | 9.43 | 291 / 472 |
| pancreas | 9% | 2.46 | 30 / 328 | 54% | 3.48 | 96 / 178 |
| adipose | 55% | 21.49 | 666 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 11% | 3.60 | 19 / 180 | 33% | 1.43 | 140 / 430 |
| adrenal gland | 35% | 10.68 | 91 / 258 | 3% | 0.16 | 8 / 230 |
| blood vessel | 27% | 12.87 | 356 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 18% | 1.68 | 14 / 80 |
| brain | 9% | 1.99 | 250 / 2642 | 2% | 0.13 | 17 / 705 |
| heart | 10% | 2.95 | 84 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.30 | 7 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0022409 | Biological process | positive regulation of cell-cell adhesion |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0050870 | Biological process | positive regulation of T cell activation |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0050766 | Biological process | positive regulation of phagocytosis |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SIRPG |
| Protein name | Signal-regulatory protein gamma (SIRP-gamma) (CD172 antigen-like family member B) (Signal-regulatory protein beta-2) (SIRP-b2) (SIRP-beta-2) (CD antigen CD172g) |
| Synonyms | SIRPB2 |
| Description | FUNCTION: Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. . |
| Accessions | ENST00000381580.5 [Q9P1W8-2] Q9P1W8 ENST00000303415.7 [Q9P1W8-1] ENST00000381583.6 [Q9P1W8-4] ENST00000216927.4 [Q9P1W8-4] ENST00000344103.8 [Q9P1W8-3] |