SLC23A1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC23A1 at tissue level.

III. Associated gene sets

GO_0015882Biological processL-ascorbic acid transmembrane transport
GO_0030324Biological processlung development
GO_0015851Biological processnucleobase transport
GO_0015747Biological processurate transport
GO_0019852Biological processL-ascorbic acid metabolic process
GO_0070837Biological processdehydroascorbic acid transport
GO_0006814Biological processsodium ion transport
GO_0007420Biological processbrain development
GO_0009636Biological processresponse to toxic substance
GO_0035725Biological processsodium ion transmembrane transport
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0043229Cellular componentintracellular organelle
GO_0070062Cellular componentextracellular exosome
GO_0009925Cellular componentbasal plasma membrane
GO_0005737Cellular componentcytoplasm
GO_0015205Molecular functionnucleobase transmembrane transporter activity
GO_0008520Molecular functionL-ascorbate:sodium symporter activity
GO_0015229Molecular functionL-ascorbic acid transmembrane transporter activity
GO_0015143Molecular functionurate transmembrane transporter activity
GO_0015081Molecular functionsodium ion transmembrane transporter activity
GO_0033300Molecular functiondehydroascorbic acid transmembrane transporter activity
GO_0005215Molecular functiontransporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC23A1
Protein nameSolute carrier family 23 member 1
Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3)
SynonymsSVCT1
YSPL3
DescriptionFUNCTION: Sodium:ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate . Has retained some ancestral activity toward nucleobases such as urate, an oxidized purine. Low-affinity high-capacity sodium:urate cotransporter, may regulate serum urate levels by serving as a renal urate re-absorber . .; FUNCTION: [Isoform 2]: Inactive transporter. .

AccessionsENST00000348729.8 [Q9UHI7-1]
H0Y902
ENST00000504513.1
H0YAJ1
ENST00000353963.7 [Q9UHI7-2]
Q9UHI7
ENST00000508270.1