Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | DHH-BOC+PTCH1 | DHH_HUMAN - | Ligand-Receptor | Signaling by Desert hedgehog |
| 2 | DHH-CDON+PTCH1 | DHH_HUMAN - | Ligand-Receptor | Signaling by Desert hedgehog |
| 3 | DHH-GAS1+PTCH1 | DHH_HUMAN - | Ligand-Receptor | Signaling by Desert hedgehog |
| 4 | IHH-BOC+PTCH1 | IHH_HUMAN - | Ligand-Receptor | Signaling by Indian hedgehog |
| 5 | IHH-CDON+PTCH1 | IHH_HUMAN - | Ligand-Receptor | Signaling by Indian hedgehog |
| 6 | IHH-GAS1+PTCH1 | IHH_HUMAN - | Ligand-Receptor | Signaling by Indian hedgehog |
| 7 | SHH-BOC+PTCH1 | SHH_HUMAN - | Ligand-Receptor | Signaling by Sonic hedgehog |
| 8 | SHH-CDON+PTCH1 | SHH_HUMAN - | Ligand-Receptor | Signaling by Sonic hedgehog |
| 9 | SHH-CDON+PTCH2 | SHH_HUMAN - | Ligand-Receptor | Signaling by Sonic hedgehog |
| 10 | SHH-GAS1+PTCH1 | SHH_HUMAN - | Ligand-Receptor | Signaling by Sonic hedgehog |
| Name | smoothened signaling pathway |
| ID | GO_0007224 |
| collection_id | Biological process |
| Exact synonym | hedgehog signaling pathway, smoothened signalling pathway |
| Description | The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. |
| Related synonym | Shh signaling pathway |
| External URL | |
| Genes | B9D1TTC21BIFT172STK36CENPJCC2D2ASHHIFT57NKX6-1IFT80TMEM231WDPCPIQUBIFT52PDX1FOXF1DISP1DISP3STILFGF9DZIP1LIFT56SHOX2RUNX2PRRX1IFT25GPR37L1CFAP410TCTN3PTCH1CPLANE2PAX6BBS7HHATGPC2NDPEVC2CTNNA1FOXA1HIPK2GPC3HSPG2EVCTCTN2PTCHD1FKBP8TUBA1ACD3EGLI3DISP2MAP3K10SKOR2GLI2IFT20IFT27NSDHLGLI1SEPTIN2DZIP1TMEM17DYRK2ZIC3HES5WNT10BNOGTTBK2RB1INTUTGFBR2ARL13BIHHNKX2-2CLUAP1SMODHHRO60ARL3HIPK1PKD2L1ULK3HES1KIAA0586CDON |