Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 24 studies | 30% ± 13% | |
| oligodendrocyte | 11 studies | 34% ± 17% | |
| macrophage | 11 studies | 31% ± 13% | |
| fibroblast | 10 studies | 27% ± 9% | |
| glutamatergic neuron | 8 studies | 40% ± 19% | |
| astrocyte | 8 studies | 34% ± 13% | |
| adipocyte | 8 studies | 25% ± 8% | |
| GABAergic neuron | 7 studies | 33% ± 17% | |
| microglial cell | 7 studies | 36% ± 11% | |
| pericyte | 7 studies | 30% ± 14% | |
| B cell | 7 studies | 27% ± 8% | |
| mast cell | 7 studies | 25% ± 9% | |
| T cell | 7 studies | 26% ± 7% | |
| natural killer cell | 6 studies | 24% ± 7% | |
| neuron | 6 studies | 39% ± 18% | |
| oligodendrocyte precursor cell | 6 studies | 37% ± 16% | |
| myeloid cell | 6 studies | 27% ± 11% | |
| epithelial cell | 6 studies | 37% ± 15% | |
| dendritic cell | 6 studies | 29% ± 4% | |
| endothelial cell of lymphatic vessel | 6 studies | 33% ± 11% | |
| smooth muscle cell | 6 studies | 26% ± 7% | |
| interneuron | 5 studies | 52% ± 19% | |
| retina horizontal cell | 5 studies | 19% ± 5% | |
| retinal cone cell | 5 studies | 21% ± 5% | |
| CD4-positive, alpha-beta T cell | 5 studies | 24% ± 5% | |
| CD8-positive, alpha-beta T cell | 5 studies | 21% ± 5% | |
| cardiac muscle cell | 5 studies | 29% ± 8% | |
| ciliated cell | 5 studies | 23% ± 7% | |
| monocyte | 5 studies | 33% ± 8% | |
| type I pneumocyte | 5 studies | 33% ± 9% | |
| type II pneumocyte | 5 studies | 31% ± 7% | |
| granule cell | 4 studies | 32% ± 9% | |
| amacrine cell | 4 studies | 24% ± 4% | |
| lymphocyte | 4 studies | 41% ± 16% | |
| retinal rod cell | 4 studies | 27% ± 6% | |
| club cell | 4 studies | 30% ± 9% | |
| naive B cell | 4 studies | 18% ± 2% | |
| basal cell | 4 studies | 30% ± 16% | |
| classical monocyte | 3 studies | 21% ± 3% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 25% ± 6% | |
| glial cell | 3 studies | 24% ± 7% | |
| progenitor cell | 3 studies | 28% ± 4% | |
| plasma cell | 3 studies | 31% ± 6% | |
| retinal bipolar neuron | 3 studies | 23% ± 6% | |
| mesothelial cell | 3 studies | 27% ± 7% | |
| mononuclear phagocyte | 3 studies | 24% ± 6% | |
| vein endothelial cell | 3 studies | 30% ± 17% | |
| GABAergic amacrine cell | 3 studies | 23% ± 4% | |
| Mueller cell | 3 studies | 21% ± 3% | |
| glycinergic amacrine cell | 3 studies | 24% ± 6% | |
| rod bipolar cell | 3 studies | 23% ± 5% | |
| endothelial cell of vascular tree | 3 studies | 32% ± 17% | |
| hepatocyte | 3 studies | 48% ± 20% | |
| retinal pigment epithelial cell | 3 studies | 31% ± 15% | |
| myofibroblast cell | 3 studies | 31% ± 11% | |
| alveolar macrophage | 3 studies | 35% ± 9% | |
| respiratory goblet cell | 3 studies | 28% ± 11% | |
| CD16-positive, CD56-dim natural killer cell, human | 3 studies | 20% ± 5% | |
| CD8-positive, alpha-beta memory T cell | 3 studies | 19% ± 3% | |
| plasmacytoid dendritic cell | 3 studies | 22% ± 5% | |
| mucus secreting cell | 3 studies | 24% ± 6% | |
| regulatory T cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3013.10 | 1445 / 1445 | 100% | 25.39 | 183 / 183 |
| brain | 100% | 3349.97 | 2639 / 2642 | 100% | 31.37 | 705 / 705 |
| ovary | 100% | 3965.52 | 180 / 180 | 100% | 28.22 | 429 / 430 |
| breast | 100% | 3877.44 | 459 / 459 | 100% | 29.41 | 1115 / 1118 |
| intestine | 100% | 3369.60 | 966 / 966 | 100% | 13.86 | 525 / 527 |
| skin | 100% | 3874.12 | 1809 / 1809 | 100% | 25.38 | 470 / 472 |
| uterus | 100% | 4411.39 | 170 / 170 | 100% | 18.59 | 457 / 459 |
| thymus | 100% | 3428.89 | 652 / 653 | 100% | 19.87 | 602 / 605 |
| stomach | 100% | 2206.58 | 359 / 359 | 99% | 16.86 | 284 / 286 |
| lung | 100% | 4544.20 | 578 / 578 | 99% | 19.63 | 1146 / 1155 |
| bladder | 100% | 3329.48 | 21 / 21 | 99% | 14.40 | 498 / 504 |
| prostate | 100% | 3127.70 | 245 / 245 | 99% | 13.87 | 496 / 502 |
| pancreas | 100% | 1529.89 | 328 / 328 | 98% | 14.04 | 175 / 178 |
| kidney | 100% | 2185.45 | 89 / 89 | 95% | 12.24 | 856 / 901 |
| adrenal gland | 100% | 2467.31 | 258 / 258 | 94% | 15.31 | 216 / 230 |
| liver | 100% | 1556.66 | 226 / 226 | 89% | 9.63 | 362 / 406 |
| adipose | 100% | 3466.98 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3543.83 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 18.50 | 29 / 29 |
| muscle | 100% | 3334.94 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3846.51 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 17.88 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.74 | 1 / 1 |
| peripheral blood | 99% | 4620.48 | 924 / 929 | 0% | 0 | 0 / 0 |
| heart | 99% | 2121.99 | 853 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 12.80 | 79 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0042659 | Biological process | regulation of cell fate specification |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_2000736 | Biological process | regulation of stem cell differentiation |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0016581 | Cellular component | NuRD complex |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0000781 | Cellular component | chromosome, telomeric region |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0031492 | Molecular function | nucleosomal DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| Gene name | GATAD2B |
| Protein name | Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68) GATA zinc finger domain containing 2B |
| Synonyms | KIAA1150 |
| Description | FUNCTION: Transcriptional repressor . Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin . Enhances MBD2-mediated repression . Efficient repression requires the presence of GATAD2A . Targets MBD3 to discrete loci in the nucleus . May play a role in synapse development . . |
| Accessions | ENST00000634564.1 ENST00000368655.5 ENST00000634408.1 ENST00000634791.1 ENST00000634544.1 Q8WXI9 ENST00000576342.2 A0A0U1RR30 A0A0U1RRK3 A0A994J4D5 A0A1B0GVS4 A0A1B0GW07 ENST00000637918.1 A0A0U1RRM1 ENST00000637331.1 ENST00000703630.1 ENST00000634401.1 A0A0U1RR34 |