BCLAF1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	41 studies	32% ± 11%	Explore
B cell	38 studies	35% ± 12%	Explore
fibroblast	38 studies	29% ± 11%	Explore
natural killer cell	36 studies	35% ± 11%	Explore
CD8-positive, alpha-beta T cell	32 studies	32% ± 12%	Explore
T cell	31 studies	29% ± 12%	Explore
pericyte	31 studies	27% ± 10%	Explore
CD4-positive, alpha-beta T cell	31 studies	33% ± 12%	Explore
macrophage	27 studies	27% ± 8%	Explore
smooth muscle cell	25 studies	28% ± 9%	Explore
conventional dendritic cell	25 studies	35% ± 18%	Explore
regulatory T cell	24 studies	33% ± 12%	Explore
classical monocyte	24 studies	34% ± 15%	Explore
mast cell	21 studies	28% ± 10%	Explore
non-classical monocyte	21 studies	33% ± 16%	Explore
memory B cell	20 studies	42% ± 12%	Explore
naive B cell	19 studies	38% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	33% ± 13%	Explore
plasmacytoid dendritic cell	18 studies	41% ± 16%	Explore
ciliated cell	18 studies	41% ± 14%	Explore
mature NK T cell	18 studies	33% ± 8%	Explore
monocyte	17 studies	27% ± 8%	Explore
endothelial cell of lymphatic vessel	17 studies	29% ± 9%	Explore
epithelial cell	17 studies	35% ± 21%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	39% ± 15%	Explore
gamma-delta T cell	16 studies	41% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	39% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	36% ± 13%	Explore
basal cell	14 studies	34% ± 12%	Explore
dendritic cell	13 studies	43% ± 22%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	37% ± 14%	Explore
plasma cell	13 studies	27% ± 12%	Explore
connective tissue cell	13 studies	32% ± 10%	Explore
capillary endothelial cell	13 studies	24% ± 7%	Explore
myofibroblast cell	13 studies	34% ± 13%	Explore
vein endothelial cell	13 studies	27% ± 9%	Explore
mucosal invariant T cell	13 studies	37% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	37% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	42% ± 15%	Explore
oligodendrocyte precursor cell	12 studies	28% ± 12%	Explore
astrocyte	12 studies	33% ± 13%	Explore
endothelial cell of artery	11 studies	23% ± 5%	Explore
microglial cell	11 studies	27% ± 9%	Explore
endothelial cell of vascular tree	11 studies	28% ± 8%	Explore
myeloid cell	11 studies	31% ± 17%	Explore
oligodendrocyte	11 studies	30% ± 11%	Explore
type II pneumocyte	10 studies	27% ± 10%	Explore
club cell	10 studies	28% ± 12%	Explore
glutamatergic neuron	10 studies	39% ± 24%	Explore
type I pneumocyte	9 studies	30% ± 11%	Explore
plasmablast	9 studies	48% ± 20%	Explore
secretory cell	9 studies	28% ± 9%	Explore
mesothelial cell	9 studies	31% ± 13%	Explore
abnormal cell	8 studies	35% ± 11%	Explore
neuron	8 studies	34% ± 16%	Explore
retinal rod cell	8 studies	22% ± 5%	Explore
respiratory goblet cell	7 studies	26% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	30% ± 8%	Explore
leukocyte	7 studies	33% ± 10%	Explore
GABAergic neuron	7 studies	43% ± 19%	Explore
progenitor cell	7 studies	36% ± 12%	Explore
goblet cell	7 studies	34% ± 21%	Explore
interneuron	7 studies	39% ± 24%	Explore
hematopoietic stem cell	7 studies	48% ± 13%	Explore
precursor B cell	7 studies	48% ± 18%	Explore
T follicular helper cell	7 studies	36% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	27% ± 7%	Explore
amacrine cell	6 studies	32% ± 6%	Explore
lymphocyte	6 studies	38% ± 11%	Explore
adipocyte	6 studies	28% ± 4%	Explore
innate lymphoid cell	6 studies	35% ± 9%	Explore
alveolar macrophage	5 studies	27% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	37% ± 14%	Explore
hematopoietic precursor cell	5 studies	54% ± 17%	Explore
mononuclear phagocyte	5 studies	31% ± 12%	Explore
pro-B cell	5 studies	49% ± 17%	Explore
immature B cell	5 studies	46% ± 11%	Explore
retinal cone cell	5 studies	33% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	42% ± 13%	Explore
CD4-positive helper T cell	4 studies	36% ± 17%	Explore
deuterosomal cell	4 studies	32% ± 4%	Explore
ionocyte	4 studies	30% ± 12%	Explore
precursor cell	4 studies	39% ± 20%	Explore
pancreatic A cell	4 studies	51% ± 18%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	36% ± 14%	Explore
exhausted T cell	4 studies	33% ± 12%	Explore
retinal bipolar neuron	4 studies	29% ± 7%	Explore
glial cell	4 studies	29% ± 13%	Explore
granule cell	4 studies	19% ± 3%	Explore
retinal ganglion cell	4 studies	34% ± 13%	Explore
brush cell	4 studies	35% ± 18%	Explore
retina horizontal cell	4 studies	35% ± 9%	Explore
Mueller cell	4 studies	27% ± 5%	Explore
intermediate monocyte	4 studies	43% ± 24%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	24% ± 5%	Explore
hepatocyte	4 studies	41% ± 21%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	51% ± 29%	Explore
erythrocyte	4 studies	42% ± 12%	Explore
T-helper 17 cell	4 studies	30% ± 10%	Explore
double negative thymocyte	4 studies	49% ± 15%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	20% ± 6%	Explore
pancreatic D cell	3 studies	44% ± 25%	Explore
type B pancreatic cell	3 studies	55% ± 19%	Explore
glomerular endothelial cell	3 studies	27% ± 5%	Explore
podocyte	3 studies	34% ± 13%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	32% ± 8%	Explore
neural crest cell	3 studies	39% ± 4%	Explore
GABAergic interneuron	3 studies	26% ± 1%	Explore
kidney loop of Henle epithelial cell	3 studies	20% ± 1%	Explore
placental villous trophoblast	3 studies	28% ± 6%	Explore
erythroblast	3 studies	57% ± 24%	Explore
retinal pigment epithelial cell	3 studies	35% ± 10%	Explore
tissue-resident macrophage	3 studies	32% ± 14%	Explore
OFF-bipolar cell	3 studies	29% ± 10%	Explore
ON-bipolar cell	3 studies	32% ± 9%	Explore
rod bipolar cell	3 studies	38% ± 6%	Explore
acinar cell	3 studies	38% ± 16%	Explore
germinal center B cell	3 studies	28% ± 5%	Explore
muscle cell	3 studies	43% ± 19%	Explore
pancreatic ductal cell	3 studies	52% ± 24%	Explore
neural progenitor cell	3 studies	26% ± 10%	Explore
ependymal cell	3 studies	34% ± 12%	Explore
granulocyte	3 studies	29% ± 4%	Explore
enteroendocrine cell	3 studies	33% ± 12%	Explore
adventitial cell	3 studies	26% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	51% ± 17%	Explore
transit amplifying cell	3 studies	32% ± 19%	Explore
T-helper 1 cell	3 studies	36% ± 15%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	37% ± 5%	Explore
double-positive, alpha-beta thymocyte	3 studies	56% ± 13%	Explore
myoepithelial cell	3 studies	25% ± 4%	Explore
IgA plasma cell	3 studies	22% ± 5%	Explore
IgG plasma cell	3 studies	20% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	28% ± 10%	Explore
peripheral blood	18 studies	37% ± 14%	Explore
brain	16 studies	34% ± 18%	Explore
intestine	9 studies	29% ± 10%	Explore
eye	9 studies	28% ± 8%	Explore
kidney	6 studies	26% ± 6%	Explore
lymph node	5 studies	31% ± 11%	Explore
liver	5 studies	32% ± 13%	Explore
bone marrow	4 studies	38% ± 18%	Explore
uterus	4 studies	40% ± 12%	Explore
breast	4 studies	24% ± 6%	Explore
pancreas	3 studies	54% ± 18%	Explore
placenta	3 studies	22% ± 5%	Explore
heart	3 studies	19% ± 0%	Explore
adipose	3 studies	28% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	9821.99	459 / 459	100%	59.40	1118 / 1118
esophagus	100%	7416.31	1445 / 1445	100%	55.96	183 / 183
lung	100%	8201.85	578 / 578	100%	40.70	1155 / 1155
ovary	100%	12313.12	180 / 180	100%	31.25	430 / 430
prostate	100%	9101.90	245 / 245	100%	47.96	502 / 502
uterus	100%	11186.37	170 / 170	100%	39.65	459 / 459
thymus	100%	9821.72	653 / 653	100%	48.25	603 / 605
brain	100%	6254.39	2631 / 2642	100%	47.52	705 / 705
pancreas	100%	4700.10	328 / 328	99%	32.56	177 / 178
bladder	100%	9188.29	21 / 21	99%	36.46	499 / 504
adrenal gland	100%	7318.18	258 / 258	98%	36.89	226 / 230
stomach	100%	6261.00	359 / 359	98%	44.19	281 / 286
kidney	100%	5262.70	89 / 89	98%	31.55	884 / 901
intestine	100%	8234.97	966 / 966	98%	40.13	515 / 527
skin	100%	9285.47	1809 / 1809	95%	34.72	449 / 472
liver	100%	3435.17	226 / 226	95%	16.75	384 / 406
blood vessel	100%	7963.35	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	35.92	29 / 29
muscle	100%	5626.90	803 / 803	0%	0	0 / 0
spleen	100%	8851.13	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	38.04	45 / 45
ureter	0%	0	0 / 0	100%	12.32	1 / 1
adipose	100%	9152.09	1203 / 1204	0%	0	0 / 0
heart	98%	4271.42	841 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	88%	19.57	70 / 80
peripheral blood	86%	4879.00	795 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006915	Biological process	apoptotic process
GO_0006974	Biological process	DNA damage response
GO_2001244	Biological process	positive regulation of intrinsic apoptotic signaling pathway
GO_1990830	Biological process	cellular response to leukemia inhibitory factor
GO_0043065	Biological process	positive regulation of apoptotic process
GO_2000144	Biological process	positive regulation of DNA-templated transcription initiation
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0016607	Cellular component	nuclear speck
GO_0016592	Cellular component	mediator complex
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding
GO_0003712	Molecular function	transcription coregulator activity
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	BCLAF1
Protein name	BCL2 associated transcription factor 1 BCLAF1 protein Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1)
Synonyms	BTF KIAA0164
Description	FUNCTION: Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. .
Accessions	ENST00000532384.5 ENST00000527613.5 E9PKI6 ENST00000628517.2 Q9NYF8 ENST00000527536.5 ENST00000392348.6 [Q9NYF8-3] ENST00000534269.5 ENST00000530429.5 E9PK09 E9PJA7 ENST00000640069.1 ENST00000531224.6 [Q9NYF8-1] ENST00000529826.5 A0A1W2PQ43 H0YF63 E9PK91 H0YF00 ENST00000533422.5 ENST00000353331.8 [Q9NYF8-3] E9PQN2 ENST00000534762.5 ENST00000533621.1 Q6DCA8 ENST00000527759.5 [Q9NYF8-2] H0YF14 ENST00000530767.5 [Q9NYF8-4]

BCLAF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review