GPX2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0098869Biological processcellular oxidant detoxification
GO_0006979Biological processresponse to oxidative stress
GO_0005829Cellular componentcytosol
GO_0072686Cellular componentmitotic spindle
GO_0005737Cellular componentcytoplasm
GO_0045171Cellular componentintercellular bridge
GO_0047066Molecular functionphospholipid-hydroperoxide glutathione peroxidase activity
GO_0004602Molecular functionglutathione peroxidase activity
GO_0009055Molecular functionelectron transfer activity

IV. Literature review

[source]
Gene nameGPX2
Protein nameGlutathione peroxidase
glutathione peroxidase (EC 1.11.1.9)
Glutathione peroxidase 2 (GPx-2) (GSHPx-2) (EC 1.11.1.9) (Gastrointestinal glutathione peroxidase) (Glutathione peroxidase-gastrointestinal) (GPx-GI) (GSHPx-GI) (Glutathione peroxidase-related protein 2) (GPRP-2) (Phospholipid hydroperoxide glutathione peroxidase GPX2) (EC 1.11.1.12)
Synonyms
DescriptionFUNCTION: Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis . Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides . Cannot reduce phosphatidycholine hydroperoxide . .

AccessionsG3V323
ENST00000389614.6
ENST00000553522.1
ENST00000557049.1
H0YJK8
P18283
G3V4J6
ENST00000557323.1