I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 22% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 22% ± 7% |
Insufficient scRNA-seq data for expression of WNT10B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 78% | 1353.67 | 2066 / 2642 | 57% | 3.69 | 399 / 705 |
| lung | 69% | 104.92 | 399 / 578 | 48% | 2.37 | 549 / 1155 |
| esophagus | 63% | 117.25 | 916 / 1445 | 44% | 2.19 | 80 / 183 |
| skin | 67% | 178.47 | 1220 / 1809 | 38% | 1.51 | 179 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.22 | 1 / 1 |
| spleen | 100% | 416.47 | 240 / 241 | 0% | 0 | 0 / 0 |
| prostate | 52% | 73.62 | 127 / 245 | 43% | 0.88 | 216 / 502 |
| thymus | 57% | 98.30 | 374 / 653 | 24% | 1.84 | 147 / 605 |
| intestine | 54% | 158.40 | 522 / 966 | 25% | 1.00 | 131 / 527 |
| stomach | 51% | 67.19 | 182 / 359 | 24% | 0.83 | 69 / 286 |
| bladder | 48% | 116.14 | 10 / 21 | 26% | 0.97 | 133 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 73% | 6.77 | 33 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 2.13 | 20 / 29 |
| peripheral blood | 67% | 178.46 | 619 / 929 | 0% | 0 | 0 / 0 |
| uterus | 11% | 12.84 | 18 / 170 | 56% | 2.61 | 255 / 459 |
| breast | 39% | 52.97 | 180 / 459 | 24% | 0.70 | 272 / 1118 |
| adipose | 49% | 100.17 | 592 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 1% | 1.04 | 3 / 328 | 36% | 0.77 | 64 / 178 |
| kidney | 16% | 26.63 | 14 / 89 | 16% | 0.38 | 144 / 901 |
| heart | 30% | 51.16 | 257 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 22% | 37.20 | 290 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 13% | 0.19 | 10 / 80 |
| adrenal gland | 2% | 1.68 | 5 / 258 | 10% | 2.23 | 22 / 230 |
| liver | 3% | 2.45 | 6 / 226 | 9% | 0.23 | 35 / 406 |
| ovary | 3% | 7.81 | 6 / 180 | 7% | 0.15 | 31 / 430 |
| muscle | 2% | 4.60 | 19 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0071300 | Biological process | cellular response to retinoic acid |
| GO_0060346 | Biological process | bone trabecula formation |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0032434 | Biological process | regulation of proteasomal ubiquitin-dependent protein catabolic process |
| GO_0007224 | Biological process | smoothened signaling pathway |
| GO_0010971 | Biological process | positive regulation of G2/M transition of mitotic cell cycle |
| GO_0045444 | Biological process | fat cell differentiation |
| GO_0045582 | Biological process | positive regulation of T cell differentiation |
| GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
| GO_0014835 | Biological process | myoblast differentiation involved in skeletal muscle regeneration |
| GO_0030855 | Biological process | epithelial cell differentiation |
| GO_1902035 | Biological process | positive regulation of hematopoietic stem cell proliferation |
| GO_0001649 | Biological process | osteoblast differentiation |
| GO_0048741 | Biological process | skeletal muscle fiber development |
| GO_0002062 | Biological process | chondrocyte differentiation |
| GO_0045899 | Biological process | positive regulation of RNA polymerase II transcription preinitiation complex assembly |
| GO_0045599 | Biological process | negative regulation of fat cell differentiation |
| GO_0071374 | Biological process | cellular response to parathyroid hormone stimulus |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045669 | Biological process | positive regulation of osteoblast differentiation |
| GO_0071425 | Biological process | hematopoietic stem cell proliferation |
| GO_0050680 | Biological process | negative regulation of epithelial cell proliferation |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_0050909 | Biological process | sensory perception of taste |
| GO_0030217 | Biological process | T cell differentiation |
| GO_0030182 | Biological process | neuron differentiation |
| GO_0071320 | Biological process | cellular response to cAMP |
| GO_0045165 | Biological process | cell fate commitment |
| GO_0061196 | Biological process | fungiform papilla development |
| GO_0048641 | Biological process | regulation of skeletal muscle tissue development |
| GO_0050821 | Biological process | protein stabilization |
| GO_0000086 | Biological process | G2/M transition of mitotic cell cycle |
| GO_0048627 | Biological process | myoblast development |
| GO_0051885 | Biological process | positive regulation of timing of anagen |
| GO_0006629 | Biological process | lipid metabolic process |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0030501 | Biological process | positive regulation of bone mineralization |
| GO_0120163 | Biological process | negative regulation of cold-induced thermogenesis |
| GO_0030858 | Biological process | positive regulation of epithelial cell differentiation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0048018 | Molecular function | receptor ligand activity |
| GO_0005109 | Molecular function | frizzled binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | WNT10B |
| Protein name | Protein Wnt-10b (Protein Wnt-12) Protein Wnt |
| Synonyms | WNT12 |
| Description | FUNCTION: Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . |
| Accessions | ENST00000420388.1 C9JCI2 ENST00000301061.9 [O00744-1] ENST00000403957.5 C9J3H3 O00744 ENST00000407467.5 [O00744-2] ENST00000413630.1 B5MCC8 |
