C2CD3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008589Biological processregulation of smoothened signaling pathway
GO_1905515Biological processnon-motile cilium assembly
GO_0060271Biological processcilium assembly
GO_0001701Biological processin utero embryonic development
GO_0001947Biological processheart looping
GO_0042733Biological processembryonic digit morphogenesis
GO_0071539Biological processprotein localization to centrosome
GO_0016485Biological processprotein processing
GO_0061511Biological processcentriole elongation
GO_0021997Biological processneural plate axis specification
GO_0007420Biological processbrain development
GO_0030162Biological processregulation of proteolysis
GO_0021915Biological processneural tube development
GO_0034451Cellular componentcentriolar satellite
GO_0005813Cellular componentcentrosome
GO_0005814Cellular componentcentriole
GO_0005829Cellular componentcytosol
GO_0036064Cellular componentciliary basal body
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameC2CD3
Protein nameC2 domain-containing protein 3
C2 domain containing 3 centriole elongation regulator
Synonyms
DescriptionFUNCTION: Component of the centrioles that acts as a positive regulator of centriole elongation . Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation . Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3. .

AccessionsQ4AC94
ENST00000680231.1
H7C288
ENST00000442398.7 [Q4AC94-4]
ENST00000680839.1
ENST00000681811.1
A0A7P0TAM9
ENST00000680645.1
ENST00000681609.1
A0A7P0Z475
H0YG44
ENST00000539061.6
ENST00000535954.2
A0A7P0Z464
F5H0U2
A0A7P0TAU6
ENST00000681310.1
A0A7P0T883
ENST00000679906.1
ENST00000681291.1
ENST00000680718.1
ENST00000681385.1
ENST00000681924.1
ENST00000679415.1
ENST00000442398
ENST00000681829.1
A0A7P0T8H7
ENST00000681345.1
A0A7P0Z4J2
H7BZB4
ENST00000681143.1
ENST00000680665.1
A0A7P0Z4H1
ENST00000414160.7
ENST00000334126.12 [Q4AC94-5]
A0A7P0T9H1
H0YFM6
A0A7P0T8V8
A0A7P0T995
A0A7P0T8E9
A0A7P0T831
ENST00000538361.2
ENST00000313663.11 [Q4AC94-1]