GO_0005125 | OmnibusX

cytokine activity

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	TNFSF10-TNFRSF11B	TNF10_HUMAN - TR11B_HUMAN	Ligand-Receptor	Signaling by Tumor necrosis factor
2	TNFSF11-TNFRSF11B	TNF11_HUMAN - TR11B_HUMAN	Ligand-Receptor	Signaling by Tumor necrosis factor
3	WNT1-CER1	WNT1_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
4	WNT11-CER1	WNT11_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
5	WNT16-CER1	WNT16_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
6	WNT2-CER1	WNT2_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
7	WNT2B-CER1	WNT2B_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
8	WNT3-CER1	WNT3_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
9	WNT3A-CER1	WNT3A_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
10	WNT4-CER1	WNT4_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
11	WNT5A-CER1	WNT5A_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
12	WNT5B-CER1	WNT5B_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
13	WNT6-CER1	WNT6_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
14	WNT7A-CER1	WNT7A_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
15	WNT7B-CER1	WNT7B_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
16	WNT8A-CER1	WNT8A_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
17	WNT8B-CER1	WNT8B_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
18	WNT9A-CER1	WNT9A_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
19	WNT9B-CER1	WNT9B_HUMAN - CER1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition

II. Literature review

Name	cytokine activity
ID	GO_0005125
collection_id	Molecular function
Description	The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells.
Related synonym	autocrine activity, paracrine activity
External URL
Genes	GREM2 THPO INHBE GDF6 BMP5 interleukin12_human IFNA17 IL1B NRG1 MSMP IFNA21 LEFTY1 IFNA4 OSM IL19 CXCL9 IL1F10 WNT6 FAM3C INHBA WNT9B BMP15 TNFSF8 interleukin-23_human BMP7 TSLP IFNA6 IFNK AIMP1 GRN KITLG IL17C IL1A IL27 IL36RN IFNG TNFSF13B IL11 TNFSF4 WNT2 EBI3 TNFSF12 IL21 IFNA5 IL24 BMP6 WNT8B IL36G IFNL1 CMTM7 IFNA8 FGF2 TNFRSF11B LIF THNSL2 IL33 GPI IFNL4 IFNA2 CTF1 TNFSF13 TGFB3 IL9 CMTM2 GDF10 WNT16 WNT2B TNFSF10 IFNL2 GREM1 FAM3D WNT8A ALKAL1 IL34 NDP TGFB1 WNT11 IL23A WNT3 IFNB1 IFNA16 WNT9A BMP2 TGFB2 SCG2 NAMPT C17orf99 INHBC IL2 FAM3B IL3 IL1RN WNT7A TAFA5 WNT1 TNFSF14 CMTM8 VSTM1 IL32 GDF11 GDF2 IL17A CRLF1 HMGB1 CER1 CSF2 BMP8A ALKAL2 WNT10A IL17B MIF FLT3LG IFNW1 WNT4 TNFSF15 LTA CLCF1 GDF3 SECTM1 SLURP1 IL22 IL17D IL25 WNT5A CSF1 IFNA14 CSF3 GDF7 LEFTY2 IL4 CMTM5 VEGFA WNT7B BMP4 IL18 IFNA10 IL13 IL16 IFNL3 IL20 GDF5 IFNE WNT10B IL15 C1QTNF4 FASLG WNT3A MSTN CD40LG AREG IL26 CMTM1 ADIPOQ WNT5B GDF9 BMP10 IL31 LTB TNFSF11 SCGB3A1 BMP3 INHBB IL36B IL5 CMTM3 IL37 INHA TNF TNFSF9 EPO EDN1 IL10 IL36A IL6 IL12B TNFSF18 CCL4 TIMP1 NODAL IFNA1 GDF15 CNTF GH1 SPP1 GDF1 BMP1 IL12A BMP8B IL17F IL7 EDA ifngamma_human IFNA7