DNAAF1 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of DNAAF1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	93%	734.67	2466 / 2642	55%	1.60	386 / 705
kidney	98%	282.99	87 / 89	41%	1.60	368 / 901
thymus	100%	891.06	653 / 653	28%	0.82	170 / 605
lung	92%	1618.06	530 / 578	29%	1.48	334 / 1155
breast	56%	138.61	258 / 459	57%	2.02	634 / 1118
ovary	75%	130.24	135 / 180	34%	1.33	146 / 430
adrenal gland	50%	73.25	129 / 258	47%	1.44	107 / 230
spleen	67%	131.64	162 / 241	0%	0	0 / 0
prostate	56%	82.09	137 / 245	8%	0.27	41 / 502
uterus	39%	402.25	66 / 170	13%	0.70	58 / 459
pancreas	20%	22.02	64 / 328	8%	0.20	14 / 178
liver	13%	29.50	29 / 226	13%	0.39	52 / 406
intestine	14%	17.12	137 / 966	2%	0.03	9 / 527
adipose	12%	16.72	145 / 1204	0%	0	0 / 0
skin	9%	10.25	166 / 1809	2%	0.04	11 / 472
peripheral blood	11%	24.86	103 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	9%	0.14	7 / 80
esophagus	3%	3.59	41 / 1445	5%	0.14	9 / 183
lymph node	0%	0	0 / 0	7%	0.14	2 / 29
stomach	5%	6.28	18 / 359	2%	0.02	5 / 286
blood vessel	5%	6.52	62 / 1335	0%	0	0 / 0
bladder	0%	0	0 / 21	4%	0.10	18 / 504
heart	3%	4.21	30 / 861	0%	0	0 / 0
muscle	1%	1.50	7 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071910	Biological process	determination of liver left/right asymmetry
GO_0060271	Biological process	cilium assembly
GO_0030324	Biological process	lung development
GO_0001947	Biological process	heart looping
GO_0060287	Biological process	epithelial cilium movement involved in determination of left/right asymmetry
GO_0044458	Biological process	motile cilium assembly
GO_0035469	Biological process	determination of pancreatic left/right asymmetry
GO_0003356	Biological process	regulation of cilium beat frequency
GO_0071907	Biological process	determination of digestive tract left/right asymmetry
GO_0070286	Biological process	axonemal dynein complex assembly
GO_0060972	Biological process	left/right pattern formation
GO_0035082	Biological process	axoneme assembly
GO_0003341	Biological process	cilium movement
GO_0036158	Biological process	outer dynein arm assembly
GO_0036159	Biological process	inner dynein arm assembly
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0000922	Cellular component	spindle pole
GO_0016607	Cellular component	nuclear speck
GO_0005930	Cellular component	axoneme
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0070840	Molecular function	dynein complex binding

Gene name	DNAAF1
Protein name	Dynein axonemal assembly factor 1 (Leucine-rich repeat-containing protein 50) Dynein axonemal assembly factor 1
Synonyms	LRRC50
Description	FUNCTION: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. . FUNCTION: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. .
Accessions	Q8NEP3 H3BP51 ENST00000563093.5 [Q8NEP3-3] H3BV09 ENST00000378553.10 [Q8NEP3-1] ENST00000569735.1 ENST00000564928.1 ENST00000567918.5 H3BNQ4

DNAAF1 report