I. Related cell sub types
ID | Name | Number of studies  | |
|---|---|---|---|
| CL_0002063 | type II pneumocyte | 16 | |
| CL_0000322 | pneumocyte | 2 |
ID | Name | Number of studies | |
|---|---|---|---|
| CL_0002063 | type II pneumocyte | 16 | |
| CL_0000322 | pneumocyte | 2 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) | |
|---|---|---|---|---|---|
| PGC | 11 | 54% ± 27% | 0 | 1 | |
| ALOX15B | 10 | 25% ± 8% | 0 | 0 | |
| CLDN18 | 10 | 53% ± 18% | 0 | 1 | |
| SLC22A31 | 10 | 39% ± 16% | 0 | 1 | |
| SUSD2 | 9 | 34% ± 12% | 0 | 1 | |
| LAMP3 | 12 | 66% ± 17% | 1 | 3 | |
| NKX2-1 | 12 | 50% ± 18% | 1 | 5 | |
| SLC34A2 | 12 | 83% ± 16% | 1 | 7 | |
| SFTPD | 11 | 70% ± 27% | 1 | 2 | |
| CACNA2D2 | 11 | 39% ± 12% | 1 | 3 | |
| SFTA3 | 11 | 78% ± 9% | 1 | 5 | |
| ITGB6 | 11 | 41% ± 16% | 1 | 6 | |
| TMPRSS2 | 11 | 31% ± 11% | 1 | 12 | |
| DUOXA1 | 10 | 27% ± 6% | 1 | 3 | |
| AQP4 | 10 | 35% ± 17% | 1 | 4 | |
| SDR16C5 | 10 | 45% ± 21% | 1 | 6 | |
| KCNJ15 | 12 | 36% ± 17% | 2 | 5 | |
| ALPL | 11 | 40% ± 16% | 2 | 3 | |
| C4BPA | 11 | 50% ± 20% | 2 | 3 | |
| SFTPA2 | 11 | 82% ± 20% | 2 | 4 | |
| DUOX1 | 11 | 42% ± 12% | 2 | 7 | |
| GPRC5A | 12 | 42% ± 18% | 2 | 17 | |
| RHOBTB2 | 10 | 30% ± 11% | 2 | 3 | |
| VEPH1 | 10 | 41% ± 15% | 2 | 3 | |
| C16orf89 | 10 | 58% ± 24% | 2 | 5 | |
| NAPSA | 12 | 79% ± 20% | 3 | 8 | |
| WIF1 | 12 | 52% ± 16% | 3 | 8 | |
| ADGRF5 | 12 | 54% ± 17% | 3 | 16 | |
| ABCA3 | 11 | 72% ± 13% | 3 | 10 | |
| MFSD2A | 12 | 45% ± 18% | 4 | 6 |
| GO_0015793 | Biological process | glycerol transmembrane transport |
| GO_1902236 | Biological process | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway |
| GO_0060510 | Biological process | type II pneumocyte differentiation |
| GO_0071073 | Biological process | positive regulation of phospholipid biosynthetic process |
| GO_0033619 | Biological process | membrane protein proteolysis |
| GO_0019370 | Biological process | leukotriene biosynthetic process |
| GO_0035455 | Biological process | response to interferon-alpha |
| GO_0061026 | Biological process | cardiac muscle tissue regeneration |
| GO_0046890 | Biological process | regulation of lipid biosynthetic process |
| GO_1901799 | Biological process | negative regulation of proteasomal protein catabolic process |
| GO_0006665 | Biological process | sphingolipid metabolic process |
| GO_0021759 | Biological process | globus pallidus development |
| GO_0060486 | Biological process | club cell differentiation |
| GO_0044341 | Biological process | sodium-dependent phosphate transport |
| GO_2001140 | Biological process | positive regulation of phospholipid transport |
| GO_1902995 | Biological process | positive regulation of phospholipid efflux |
| GO_0048646 | Biological process | anatomical structure formation involved in morphogenesis |
| GO_0042753 | Biological process | positive regulation of circadian rhythm |
| GO_1904936 | Biological process | interneuron migration |
| GO_1902902 | Biological process | negative regulation of autophagosome assembly |
| GO_0061520 | Biological process | Langerhans cell differentiation |
| GO_0150011 | Biological process | regulation of neuron projection arborization |
| GO_0006817 | Biological process | phosphate ion transport |
| GO_0071578 | Biological process | zinc ion import across plasma membrane |
| GO_0046618 | Biological process | xenobiotic export from cell |
| GO_0046471 | Biological process | phosphatidylglycerol metabolic process |
| GO_0009992 | Biological process | intracellular water homeostasis |
| GO_0021854 | Biological process | hypothalamus development |
| GO_0072594 | Biological process | establishment of protein localization to organelle |
| GO_0006824 | Biological process | cobalt ion transport |
| Cell type name | type II pneumocyte |
| Synonyms | AT2 ATII TII cuboidal type II cell granular pneumocyte great alveolar cell lung type 2 cell type 2 alveolar epithelial cell type 2 alveolocyte type 2 pneumocyte type II alveolar cell type II alveolar epithelial cell type II alveolocyte |
| Description | A type II pneumocyte is a pneumocyte that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants. This cell type also contributes to tissue repair and can differentiate after injury into a type I pneumocyte. Thicker than squamous alveolar cells, have a rounded apical surface that projects above the level of surrounding epithelium. The free surface is covered by short microvilli. |
| Parent | CL_0000322 |
