LEFTY1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
intestinal crypt stem cell	5 studies	39% ± 14%	Explore
transit amplifying cell	4 studies	27% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
intestine	3 studies	18% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	2345.25	328 / 328	66%	24.06	118 / 178
intestine	95%	2240.67	918 / 966	68%	69.64	360 / 527
stomach	83%	73.16	299 / 359	48%	40.24	136 / 286
ovary	96%	273.87	173 / 180	10%	1.85	42 / 430
brain	99%	133.17	2606 / 2642	3%	0.08	21 / 705
uterus	87%	51.86	148 / 170	14%	7.56	64 / 459
prostate	96%	73.51	235 / 245	4%	0.11	18 / 502
bladder	76%	91.90	16 / 21	23%	22.42	117 / 504
kidney	81%	102.75	72 / 89	15%	5.14	133 / 901
blood vessel	89%	42.77	1191 / 1335	0%	0	0 / 0
liver	71%	30.20	161 / 226	12%	1.49	50 / 406
spleen	72%	24.18	174 / 241	0%	0	0 / 0
esophagus	57%	26.13	819 / 1445	15%	3.14	28 / 183
lung	61%	25.75	355 / 578	6%	2.03	73 / 1155
breast	64%	27.47	295 / 459	2%	0.24	20 / 1118
adipose	61%	20.61	735 / 1204	0%	0	0 / 0
adrenal gland	54%	15.19	140 / 258	0%	0	0 / 230
muscle	52%	16.82	417 / 803	0%	0	0 / 0
heart	43%	13.05	373 / 861	0%	0	0 / 0
thymus	36%	9.64	232 / 653	0%	0	0 / 605
peripheral blood	34%	11.23	314 / 929	0%	0	0 / 0
skin	31%	8.77	563 / 1809	0%	0	0 / 472
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1