ALOX5AP report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	38 studies	49% ± 17%	Explore
B cell	31 studies	31% ± 14%	Explore
T cell	28 studies	34% ± 12%	Explore
mast cell	28 studies	66% ± 24%	Explore
CD8-positive, alpha-beta T cell	28 studies	42% ± 14%	Explore
macrophage	27 studies	47% ± 18%	Explore
plasmacytoid dendritic cell	27 studies	83% ± 16%	Explore
CD4-positive, alpha-beta T cell	26 studies	36% ± 14%	Explore
regulatory T cell	23 studies	32% ± 12%	Explore
mature NK T cell	21 studies	41% ± 18%	Explore
classical monocyte	21 studies	28% ± 9%	Explore
conventional dendritic cell	19 studies	42% ± 16%	Explore
gamma-delta T cell	17 studies	43% ± 15%	Explore
dendritic cell	16 studies	35% ± 17%	Explore
mucosal invariant T cell	16 studies	48% ± 14%	Explore
naive B cell	16 studies	27% ± 8%	Explore
memory B cell	15 studies	26% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	51% ± 13%	Explore
monocyte	14 studies	35% ± 16%	Explore
neutrophil	13 studies	52% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	26% ± 7%	Explore
myeloid cell	12 studies	49% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	41% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	39% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	52% ± 22%	Explore
microglial cell	10 studies	46% ± 27%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	35% ± 14%	Explore
leukocyte	9 studies	35% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	29% ± 11%	Explore
alveolar macrophage	8 studies	65% ± 30%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	44% ± 24%	Explore
innate lymphoid cell	7 studies	38% ± 13%	Explore
T follicular helper cell	7 studies	41% ± 10%	Explore
CD4-positive helper T cell	6 studies	39% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	37% ± 12%	Explore
mononuclear phagocyte	5 studies	26% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	53% ± 21%	Explore
exhausted T cell	4 studies	47% ± 19%	Explore
granulocyte	4 studies	66% ± 31%	Explore
monocyte-derived dendritic cell	4 studies	33% ± 11%	Explore
brush cell	4 studies	52% ± 19%	Explore
group 3 innate lymphoid cell	4 studies	43% ± 16%	Explore
T-helper 17 cell	4 studies	50% ± 10%	Explore
T-helper 1 cell	4 studies	48% ± 11%	Explore
Langerhans cell	3 studies	56% ± 14%	Explore
lymphocyte	3 studies	26% ± 5%	Explore
immature B cell	3 studies	39% ± 8%	Explore
tissue-resident macrophage	3 studies	32% ± 16%	Explore
intraepithelial lymphocyte	3 studies	58% ± 5%	Explore
germinal center B cell	3 studies	46% ± 10%	Explore
plasma cell	3 studies	35% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	39% ± 7%	Explore
double negative thymocyte	3 studies	32% ± 6%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	59% ± 14%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	29% ± 9%	Explore
lung	11 studies	28% ± 8%	Explore
lymph node	5 studies	36% ± 11%	Explore
bone marrow	4 studies	26% ± 9%	Explore
intestine	3 studies	26% ± 5%	Explore
brain	3 studies	47% ± 25%	Explore
liver	3 studies	46% ± 6%	Explore
uterus	3 studies	25% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	5427.67	578 / 578	94%	61.56	1083 / 1155
breast	85%	598.99	391 / 459	94%	40.20	1050 / 1118
intestine	85%	636.63	820 / 966	82%	29.77	434 / 527
stomach	75%	502.24	268 / 359	85%	37.38	243 / 286
bladder	90%	881.14	19 / 21	68%	28.06	343 / 504
esophagus	69%	449.40	1001 / 1445	78%	20.78	142 / 183
uterus	67%	434.71	114 / 170	76%	25.55	348 / 459
kidney	57%	399.60	51 / 89	83%	27.37	746 / 901
ovary	53%	339.71	96 / 180	85%	47.95	366 / 430
thymus	54%	290.30	350 / 653	85%	38.32	512 / 605
pancreas	45%	262.37	146 / 328	92%	81.00	164 / 178
prostate	77%	486.92	188 / 245	48%	7.91	242 / 502
brain	37%	303.88	972 / 2642	86%	75.61	607 / 705
adrenal gland	90%	989.14	231 / 258	21%	4.78	48 / 230
lymph node	0%	0	0 / 0	100%	194.60	29 / 29
spleen	100%	4954.88	241 / 241	0%	0	0 / 0
peripheral blood	99%	38000.88	917 / 929	0%	0	0 / 0
adipose	95%	1232.08	1140 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	39.50	42 / 45
blood vessel	88%	956.43	1170 / 1335	0%	0	0 / 0
skin	20%	77.82	358 / 1809	60%	20.00	285 / 472
liver	17%	89.39	38 / 226	26%	6.75	104 / 406
heart	39%	213.43	332 / 861	0%	0	0 / 0
muscle	3%	11.10	25 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.12	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1