GO_0019370 | leukotriene biosynthetic process | OmnibusX

leukotriene biosynthetic process

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	PLA2G1B LTA4H MGST3	type II pneumocyte	8 studies
Group 2	ALOX5AP ALOX5 SYK MGST2	myeloid cell classical monocyte conventional dendritic cell dendritic cell	10 studies
Group 3	LTC4S	mast cell	31 studies
Group 4	PLA2G4A	microglial cell fibroblast macrophage Schwann cell	18 studies
Group 5	PLA2G5	fibroblast retinal cone cell pericyte retinal pigment epithelial cell smooth muscle cell	17 studies

II. Literature review

Name	leukotriene biosynthetic process
ID	GO_0019370
collection_id	Biological process
Exact synonym	leukotriene anabolism, leukotriene biosynthesis, leukotriene formation, leukotriene synthesis
Description	The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
External URL
Genes	ALOX5AP LTA4H ALOX5 PLA2G5 MGST2 PRG3 LTC4S PLA2G1B MGST3 PLA2G4A SYK