CPLANE2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CPLANE2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CPLANE2 at tissue level.

III. Associated gene sets

GO_0008589Biological processregulation of smoothened signaling pathway
GO_0060271Biological processcilium assembly
GO_1904888Biological processcranial skeletal system development
GO_0007224Biological processsmoothened signaling pathway
GO_0031338Biological processregulation of vesicle fusion
GO_0060173Biological processlimb development
GO_0016485Biological processprotein processing
GO_0017157Biological processregulation of exocytosis
GO_0006887Biological processexocytosis
GO_0035082Biological processaxoneme assembly
GO_0015031Biological processprotein transport
GO_0008104Biological processprotein localization
GO_0003274Biological processendocardial cushion fusion
GO_0005814Cellular componentcentriole
GO_0035869Cellular componentciliary transition zone
GO_0005737Cellular componentcytoplasm
GO_0097546Cellular componentciliary base
GO_0036064Cellular componentciliary basal body
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameCPLANE2
Protein nameCiliogenesis and planar polarity effector complex subunit 2
Ciliogenesis and planar polarity effector 2 (REM2- and Rab-like small GTPase 1)
SynonymsC1orf89
RSG1
DescriptionFUNCTION: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity). .

AccessionsH0Y6L8
ENST00000434014.1
ENST00000375599.8
Q9BU20
ENST00000707390.1