GATAD2B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006338Biological processchromatin remodeling
GO_0042659Biological processregulation of cell fate specification
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_2000736Biological processregulation of stem cell differentiation
GO_0016607Cellular componentnuclear speck
GO_0016581Cellular componentNuRD complex
GO_0032991Cellular componentprotein-containing complex
GO_0000781Cellular componentchromosome, telomeric region
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0031492Molecular functionnucleosomal DNA binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0043565Molecular functionsequence-specific DNA binding

IV. Literature review

[source]
Gene nameGATAD2B
Protein nameTranscriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68)
GATA zinc finger domain containing 2B
SynonymsKIAA1150
DescriptionFUNCTION: Transcriptional repressor . Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin . Enhances MBD2-mediated repression . Efficient repression requires the presence of GATAD2A . Targets MBD3 to discrete loci in the nucleus . May play a role in synapse development . .

AccessionsENST00000634564.1
ENST00000368655.5
ENST00000634408.1
ENST00000634791.1
ENST00000634544.1
Q8WXI9
ENST00000576342.2
A0A0U1RR30
A0A0U1RRK3
A0A994J4D5
A0A1B0GVS4
A0A1B0GW07
ENST00000637918.1
A0A0U1RRM1
ENST00000637331.1
ENST00000703630.1
ENST00000634401.1
A0A0U1RR34