Name | chromosome, telomeric region |
ID | GO_0000781 |
collection_id | Cellular component |
Alternative ID | GO:0000784 |
Description | The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). |
Related synonym | telomere |
Comment | Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. |
External URL | |
Genes | NAT10THOC1ALYREFATMORC4TERF2IPRAD51DPARP1MCM5URS00004416C5_9606PMLLIG4SIRT2XRCC6H4C1H2BC1SMC6MRE11WRNRAD51AP1CHEK2H3-3APPP1CBTEP1SMCHD1NHP2THOC3RNF8LRWD1TNKSRPA1ZBTB10MCM4MACROH2A2PPP1CAATRRPA2EZH2SP100WRAP53BLMKDM1ATERTORC5ZSCAN4NABP1POLD1SPDYATEN1NABP2TERF2TINF2smc5-smc6_humanH2AXORC1FEN1TFIP11slx4-terf2_humanTOX4ORC3CBX3NBNATRXPURASLF2TERB1ERCC4TELO2ZNF827XRCC5XRCC1SPO11ercc1-xpf_humanDHX36KASH5STN1PPP1CCSMG6RBBP7smc5-smc6_human-1CBX1TERB2SETXACDPIF1EZH1THOC2PTGES3RBBP4WRNIP1ZBTB48THOC5CTC1HAT1GAR1ATF7NSMCE1MACROH2A1THOC6MCM2DDB1POT1RPA4RTEL1HDAC2TERF1H2BW1CHEK1SUN1PRKDCPCNAEID3MCM3MEN1SUN2RECQL4WDR82POLR2BMAJINMCM6NLRP2HMBOX1MTA2RAD17ORC2DNA2H2BC3MSH2URS00004A7003_9606CBX5GATAD2BRAD50H2AC1APEX1TP53BP1NSMCE2CHD4TNKS2MCM7SMC5LRIF1H3-4CDC73HNRNPA2B1SLX4NSMCE3DCLRE1BDMC1RAD51PPP1R10BRCA2CDK2XRCC3TRIOBPSLF1THOC7CDK1NSMCE4AUPF1ERCC1SSBPINX1 |