GO_0045892 | OmnibusX

negative regulation of DNA-templated transcription

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	TNFSF4-TNFRSF4	TNFL4_HUMAN - TNR4_HUMAN	Ligand-Receptor	Signaling by Tumor necrosis factor
2	WNT11-FZD1+LRP5	WNT11_HUMAN -	Ligand-Receptor	Signaling by WNT
3	WNT11-FZD1+LRP6	WNT11_HUMAN -	Ligand-Receptor	Signaling by WNT
4	WNT11-SFRP1	WNT11_HUMAN - SFRP1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
5	WNT11-SFRP2	WNT11_HUMAN - SFRP2_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
6	WNT4-FZD1+LRP5	WNT4_HUMAN -	Ligand-Receptor	Signaling by WNT
7	WNT4-FZD1+LRP6	WNT4_HUMAN -	Ligand-Receptor	Signaling by WNT
8	WNT4-SFRP1	WNT4_HUMAN - SFRP1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
9	WNT4-SFRP2	WNT4_HUMAN - SFRP2_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
10	WNT5A-SFRP1	WNT5A_HUMAN - SFRP1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
11	WNT5A-SFRP2	WNT5A_HUMAN - SFRP2_HUMAN	Ligand-Ligand	Signaling by WNT inhibition

II. Literature review

Name	negative regulation of DNA-templated transcription
ID	GO_0045892
collection_id	Biological process
Alternative ID	GO:0016481, GO:0032582, GO:0061021
Exact synonym	down regulation of transcription, DNA-dependent, down-regulation of transcription, DNA-dependent, downregulation of transcription, DNA-dependent, negative regulation of cellular transcription, DNA-dependent, negative regulation of transcription, DNA-dependent, negative regulation of transcription, DNA-templated
Description	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
Related synonym	down regulation of gene-specific transcription, down-regulation of gene-specific transcription, downregulation of gene-specific transcription, inhibition of gene-specific transcription, negative regulation of gene-specific transcription, transcription repressor activity
External URL
Genes	PER2 THRA TBR1 EID1 YAF2 prc1_human-71 ZC3H6 PRAME CIPC DAXX TBX3 PSPC1 HNRNPL TRIM6 RCOR1 ZMYND11 CITED1 prc1_human-14 LHX1 C1D DMAP1 NR1I2 prc1_human-68 CTCF RIPPLY1 ZNF318 HMGA1 SOX18 PRAMEF13 RUNX2 prc1_human-12 VGLL4 PASD1 CALCA ZNF219 SUV39H2 KDM1A IFNL1 CALR prc1_human-60 MAEL PRAMEF10 IFNA2 ELF3 RASD1 prc1_human-62 GATAD2A TWIST2 BCL3 ID4 NONO PRAMEF25 NR0B1 GREM1 SMURF2 ZNF568 SRSF2 ZNF639 WNT11 prc1_human-39 CREG1 ZNF174 BTAF1 COMMD7 PSMC5 SPEN BRCA1 LHX9 YWHAQ PATZ1 CDKN1C ARID5B CDYL prc1_human-19 KAT8 CBX1 SCX prc1_human-32 ZHX2 GLIS2 PRAMEF17 CIART TBX22 TLE1 SMYD1 BASP1 GLI3 TMPRSS6 prc1_human-42 FOXP3 CD38 CDKN2A prc1_human-8 RBBP4 ZBTB16 TLE5 HNF4A PRAMEF6 BRD7 TCF7 ARID4A prc1_human-15 prc1_human-65 XCL1 PRAMEF19 SIX3 MBD3 ZNF282 SMARCE1 KHDRBS1 prc1_human-59 ZNF423 MECP2 RORB MTA2 WWP1 TBX2 RBAK ZBED6 ZMYM2 prc1_human-38 CBFA2T3 NR2F2 PRMT5 NR1D2 NR1H2 PRAMEF27 BCL6 ZNF540 prc1_human-35 TRIM11 MBTD1 prc1_human-41 ZHX3 TIMELESS RIOX2 ZNF425 HIF1AN RSF1 STRN3 prc1_human-10 prc1_human-64 ZNF777 prc1_human-69 prc1_human-93 DHRS7B NOSTRIN THAP7 SFRP1 NR1D1 CIR1 MYF6 EHMT1 ZNF253 prc1_human-44 NIBAN2 CEBPA FOXD1 PCGF6 prc1_human-72 BMP7 ID3 IKZF4 PRDM16 p53-mdm2_human PRAMEF18 HMGB2 FOXG1 ZNF217 TLE3 ILF3 ZSCAN10 FOXP1 PROX1 MDM4 PDCD4 prc1_human-23 ATF7IP BMAL1 CITED2 RUNX1T1 MSX2 SUMO1 ZKSCAN3 DDIT3 EED PRICKLE1 HEYL TAF7 TRIB3 MYB IKZF1 UBE2I LIMS1 prc1_human-11 CIC TWIST1 SUMO4 HEY2 CREB3L1 prc1_human-63 MTA3 PHB2 HSBP1L1 SALL1 ID2 PPARG SCAI kiaa0409-suv39h1_human TGFB1 GMNN SNW1 CASP8AP2 L3MBTL3 ZNF827 ZBTB33 prc1_human-28 ZNF746 SMAD2 MBD2 prc1_human-95 ZNF541 POU3F3 prc1_human-52 RLIM prc1_human-30 mbd3/nurd_human TDP2 TP53 prc1_human-73 MAP3K10 CHD3 RPS6KA5 CCAR1 HOXA7 ATP8B1 NACC2 DEDD2 SCML1 TBX20 RBFOX2 PHF12 HEXIM2 BCL7A KAT6A ZNF488 EPC1 DKK3 SAMD11 prc1_human-66 LEF1 ATOH8 ALX1 NOTCH1 HDAC5 NPAT prc1_human-43 ZIC2 ZNF12 BAHD1 KDM5B SIX5 TRIM33 prc1_human-21 SIN3A RB1 EREG TCF7L2 prc1_human-67 ZNF256 PRAMEF33 ZBTB21 ZBTB18 APEX1 CHD4 BHLHE40 GFI1 BCOR KMT5A L3MBTL4 TFDP2 DAP CEBPD TRIM28 SAMD7 BCLAF1 RUVBL2 EID2 REST prc1_human-24 RBM15B PRAMEF4 NCOR1 RCOR3 prc1_human-49 CDYL2 HES1 ZNF281 TNP1 NCOR2 TOB1 prc1_human-56 prc1_human-1 CBX4 GZF1 prc1_human-22 ATF5 PRAMEF20 prc1_human-50 HEY1 NRG1 PARP1 prc1_human-6 SMARCA2 ATXN1 SMARCA4 PML CCAR2 prc1_human-45 SCMH1 CBY1 ZBTB4 XRCC6 TBX21 RARA TNFRSF4 prc1_human-5 RFX3 RRP8 FOXM1 HAND1 prc1_human-48 FABP4 TSHZ3 prc1_human-55 TNFSF4 KCTD1 SIRT1 prc1_human-17 SFMBT2 SFRP2 RIOX1 SCML2 PRMT6 CRY2 PRDM5 TLE7 prc1_human-70 PRAMEF22 prc1_human-47 TOB2 SCML4 HIRA SIAH2 SETDB2 dream_human PRAMEF12 PPARD XRCC5 ING4 BMP2 DAB2IP MESP1 CDK5 PEX14 prc1_human-7 prc1_human-33 CRYAB SF1 PFDN5 ZNF24 PRAMEF26 ZHX1 AHR PRAMEF15 prc1_human-13 MLX CSF2 MLXIPL prc1_human-58 SPI1 PRAMEF2 TFAP2A UIMC1 ZNF224 SIX4 TCEAL7 CNOT7 ZEB1 HSPA8 WNT4 ZC3H8 BHLHE41 CDK5R1 prc1_human-3 CENPF NKAP PARP14 L3MBTL2 HDAC2 IL4 DMBX1 TP63 PTPRK PRAMEF7 PLCB1 prc1_human-53 BMP4 ZNF148 CBFA2T2 HDAC3 PRAMEF9 NFIL3 FZD1 JUN TSC22D4 p53-mdm2_human-1 PHF24 SFPQ L3MBTL1 SP3 CBX5 VDR CDKN1B PHB1 FOXK1 CTBP1 PPM1F KLF10 TNF prc1_human-18 CDY2A EID2B CLOCK KLF4 SHC1 SAP18 TRIM22 prc1_human-51 prc1_human-20 HHEX ZNF503 SET PARP10 HINFP ESX1 NDUFA13 PHC2 FOXF2 PRMT2 BIRC5 prc1_human-36 SNX6 PA2G4 POU2F1 ID1 ZBTB38 INPP5K NACC1 MDM2 HDAC6 CCDC85B PRDM8 NKX2-1 SMAD4 prc1_human-16 SIRT2 DDX54 MDFIC GAS6 BAP1 PBXIP1 TRIM24 prc1_human-94 WT1 TLE2 DNAJB6 FERD3L LOXL2 SOX7 SUV39H1 PRAMEF5 ARK2N prc1_human-4 ZBTB7A HDAC1 IFNG ZBTB14 TFAP4 PITX1 ACTRT1 TFAP2B GATA3 FOXN3 BEND6 ZNF418 PAX9 prc1_human-37 EZH2 TBL1Y IFI16 PDGFB prc1_human-40 HNRNPK LIMD1 dream_human-1 NR0B2 CRY1 MECOM PPHLN1 cry2-per2_human HDAC10 BEND5 HIC2 ZP3 NAB1 KDM5C BTRC FOXS1 CREBZF RING1 prc1_human-9 LDB1 RELA CBX3 prc1_human-92 p53-mdmx_human MTERF3 TRAF6 PRAMEF14 WWP2 DEAF1 SOX6 KAT6B HMGA2 CDY1 KDM4A ZNF350 PHC3 SUDS3 ZFTA PRDM11 RBBP7 BRMS1 MYBBP1A NKX6-2 TRERF1 CIITA MIDEAS prc1_human-25 MBD1 ENO1 HDAC9 FOXP2 FOXL2 LANCL2 prc1_human-54 LOXL3 DEPDC1 SMTNL1 PRAMEF1 l3mbtl-cbx3_human RBBP8 LBH prc1_human-31 ZMYND15 MAGEL2 ZNF658 SMARCC2 PPARGC1B FBXW11 SOX9 prc1_human-34 NMNAT1 IRF1 WNT5A RERE GATA6 FOXK2 SFMBT1 prc1_human-61 NKX2-5 RCOR2 prc1_human-26 CAPN3 PHC1 ZNF703 RELB ZFPM2 KAT5 MEN1 prc1_human-29 SBNO2 PIAS4 SPINDOC ASCL1 RBM15 HMBOX1 SOX13 WTIP ADIPOQ PER1 PRAMEF8 DACH1 GCLC ANKRD1 KDM8 GATAD2B FOXO1 ERN2 E2F1 MTA1 NKRF PAX2 PRAMEF11 SOX8 prc1_human-46 CHD8 ZNF706 prc1_human-57 CTNNB1 SOX14 ARID5A NPAS1 NKX3-1 HMX1 QARS1 RBPJ USP47 CTBP2 DNMT3A ZGPAT NR3C1 prc1_human-2