Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 16 studies | 44% ± 25% | |
| basal cell | 15 studies | 34% ± 12% | |
| type I pneumocyte | 12 studies | 85% ± 10% | |
| type II pneumocyte | 12 studies | 42% ± 18% | |
| fibroblast | 10 studies | 41% ± 9% | |
| club cell | 9 studies | 52% ± 19% | |
| respiratory goblet cell | 7 studies | 37% ± 15% | |
| secretory cell | 7 studies | 62% ± 15% | |
| ciliated cell | 6 studies | 34% ± 12% | |
| enterocyte | 6 studies | 21% ± 3% | |
| pericyte | 5 studies | 17% ± 1% | |
| squamous epithelial cell | 4 studies | 56% ± 19% | |
| adventitial cell | 4 studies | 20% ± 3% | |
| luminal hormone-sensing cell of mammary gland | 4 studies | 32% ± 9% | |
| smooth muscle cell | 4 studies | 26% ± 5% | |
| duct epithelial cell | 3 studies | 32% ± 5% | |
| connective tissue cell | 3 studies | 32% ± 7% | |
| luminal cell of prostate epithelium | 3 studies | 30% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 13246.55 | 652 / 653 | 85% | 155.20 | 512 / 605 |
| lung | 100% | 40736.78 | 578 / 578 | 83% | 179.09 | 956 / 1155 |
| stomach | 82% | 6023.64 | 295 / 359 | 95% | 230.81 | 271 / 286 |
| breast | 85% | 2805.88 | 390 / 459 | 89% | 167.69 | 994 / 1118 |
| bladder | 95% | 4276.00 | 20 / 21 | 77% | 125.75 | 388 / 504 |
| intestine | 60% | 3999.89 | 584 / 966 | 97% | 226.44 | 513 / 527 |
| uterus | 68% | 1680.72 | 115 / 170 | 65% | 96.62 | 298 / 459 |
| ovary | 100% | 5100.66 | 180 / 180 | 33% | 22.96 | 140 / 430 |
| esophagus | 51% | 2011.43 | 740 / 1445 | 75% | 203.32 | 137 / 183 |
| pancreas | 12% | 180.12 | 39 / 328 | 88% | 263.70 | 157 / 178 |
| ureter | 0% | 0 | 0 / 0 | 100% | 411.39 | 1 / 1 |
| blood vessel | 92% | 5197.52 | 1231 / 1335 | 0% | 0 | 0 / 0 |
| kidney | 83% | 2365.53 | 74 / 89 | 8% | 8.96 | 76 / 901 |
| prostate | 68% | 2760.70 | 167 / 245 | 20% | 11.09 | 99 / 502 |
| skin | 65% | 1759.53 | 1177 / 1809 | 15% | 9.15 | 72 / 472 |
| adipose | 80% | 4806.27 | 964 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 36% | 585.00 | 94 / 258 | 6% | 2.51 | 13 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 38% | 27.59 | 17 / 45 |
| heart | 34% | 1573.90 | 294 / 861 | 0% | 0 | 0 / 0 |
| liver | 2% | 49.56 | 5 / 226 | 2% | 2.53 | 7 / 406 |
| brain | 2% | 42.59 | 54 / 2642 | 1% | 0.30 | 4 / 705 |
| peripheral blood | 2% | 29.97 | 16 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.79 | 1 / 80 |
| muscle | 0% | 9.18 | 4 / 803 | 0% | 0 | 0 / 0 |
| spleen | 0% | 5.32 | 1 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007165 | Biological process | signal transduction |
| GO_0007175 | Biological process | negative regulation of epidermal growth factor-activated receptor activity |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005730 | Cellular component | nucleolus |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0043235 | Cellular component | receptor complex |
| GO_0031982 | Cellular component | vesicle |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0030295 | Molecular function | protein kinase activator activity |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GPRC5A |
| Protein name | Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1) G protein-coupled receptor class C group 5 member A |
| Synonyms | RAI3 GPCR5A RAIG1 |
| Description | FUNCTION: Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling (By similarity). May act as a lung tumor suppressor . . |
| Accessions | A0A3B3ITN8 ENST00000540125.1 Q8NFJ5 ENST00000534831.1 ENST00000014914.6 H0YFN2 F5GWG3 ENST00000648791.1 |