Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 20 studies | 29% ± 16% | |
| endothelial cell | 16 studies | 34% ± 17% | |
| astrocyte | 15 studies | 27% ± 13% | |
| fibroblast | 14 studies | 30% ± 13% | |
| type I pneumocyte | 12 studies | 37% ± 16% | |
| oligodendrocyte precursor cell | 12 studies | 39% ± 18% | |
| microglial cell | 11 studies | 41% ± 15% | |
| oligodendrocyte | 11 studies | 34% ± 14% | |
| mast cell | 10 studies | 23% ± 6% | |
| classical monocyte | 10 studies | 23% ± 9% | |
| pericyte | 10 studies | 30% ± 16% | |
| basal cell | 9 studies | 30% ± 20% | |
| glutamatergic neuron | 9 studies | 39% ± 26% | |
| myeloid cell | 9 studies | 32% ± 7% | |
| monocyte | 8 studies | 28% ± 9% | |
| epithelial cell | 8 studies | 33% ± 16% | |
| GABAergic neuron | 7 studies | 40% ± 19% | |
| dendritic cell | 7 studies | 34% ± 14% | |
| smooth muscle cell | 7 studies | 26% ± 7% | |
| non-classical monocyte | 6 studies | 30% ± 12% | |
| interneuron | 6 studies | 38% ± 25% | |
| adipocyte | 6 studies | 22% ± 6% | |
| type II pneumocyte | 6 studies | 29% ± 8% | |
| amacrine cell | 5 studies | 20% ± 3% | |
| retina horizontal cell | 5 studies | 28% ± 7% | |
| ciliated cell | 5 studies | 26% ± 7% | |
| endothelial cell of lymphatic vessel | 5 studies | 26% ± 8% | |
| neuron | 4 studies | 32% ± 20% | |
| granule cell | 4 studies | 29% ± 8% | |
| retinal ganglion cell | 4 studies | 30% ± 11% | |
| lymphocyte | 4 studies | 26% ± 5% | |
| abnormal cell | 4 studies | 32% ± 6% | |
| club cell | 4 studies | 35% ± 5% | |
| myofibroblast cell | 4 studies | 21% ± 6% | |
| natural killer cell | 3 studies | 16% ± 1% | |
| conventional dendritic cell | 3 studies | 26% ± 10% | |
| hematopoietic precursor cell | 3 studies | 19% ± 3% | |
| retinal pigment epithelial cell | 3 studies | 38% ± 20% | |
| Mueller cell | 3 studies | 18% ± 4% | |
| adventitial cell | 3 studies | 22% ± 4% | |
| T cell | 3 studies | 19% ± 5% | |
| alveolar macrophage | 3 studies | 37% ± 15% | |
| goblet cell | 3 studies | 36% ± 23% | |
| transit amplifying cell | 3 studies | 37% ± 31% | |
| mucus secreting cell | 3 studies | 24% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 12515.67 | 1445 / 1445 | 100% | 109.24 | 183 / 183 |
| prostate | 100% | 17050.75 | 245 / 245 | 100% | 56.12 | 500 / 502 |
| ovary | 100% | 19345.79 | 180 / 180 | 100% | 83.73 | 428 / 430 |
| thymus | 100% | 11862.22 | 653 / 653 | 99% | 41.69 | 601 / 605 |
| uterus | 100% | 18652.39 | 170 / 170 | 99% | 48.30 | 455 / 459 |
| intestine | 100% | 13609.09 | 966 / 966 | 99% | 57.69 | 522 / 527 |
| stomach | 100% | 9874.46 | 359 / 359 | 99% | 75.25 | 283 / 286 |
| pancreas | 100% | 7099.45 | 327 / 328 | 99% | 58.78 | 176 / 178 |
| skin | 100% | 14432.80 | 1809 / 1809 | 99% | 65.64 | 465 / 472 |
| breast | 100% | 14734.83 | 459 / 459 | 98% | 52.92 | 1101 / 1118 |
| adrenal gland | 100% | 13397.36 | 258 / 258 | 98% | 64.42 | 226 / 230 |
| brain | 99% | 9431.53 | 2611 / 2642 | 99% | 79.88 | 701 / 705 |
| lung | 100% | 18028.09 | 578 / 578 | 98% | 61.70 | 1132 / 1155 |
| kidney | 100% | 8324.03 | 89 / 89 | 97% | 44.07 | 871 / 901 |
| bladder | 100% | 14020.48 | 21 / 21 | 95% | 38.79 | 478 / 504 |
| liver | 92% | 3844.16 | 207 / 226 | 73% | 18.95 | 296 / 406 |
| adipose | 100% | 13019.81 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 13976.61 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 151.32 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 33.75 | 29 / 29 |
| muscle | 100% | 14997.07 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 9882.49 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 51.44 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.36 | 1 / 1 |
| heart | 99% | 9338.72 | 855 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 80% | 5954.71 | 745 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0044849 | Biological process | estrous cycle |
| GO_0032355 | Biological process | response to estradiol |
| GO_1902894 | Biological process | negative regulation of miRNA transcription |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0010243 | Biological process | response to organonitrogen compound |
| GO_0060766 | Biological process | negative regulation of androgen receptor signaling pathway |
| GO_0021549 | Biological process | cerebellum development |
| GO_0010565 | Biological process | regulation of cellular ketone metabolic process |
| GO_0007595 | Biological process | lactation |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0016020 | Cellular component | membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0017053 | Cellular component | transcription repressor complex |
| GO_0016363 | Cellular component | nuclear matrix |
| GO_0016604 | Cellular component | nuclear body |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0035259 | Molecular function | nuclear glucocorticoid receptor binding |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0005112 | Molecular function | Notch binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0046965 | Molecular function | nuclear retinoid X receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0042826 | Molecular function | histone deacetylase binding |
| Gene name | NCOR2 |
| Protein name | Nuclear receptor corepressor 2 Nuclear receptor corepressor 2 splice variant Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor) |
| Synonyms | CTG26 |
| Description | FUNCTION: Transcriptional corepressor . Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 4 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation . . |
| Accessions | H7C0P3 C9JQE8 C9J330 C9J0Q5 ENST00000420698.5 H7C1J7 ENST00000440187.5 ENST00000542927.5 ENST00000429285.6 A0A481PGK9 ENST00000404621.5 ENST00000448008.1 C9JNV9 C9JE98 H7C1Y3 H7C184 ENST00000453428.1 H7C2R5 ENST00000448614.1 ENST00000418829.5 ENST00000405201.6 [Q9Y618-1] Q9Y618 H0YGK8 ENST00000458234.5 ENST00000413172.1 H7BZU2 ENST00000440337.3 |