Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 16 studies | 32% ± 11% | |
glutamatergic neuron | 3 studies | 28% ± 2% | |
astrocyte | 3 studies | 25% ± 9% |
Insufficient scRNA-seq data for expression of IQUB at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 157.00 | 89 / 89 | 68% | 1.86 | 613 / 901 |
thymus | 100% | 199.86 | 653 / 653 | 68% | 1.64 | 411 / 605 |
prostate | 96% | 50.31 | 234 / 245 | 17% | 0.31 | 83 / 502 |
adrenal gland | 96% | 64.76 | 248 / 258 | 10% | 0.17 | 23 / 230 |
uterus | 98% | 96.32 | 166 / 170 | 6% | 0.16 | 28 / 459 |
ovary | 93% | 43.97 | 168 / 180 | 10% | 0.21 | 42 / 430 |
breast | 85% | 59.92 | 389 / 459 | 16% | 0.35 | 183 / 1118 |
lung | 91% | 101.47 | 528 / 578 | 8% | 0.20 | 94 / 1155 |
bladder | 90% | 31.67 | 19 / 21 | 1% | 0.01 | 5 / 504 |
brain | 75% | 34.85 | 1983 / 2642 | 15% | 0.35 | 105 / 705 |
blood vessel | 75% | 21.67 | 995 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 70% | 19.66 | 228 / 328 | 4% | 0.06 | 7 / 178 |
adipose | 69% | 21.71 | 832 / 1204 | 0% | 0 | 0 / 0 |
esophagus | 65% | 102.61 | 938 / 1445 | 3% | 0.05 | 5 / 183 |
skin | 55% | 14.78 | 993 / 1809 | 1% | 0.01 | 4 / 472 |
intestine | 49% | 12.52 | 469 / 966 | 1% | 0.02 | 7 / 527 |
muscle | 42% | 11.75 | 334 / 803 | 0% | 0 | 0 / 0 |
heart | 40% | 10.06 | 343 / 861 | 0% | 0 | 0 / 0 |
stomach | 36% | 12.64 | 128 / 359 | 2% | 0.04 | 7 / 286 |
spleen | 11% | 2.18 | 27 / 241 | 0% | 0 | 0 / 0 |
liver | 6% | 1.07 | 13 / 226 | 1% | 0.01 | 3 / 406 |
peripheral blood | 4% | 0.91 | 38 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060271 | Biological process | cilium assembly |
GO_0007618 | Biological process | mating |
GO_0007224 | Biological process | smoothened signaling pathway |
GO_0030317 | Biological process | flagellated sperm motility |
GO_0031514 | Cellular component | motile cilium |
GO_0001534 | Cellular component | radial spoke |
GO_0001669 | Cellular component | acrosomal vesicle |
GO_0036126 | Cellular component | sperm flagellum |
GO_0097729 | Cellular component | 9+2 motile cilium |
GO_0005515 | Molecular function | protein binding |
Gene name | IQUB |
Protein name | IQ motif and ubiquitin-like domain-containing protein IQ motif and ubiquitin domain containing (IQUB protein) |
Synonyms | |
Description | FUNCTION: Adapter protein that anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes . The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum . May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1 . Additionally, may play a role in the functioning of cilia (By similarity). Not required for the functioning of tracheal or ependymal cilia (By similarity). . |
Accessions | Q8NA54 ENST00000469057.1 ENST00000324698.11 [Q8NA54-1] ENST00000484508.5 [Q8NA54-2] A1A4Z1 ENST00000466202.5 [Q8NA54-1] |