FERD3L report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FERD3L at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FERD3L at tissue level.

III. Associated gene sets

GO_1904338Biological processregulation of dopaminergic neuron differentiation
GO_0050767Biological processregulation of neurogenesis
GO_0033504Biological processfloor plate development
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0048468Biological processcell development
GO_0032502Biological processdevelopmental process
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046983Molecular functionprotein dimerization activity
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameFERD3L
Protein nameFer3-like protein (Basic helix-loop-helix protein N-twist) (Class A basic helix-loop-helix protein 31) (bHLHa31) (Nephew of atonal 3) (Neuronal twist)
SynonymsNATO3
NTWIST
BHLHA31
DescriptionFUNCTION: Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins (By similarity). .

AccessionsENST00000275461.3
Q96RJ6