Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 12 studies | 26% ± 9% | |
lung | 9 studies | 30% ± 17% | |
eye | 5 studies | 28% ± 12% | |
bone marrow | 5 studies | 18% ± 1% | |
liver | 5 studies | 28% ± 21% | |
pancreas | 4 studies | 38% ± 12% | |
brain | 4 studies | 32% ± 11% | |
intestine | 4 studies | 25% ± 11% | |
kidney | 3 studies | 17% ± 1% | |
placenta | 3 studies | 23% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2183.81 | 21 / 21 | 100% | 98.53 | 504 / 504 |
esophagus | 100% | 2509.73 | 1445 / 1445 | 100% | 60.82 | 183 / 183 |
ovary | 100% | 1519.32 | 180 / 180 | 100% | 87.41 | 430 / 430 |
pancreas | 100% | 1328.39 | 328 / 328 | 100% | 73.59 | 178 / 178 |
prostate | 100% | 1698.64 | 245 / 245 | 100% | 81.95 | 502 / 502 |
stomach | 100% | 1513.00 | 359 / 359 | 100% | 88.11 | 286 / 286 |
uterus | 100% | 1817.49 | 170 / 170 | 100% | 103.39 | 459 / 459 |
brain | 100% | 2152.73 | 2640 / 2642 | 100% | 61.15 | 705 / 705 |
breast | 100% | 2016.56 | 459 / 459 | 100% | 95.52 | 1117 / 1118 |
thymus | 100% | 1350.64 | 653 / 653 | 100% | 69.12 | 604 / 605 |
intestine | 100% | 2340.57 | 966 / 966 | 100% | 98.79 | 526 / 527 |
kidney | 100% | 1721.64 | 89 / 89 | 100% | 61.57 | 899 / 901 |
lung | 100% | 1551.53 | 576 / 578 | 100% | 76.36 | 1155 / 1155 |
adrenal gland | 100% | 1970.39 | 258 / 258 | 100% | 66.72 | 229 / 230 |
liver | 100% | 925.84 | 225 / 226 | 100% | 57.56 | 406 / 406 |
skin | 100% | 2214.58 | 1808 / 1809 | 99% | 83.47 | 468 / 472 |
lymph node | 0% | 0 | 0 / 0 | 100% | 137.90 | 29 / 29 |
muscle | 100% | 2457.97 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1282.04 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 85.78 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 53.76 | 1 / 1 |
blood vessel | 100% | 2384.52 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 2113.85 | 1203 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 1863.53 | 846 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 40.30 | 73 / 80 |
peripheral blood | 89% | 1422.23 | 826 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006406 | Biological process | mRNA export from nucleus |
GO_0008380 | Biological process | RNA splicing |
GO_0006397 | Biological process | mRNA processing |
GO_0016607 | Cellular component | nuclear speck |
GO_0000445 | Cellular component | THO complex part of transcription export complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000346 | Cellular component | transcription export complex |
GO_0000347 | Cellular component | THO complex |
GO_0000781 | Cellular component | chromosome, telomeric region |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | THOC7 |
Protein name | THO complex subunit 7 THO complex subunit 7 homolog THO complex subunit 7 homolog (Functional spliceosome-associated protein 24) (fSAP24) (Ngg1-interacting factor 3-like protein 1-binding protein 1) (NIF3L1-binding protein 1) (hTREX30) |
Synonyms | NIF3L1BP1 hCG_23514 |
Description | FUNCTION: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. .; FUNCTION: The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. . FUNCTION: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. . |
Accessions | H7C5E3 ENST00000469153.5 ENST00000295899.10 Q6I9Y2 A0A5S6STF9 ENST00000464327.2 ENST00000469584.5 F8WF22 |