intestinal crypt stem cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
LEFTY1539% ± 14%01
RNF186421% ± 5%02
UGT2B17434% ± 8%03
VDR324% ± 8%01
SPR316% ± 0%02
OLFM4658% ± 21%15
KRTCAP3528% ± 7%19
DEFA6420% ± 4%11
ALDH1B1430% ± 11%12
KLK1430% ± 19%13
DEFA5436% ± 17%13
CCL25451% ± 10%14
CLDN15427% ± 6%15
GPR15LG432% ± 9%15
REG1A459% ± 8%16
FAM3B432% ± 9%112
GJB1319% ± 2%12
TRUB2317% ± 1%12
PPP1R1B642% ± 19%27
CDX2530% ± 9%25
RGMB535% ± 18%25
URAD422% ± 2%24
CDX1437% ± 13%26
PIGR567% ± 29%217
SLC39A5426% ± 6%27
HMGCS2636% ± 12%38
GPX2658% ± 23%311
ASCL2540% ± 18%36
CDCA7540% ± 13%311
SPINK1658% ± 32%412

III. Associated gene sets

GO_0035377Biological processtransepithelial water transport
GO_0071636Biological processpositive regulation of transforming growth factor beta production
GO_0006739Biological processNADP metabolic process
GO_0045730Biological processrespiratory burst
GO_0042743Biological processhydrogen peroxide metabolic process
GO_0045726Biological processpositive regulation of integrin biosynthetic process
GO_0043278Biological processresponse to morphine
GO_0003081Biological processregulation of systemic arterial blood pressure by renin-angiotensin
GO_0090187Biological processpositive regulation of pancreatic juice secretion
GO_0060046Biological processregulation of acrosome reaction
GO_0010626Biological processnegative regulation of Schwann cell proliferation
GO_0090277Biological processpositive regulation of peptide hormone secretion
GO_0006207Biological process'de novo' pyrimidine nucleobase biosynthetic process
GO_0051673Biological processdisruption of plasma membrane integrity in another organism
GO_0097647Biological processamylin receptor signaling pathway
GO_0060711Biological processlabyrinthine layer development
GO_0061470Biological processT follicular helper cell differentiation
GO_0071375Biological processcellular response to peptide hormone stimulus
GO_0050667Biological processhomocysteine metabolic process
GO_0071455Biological processcellular response to hyperoxia
GO_1903237Biological processnegative regulation of leukocyte tethering or rolling
GO_1902177Biological processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO_0072592Biological processoxygen metabolic process
GO_0045626Biological processnegative regulation of T-helper 1 cell differentiation
GO_0046209Biological processnitric oxide metabolic process
GO_0051873Biological processkilling by host of symbiont cells
GO_0019240Biological processcitrulline biosynthetic process

IV. Literature review

[source]
Cell type nameintestinal crypt stem cell
Synonymsstem cell of intestinal crypt of Lieberkuhn
DescriptionA cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells.
ParentCL_0000048