lung development

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1FGF1-FGFR2FGF1_HUMAN - FGFR2_HUMANLigand-ReceptorSignaling by Fibroblast growth factor
2FGF2-FGFR2FGF2_HUMAN - FGFR2_HUMANLigand-ReceptorSignaling by Fibroblast growth factor
3FGF7-FGFR2FGF7_HUMAN - FGFR2_HUMANLigand-ReceptorSignaling by Fibroblast growth factor
4RBP4-STRA6RET4_HUMAN - STRA6_HUMANLigand-Receptor

II. Literature review

[source]
Namelung development
IDGO_0030324
collection_id

Biological process

Description

The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.

External URL
Genes