Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 983.65 | 651 / 653 | 94% | 57.77 | 570 / 605 |
| stomach | 94% | 504.38 | 337 / 359 | 99% | 17.20 | 282 / 286 |
| intestine | 93% | 1054.21 | 894 / 966 | 98% | 18.06 | 519 / 527 |
| pancreas | 99% | 722.35 | 326 / 328 | 92% | 7.32 | 163 / 178 |
| lung | 99% | 707.88 | 575 / 578 | 86% | 5.89 | 991 / 1155 |
| breast | 97% | 604.86 | 443 / 459 | 85% | 6.73 | 946 / 1118 |
| ovary | 85% | 230.16 | 153 / 180 | 92% | 8.21 | 396 / 430 |
| skin | 90% | 468.13 | 1622 / 1809 | 86% | 9.79 | 408 / 472 |
| prostate | 98% | 653.11 | 241 / 245 | 76% | 3.70 | 382 / 502 |
| esophagus | 78% | 256.70 | 1126 / 1445 | 93% | 9.20 | 171 / 183 |
| liver | 97% | 374.56 | 219 / 226 | 68% | 5.62 | 275 / 406 |
| adrenal gland | 100% | 649.12 | 257 / 258 | 59% | 4.22 | 136 / 230 |
| bladder | 76% | 363.43 | 16 / 21 | 81% | 7.66 | 407 / 504 |
| uterus | 64% | 250.21 | 109 / 170 | 89% | 7.82 | 410 / 459 |
| kidney | 92% | 464.29 | 82 / 89 | 57% | 2.66 | 512 / 901 |
| brain | 58% | 155.77 | 1539 / 2642 | 44% | 2.04 | 313 / 705 |
| spleen | 100% | 2748.47 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 4082.13 | 920 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 8.30 | 44 / 45 |
| eye | 0% | 0 | 0 / 0 | 96% | 6.05 | 77 / 80 |
| adipose | 96% | 351.27 | 1156 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 20.77 | 26 / 29 |
| heart | 63% | 154.31 | 546 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 27% | 87.33 | 362 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 2% | 4.02 | 17 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0045586 | Biological process | regulation of gamma-delta T cell differentiation |
| GO_0071353 | Biological process | cellular response to interleukin-4 |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_0006955 | Biological process | immune response |
| GO_0042492 | Biological process | gamma-delta T cell differentiation |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016604 | Cellular component | nuclear body |
| GO_1990907 | Cellular component | beta-catenin-TCF complex |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0008013 | Molecular function | beta-catenin binding |
| GO_0001217 | Molecular function | DNA-binding transcription repressor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TCF7 |
| Protein name | Transcription factor 7 Transcription factor 7 (TCF-7) (T-cell-specific transcription factor 1) (T-cell factor 1) (TCF-1) |
| Synonyms | hCG_16589 TCF1 |
| Description | FUNCTION: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages (By similarity). Required for the development of natural killer receptor-positive lymphoid tissue inducer T-cells (By similarity). TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. . |
| Accessions | ENST00000520958.5 [P36402-6] ENST00000395023.5 [P36402-6] H0YBM1 ENST00000395029.5 H0YBP2 ENST00000522375.6 ENST00000517741.5 ENST00000517851.5 ENST00000521639.5 E5RHL1 ENST00000518915.5 [P36402-2] E5RG34 ENST00000342854.10 [P36402-5] ENST00000517855.5 E5RGQ1 ENST00000520699.1 E5RGJ5 ENST00000517799.5 ENST00000518887.5 ENST00000378560.8 [P36402-8] H0YAR8 P36402 ENST00000519447.5 H0YBC8 B7WNT5 ENST00000520652.5 E5RG75 E5RJ51 ENST00000519037.5 |
