SFTPA2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007585Biological processrespiratory gaseous exchange by respiratory system
GO_0045334Cellular componentclathrin-coated endocytic vesicle
GO_0005615Cellular componentextracellular space
GO_0005581Cellular componentcollagen trimer
GO_0005576Cellular componentextracellular region
GO_0042599Cellular componentlamellar body
GO_0005771Cellular componentmultivesicular body
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSFTPA2
Protein namePulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5)
Surfactant protein A2 variant ABD 1A (Surfactant protein A2 variant ABD' 1A)
Surfactant protein A2
SynonymsSFTP1
COLEC5
SFTPA2B
SFTPA
PSAP
DescriptionFUNCTION: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

AccessionsQ8IWL1
ENST00000640627.1
ENST00000492049.1
ENST00000417041.1
A0A1W2PR89
ENST00000372325.7
R4GMN3
X6REF7
ENST00000372327.9
E3VLD0