heart looping

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1DLL1-NOTCH1DLL1_HUMAN - NOTC1_HUMANLigand-ReceptorSignaling by Notch
2DLL1-NOTCH2DLL1_HUMAN - NOTC2_HUMANLigand-ReceptorSignaling by Notch

II. Literature review

[source]
Nameheart looping
IDGO_0001947
collection_id

Biological process

Exact synonym

cardiac looping

Description

The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceding septation.

External URL
Genes