Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 33 studies | 30% ± 11% | |
ciliated cell | 20 studies | 71% ± 19% | |
memory B cell | 20 studies | 28% ± 7% | |
naive B cell | 18 studies | 28% ± 6% | |
fibroblast | 17 studies | 24% ± 10% | |
type I pneumocyte | 12 studies | 49% ± 13% | |
endothelial cell | 11 studies | 22% ± 4% | |
type II pneumocyte | 10 studies | 36% ± 12% | |
epithelial cell | 8 studies | 39% ± 13% | |
endothelial cell of lymphatic vessel | 7 studies | 23% ± 7% | |
smooth muscle cell | 7 studies | 20% ± 5% | |
pericyte | 6 studies | 21% ± 4% | |
club cell | 6 studies | 35% ± 20% | |
basal cell | 6 studies | 27% ± 11% | |
myofibroblast cell | 5 studies | 19% ± 2% | |
retinal cone cell | 5 studies | 39% ± 19% | |
deuterosomal cell | 4 studies | 47% ± 6% | |
pancreatic A cell | 4 studies | 39% ± 7% | |
connective tissue cell | 4 studies | 23% ± 5% | |
astrocyte | 4 studies | 26% ± 5% | |
type B pancreatic cell | 3 studies | 35% ± 9% | |
non-classical monocyte | 3 studies | 25% ± 6% | |
kidney loop of Henle epithelial cell | 3 studies | 20% ± 4% | |
precursor B cell | 3 studies | 25% ± 1% | |
immature B cell | 3 studies | 27% ± 2% | |
retinal rod cell | 3 studies | 28% ± 9% | |
abnormal cell | 3 studies | 26% ± 3% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 17% ± 1% | |
GABAergic neuron | 3 studies | 30% ± 3% | |
glutamatergic neuron | 3 studies | 55% ± 7% | |
pancreatic ductal cell | 3 studies | 48% ± 11% | |
intestinal crypt stem cell | 3 studies | 19% ± 2% | |
goblet cell | 3 studies | 16% ± 0% | |
secretory cell | 3 studies | 27% ± 11% | |
neuron | 3 studies | 25% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 2341.88 | 180 / 180 | 100% | 58.01 | 430 / 430 |
prostate | 100% | 3963.60 | 245 / 245 | 100% | 94.33 | 502 / 502 |
lung | 100% | 4715.63 | 578 / 578 | 100% | 60.52 | 1151 / 1155 |
thymus | 100% | 3499.86 | 653 / 653 | 99% | 72.18 | 601 / 605 |
intestine | 100% | 2114.19 | 966 / 966 | 98% | 34.52 | 519 / 527 |
breast | 100% | 1951.97 | 459 / 459 | 98% | 34.34 | 1100 / 1118 |
brain | 99% | 1274.57 | 2613 / 2642 | 99% | 32.91 | 701 / 705 |
pancreas | 100% | 1413.90 | 328 / 328 | 98% | 36.98 | 175 / 178 |
uterus | 100% | 2211.95 | 170 / 170 | 98% | 38.02 | 451 / 459 |
kidney | 100% | 2163.47 | 89 / 89 | 98% | 39.19 | 881 / 901 |
stomach | 100% | 1488.50 | 359 / 359 | 97% | 32.77 | 278 / 286 |
esophagus | 100% | 1883.79 | 1443 / 1445 | 97% | 26.14 | 177 / 183 |
adrenal gland | 100% | 2283.42 | 258 / 258 | 97% | 26.98 | 222 / 230 |
bladder | 100% | 1907.52 | 21 / 21 | 96% | 33.63 | 483 / 504 |
skin | 100% | 1574.20 | 1805 / 1809 | 83% | 21.41 | 394 / 472 |
adipose | 100% | 1829.51 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 52.82 | 29 / 29 |
spleen | 100% | 1635.17 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 36.22 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.41 | 1 / 1 |
blood vessel | 100% | 2076.70 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 94% | 1060.80 | 812 / 861 | 0% | 0 | 0 / 0 |
muscle | 77% | 483.70 | 617 / 803 | 0% | 0 | 0 / 0 |
liver | 26% | 122.38 | 58 / 226 | 27% | 6.01 | 108 / 406 |
peripheral blood | 40% | 326.78 | 367 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 24% | 3.43 | 19 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1905515 | Biological process | non-motile cilium assembly |
GO_0060271 | Biological process | cilium assembly |
GO_0006919 | Biological process | activation of cysteine-type endopeptidase activity involved in apoptotic process |
GO_0007224 | Biological process | smoothened signaling pathway |
GO_0001947 | Biological process | heart looping |
GO_0044458 | Biological process | motile cilium assembly |
GO_0010839 | Biological process | negative regulation of keratinocyte proliferation |
GO_0042981 | Biological process | regulation of apoptotic process |
GO_0001843 | Biological process | neural tube closure |
GO_0006915 | Biological process | apoptotic process |
GO_0035720 | Biological process | intraciliary anterograde transport |
GO_0042073 | Biological process | intraciliary transport |
GO_0043616 | Biological process | keratinocyte proliferation |
GO_0032391 | Cellular component | photoreceptor connecting cilium |
GO_0005813 | Cellular component | centrosome |
GO_0030992 | Cellular component | intraciliary transport particle B |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0044292 | Cellular component | dendrite terminus |
GO_0005930 | Cellular component | axoneme |
GO_0097542 | Cellular component | ciliary tip |
GO_0005929 | Cellular component | cilium |
GO_0097546 | Cellular component | ciliary base |
GO_0036064 | Cellular component | ciliary basal body |
GO_0003677 | Molecular function | DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | IFT57 |
Protein name | Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2) Intraflagellar transport protein 57 homolog |
Synonyms | HIPPI DERP8 ESRRBL1 |
Description | FUNCTION: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. . |
Accessions | C9JB84 F8WBM2 ENST00000264538.4 ENST00000478157.1 ENST00000492106.1 Q9NWB7 |