I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 4 studies | 21% ± 7% | |
| astrocyte | 3 studies | 33% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 4 studies | 21% ± 7% | |
| astrocyte | 3 studies | 33% ± 11% |
Insufficient scRNA-seq data for expression of EVC2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 948.03 | 653 / 653 | 99% | 6.97 | 597 / 605 |
| ovary | 100% | 1673.49 | 180 / 180 | 97% | 4.70 | 415 / 430 |
| kidney | 100% | 523.62 | 89 / 89 | 95% | 5.88 | 853 / 901 |
| skin | 100% | 917.08 | 1809 / 1809 | 86% | 6.49 | 404 / 472 |
| breast | 100% | 886.15 | 458 / 459 | 85% | 2.92 | 946 / 1118 |
| prostate | 100% | 786.55 | 245 / 245 | 84% | 2.57 | 421 / 502 |
| lung | 99% | 498.88 | 573 / 578 | 84% | 3.51 | 968 / 1155 |
| uterus | 100% | 1298.98 | 170 / 170 | 78% | 4.73 | 359 / 459 |
| pancreas | 81% | 199.31 | 267 / 328 | 88% | 3.66 | 157 / 178 |
| esophagus | 100% | 771.00 | 1444 / 1445 | 60% | 2.55 | 110 / 183 |
| bladder | 100% | 935.19 | 21 / 21 | 56% | 2.34 | 282 / 504 |
| intestine | 96% | 642.27 | 928 / 966 | 34% | 0.88 | 179 / 527 |
| stomach | 82% | 403.06 | 296 / 359 | 47% | 1.14 | 135 / 286 |
| adipose | 100% | 1024.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1002.93 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 4.31 | 79 / 80 |
| spleen | 87% | 213.68 | 209 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 3.61 | 39 / 45 |
| adrenal gland | 57% | 117.83 | 147 / 258 | 29% | 0.63 | 66 / 230 |
| heart | 83% | 340.63 | 716 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 4.80 | 21 / 29 |
| liver | 23% | 42.90 | 52 / 226 | 40% | 1.86 | 164 / 406 |
| brain | 14% | 28.16 | 358 / 2642 | 36% | 1.50 | 254 / 705 |
| muscle | 48% | 110.75 | 382 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 7% | 27.88 | 69 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007224 | Biological process | smoothened signaling pathway |
| GO_0060170 | Cellular component | ciliary membrane |
| GO_0005929 | Cellular component | cilium |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0098797 | Cellular component | plasma membrane protein complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| Gene name | EVC2 |
| Protein name | Ellis van Creveld syndrome 2 (Limbin), isoform CRA_c (EvC ciliary complex subunit 2) Limbin (Ellis-van Creveld syndrome protein 2) (EVC2) Uncharacterized protein EVC2 EvC ciliary complex subunit 2 Ellis van Creveld syndrome 2 protein |
| Synonyms | hCG_1981074 LBN |
| Description | FUNCTION: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryonic morphogenesis. . |
| Accessions | ENST00000310917.6 [Q86UK5-2] ENST00000475313.5 ENST00000509670.1 ENST00000344408.10 [Q86UK5-1] E9PFT2 A0A0A0RAS4 A0A0C4DGE7 Q4W5B1 Q4W5A4 Q86UK5 |
