Insufficient scRNA-seq data for expression of SKOR2 at single-cell level.
Insufficient scRNA-seq data for expression of SKOR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 18% | 12.21 | 473 / 2642 | 21% | 0.93 | 146 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.70 | 2 / 29 |
| thymus | 0% | 0 | 0 / 653 | 6% | 0.32 | 39 / 605 |
| adrenal gland | 0% | 0 | 0 / 258 | 3% | 0.32 | 6 / 230 |
| lung | 0% | 0 | 0 / 578 | 2% | 0.09 | 21 / 1155 |
| esophagus | 0% | 0 | 0 / 1445 | 2% | 0.04 | 3 / 183 |
| ovary | 0% | 0 | 0 / 180 | 1% | 0.04 | 6 / 430 |
| prostate | 0% | 0.10 | 1 / 245 | 0% | 0.01 | 1 / 502 |
| skin | 0% | 0.01 | 1 / 1809 | 0% | 0.01 | 2 / 472 |
| uterus | 0% | 0 | 0 / 170 | 0% | 0.04 | 2 / 459 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0.02 | 2 / 504 |
| intestine | 0% | 0 | 0 / 966 | 0% | 0.01 | 2 / 527 |
| stomach | 0% | 0 | 0 / 359 | 0% | 0.01 | 1 / 286 |
| breast | 0% | 0 | 0 / 459 | 0% | 0.00 | 2 / 1118 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 1 / 901 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 0% | 0 | 0 / 178 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007224 | Biological process | smoothened signaling pathway |
| GO_0021702 | Biological process | cerebellar Purkinje cell differentiation |
| GO_0030512 | Biological process | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO_0048814 | Biological process | regulation of dendrite morphogenesis |
| GO_0030514 | Biological process | negative regulation of BMP signaling pathway |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_1902692 | Biological process | regulation of neuroblast proliferation |
| GO_0045880 | Biological process | positive regulation of smoothened signaling pathway |
| GO_0021936 | Biological process | regulation of cerebellar granule cell precursor proliferation |
| GO_0048468 | Biological process | cell development |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0003682 | Molecular function | chromatin binding |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0046332 | Molecular function | SMAD binding |
| GO_0042826 | Molecular function | histone deacetylase binding |
| Gene name | SKOR2 |
| Protein name | SKI family transcriptional corepressor 2 (Functional Smad-suppressing element on chromosome 18) (Fussel-18) (LBX1 corepressor 1-like protein) (Ladybird homeobox corepressor 1-like protein) |
| Synonyms | CORL2 FUSSEL18 |
| Description | FUNCTION: Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system. . |
| Accessions | ENST00000425639.3 [Q2VWA4-1] ENST00000400404.1 [Q2VWA4-2] Q2VWA4 ENST00000620245.4 [Q2VWA4-1] |