I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type II pneumocyte | 10 studies | 27% ± 6% | |
| type I pneumocyte | 8 studies | 22% ± 4% | |
| basal cell | 4 studies | 20% ± 3% | |
| ciliated cell | 3 studies | 23% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| type II pneumocyte | 10 studies | 27% ± 6% | |
| type I pneumocyte | 8 studies | 22% ± 4% | |
| basal cell | 4 studies | 20% ± 3% | |
| ciliated cell | 3 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of DUOXA1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 7822.30 | 651 / 653 | 92% | 73.65 | 555 / 605 |
| lung | 90% | 4541.47 | 518 / 578 | 68% | 11.75 | 781 / 1155 |
| esophagus | 39% | 3915.32 | 558 / 1445 | 74% | 22.39 | 136 / 183 |
| bladder | 48% | 1376.95 | 10 / 21 | 62% | 13.38 | 311 / 504 |
| prostate | 77% | 1411.27 | 189 / 245 | 27% | 2.25 | 134 / 502 |
| ureter | 0% | 0 | 0 / 0 | 100% | 17.89 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 30.54 | 43 / 45 |
| skin | 72% | 3152.82 | 1299 / 1809 | 10% | 1.68 | 46 / 472 |
| stomach | 70% | 1974.74 | 252 / 359 | 9% | 0.85 | 25 / 286 |
| uterus | 4% | 110.96 | 6 / 170 | 72% | 23.07 | 329 / 459 |
| pancreas | 0% | 2.01 | 1 / 328 | 38% | 4.52 | 68 / 178 |
| adrenal gland | 13% | 106.63 | 34 / 258 | 3% | 0.27 | 6 / 230 |
| intestine | 0% | 3.36 | 3 / 966 | 11% | 1.65 | 57 / 527 |
| breast | 0% | 2.78 | 2 / 459 | 11% | 1.07 | 118 / 1118 |
| ovary | 1% | 5.35 | 1 / 180 | 6% | 0.50 | 25 / 430 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.29 | 3 / 80 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.24 | 10 / 406 |
| kidney | 0% | 0 | 0 / 89 | 2% | 0.19 | 17 / 901 |
| brain | 0% | 0.96 | 3 / 2642 | 2% | 0.12 | 12 / 705 |
| adipose | 0% | 3.56 | 3 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 1.65 | 2 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 1.19 | 1 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 1.19 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_2000609 | Biological process | regulation of thyroid hormone generation |
| GO_0015031 | Biological process | protein transport |
| GO_0008104 | Biological process | protein localization |
| GO_0042743 | Biological process | hydrogen peroxide metabolic process |
| GO_0045666 | Biological process | positive regulation of neuron differentiation |
| GO_0050727 | Biological process | regulation of inflammatory response |
| GO_0010729 | Biological process | positive regulation of hydrogen peroxide biosynthetic process |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DUOXA1 |
| Protein name | Dual oxidase maturation factor 1 (Dual oxidase activator 1) (Numb-interacting protein) Dual oxidase maturation factor 1 gamma (Homolog of Drosophila Numb-interacting protein, isoform CRA_b) (cDNA FLJ76085, highly similar to Homo sapiens homolog of Drosophila Numb-interacting protein (NIP), mRNA) Dual oxidase maturation factor 1 alpha Dual oxidase maturation factor 1 Dual oxidase maturation factor 1 beta (Homolog of Drosophila Numb-interacting protein, isoform CRA_a) |
| Synonyms | NIP NUMBIP hCG_2036886 |
| Description | FUNCTION: May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1. . |
| Accessions | ENST00000558996.5 [Q1HG43-3] ENST00000559014.5 [Q1HG43-2] ENST00000430224.6 ENST00000558851.1 ENST00000559644.5 B5M0B8 H0YLQ4 ENST00000559226.5 ENST00000560572.6 [Q1HG43-1] ENST00000559013.5 H0YKF3 ENST00000558422.5 [Q1HG43-3] B5M0C0 H0YMH9 H0YMZ8 A8K9Q6 ENST00000558377.5 B5M0B7 H0YNR1 H0YLI1 ENST00000559988.5 Q1HG43 H0YKG3 ENST00000267803.8 [Q1HG43-2] ENST00000613425.4 ENST00000558326.5 |
