Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 5 studies | 27% ± 12% |
Insufficient scRNA-seq data for expression of SLC23A1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 1393.28 | 226 / 226 | 95% | 21.70 | 387 / 406 |
| prostate | 98% | 387.39 | 241 / 245 | 97% | 13.80 | 486 / 502 |
| kidney | 100% | 1239.24 | 89 / 89 | 81% | 12.46 | 726 / 901 |
| breast | 96% | 47.63 | 439 / 459 | 37% | 1.88 | 410 / 1118 |
| ovary | 99% | 58.32 | 178 / 180 | 25% | 1.70 | 106 / 430 |
| stomach | 86% | 34.20 | 310 / 359 | 33% | 1.61 | 94 / 286 |
| intestine | 88% | 706.73 | 850 / 966 | 30% | 1.39 | 160 / 527 |
| pancreas | 99% | 75.07 | 324 / 328 | 18% | 0.87 | 32 / 178 |
| lung | 98% | 107.66 | 566 / 578 | 13% | 0.69 | 149 / 1155 |
| uterus | 96% | 119.88 | 163 / 170 | 14% | 1.16 | 64 / 459 |
| thymus | 97% | 48.65 | 635 / 653 | 11% | 0.79 | 65 / 605 |
| spleen | 100% | 166.05 | 241 / 241 | 0% | 0 | 0 / 0 |
| skin | 94% | 119.00 | 1698 / 1809 | 1% | 0.02 | 3 / 472 |
| esophagus | 79% | 27.85 | 1136 / 1445 | 10% | 1.07 | 19 / 183 |
| bladder | 71% | 26.52 | 15 / 21 | 17% | 0.97 | 87 / 504 |
| adrenal gland | 85% | 27.24 | 219 / 258 | 0% | 0.23 | 1 / 230 |
| adipose | 84% | 31.11 | 1014 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 67% | 77.42 | 619 / 929 | 0% | 0 | 0 / 0 |
| brain | 64% | 29.65 | 1678 / 2642 | 0% | 0.01 | 2 / 705 |
| blood vessel | 55% | 16.34 | 739 / 1335 | 0% | 0 | 0 / 0 |
| heart | 41% | 10.14 | 352 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 1.62 | 8 / 29 |
| muscle | 17% | 3.72 | 136 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.14 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0015882 | Biological process | L-ascorbic acid transmembrane transport |
| GO_0030324 | Biological process | lung development |
| GO_0015851 | Biological process | nucleobase transport |
| GO_0015747 | Biological process | urate transport |
| GO_0019852 | Biological process | L-ascorbic acid metabolic process |
| GO_0070837 | Biological process | dehydroascorbic acid transport |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0007420 | Biological process | brain development |
| GO_0009636 | Biological process | response to toxic substance |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043229 | Cellular component | intracellular organelle |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0009925 | Cellular component | basal plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0015205 | Molecular function | nucleobase transmembrane transporter activity |
| GO_0008520 | Molecular function | L-ascorbate:sodium symporter activity |
| GO_0015229 | Molecular function | L-ascorbic acid transmembrane transporter activity |
| GO_0015143 | Molecular function | urate transmembrane transporter activity |
| GO_0015081 | Molecular function | sodium ion transmembrane transporter activity |
| GO_0033300 | Molecular function | dehydroascorbic acid transmembrane transporter activity |
| GO_0005215 | Molecular function | transporter activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SLC23A1 |
| Protein name | Solute carrier family 23 member 1 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) |
| Synonyms | SVCT1 YSPL3 |
| Description | FUNCTION: Sodium:ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate . Has retained some ancestral activity toward nucleobases such as urate, an oxidized purine. Low-affinity high-capacity sodium:urate cotransporter, may regulate serum urate levels by serving as a renal urate re-absorber . .; FUNCTION: [Isoform 2]: Inactive transporter. . |
| Accessions | ENST00000348729.8 [Q9UHI7-1] H0Y902 ENST00000504513.1 H0YAJ1 ENST00000353963.7 [Q9UHI7-2] Q9UHI7 ENST00000508270.1 |