Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 34 studies | 37% ± 14% | |
| connective tissue cell | 10 studies | 32% ± 12% | |
| pericyte | 7 studies | 20% ± 6% | |
| smooth muscle cell | 7 studies | 42% ± 15% | |
| myofibroblast cell | 5 studies | 31% ± 4% | |
| adventitial cell | 5 studies | 47% ± 5% | |
| renal alpha-intercalated cell | 3 studies | 22% ± 3% |
Insufficient scRNA-seq data for expression of FGF7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 4887.05 | 568 / 578 | 89% | 6.33 | 1026 / 1155 |
| breast | 98% | 4099.50 | 449 / 459 | 88% | 5.61 | 985 / 1118 |
| prostate | 84% | 2584.62 | 207 / 245 | 86% | 4.61 | 434 / 502 |
| bladder | 100% | 5903.24 | 21 / 21 | 65% | 4.26 | 327 / 504 |
| esophagus | 79% | 2606.16 | 1140 / 1445 | 72% | 4.82 | 132 / 183 |
| intestine | 81% | 2536.07 | 783 / 966 | 67% | 4.18 | 353 / 527 |
| thymus | 99% | 3420.61 | 646 / 653 | 47% | 2.43 | 284 / 605 |
| uterus | 99% | 5464.17 | 169 / 170 | 46% | 5.55 | 213 / 459 |
| ovary | 97% | 2881.61 | 175 / 180 | 42% | 1.79 | 180 / 430 |
| stomach | 51% | 1477.33 | 182 / 359 | 77% | 7.44 | 219 / 286 |
| skin | 68% | 3030.79 | 1227 / 1809 | 59% | 2.44 | 280 / 472 |
| pancreas | 14% | 161.41 | 46 / 328 | 88% | 8.17 | 156 / 178 |
| adipose | 100% | 6052.13 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 85% | 2906.74 | 1140 / 1335 | 0% | 0 | 0 / 0 |
| heart | 79% | 1405.67 | 678 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 2.35 | 21 / 29 |
| kidney | 37% | 834.40 | 33 / 89 | 35% | 3.02 | 316 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 42% | 0.93 | 19 / 45 |
| adrenal gland | 15% | 171.56 | 38 / 258 | 19% | 2.60 | 43 / 230 |
| liver | 1% | 14.65 | 3 / 226 | 19% | 0.50 | 76 / 406 |
| muscle | 15% | 243.76 | 118 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 1.54 | 3 / 2642 | 2% | 0.18 | 15 / 705 |
| spleen | 1% | 7.30 | 2 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060665 | Biological process | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling |
| GO_0051781 | Biological process | positive regulation of cell division |
| GO_0030324 | Biological process | lung development |
| GO_0008544 | Biological process | epidermis development |
| GO_0060501 | Biological process | positive regulation of epithelial cell proliferation involved in lung morphogenesis |
| GO_0060445 | Biological process | branching involved in salivary gland morphogenesis |
| GO_0050918 | Biological process | positive chemotaxis |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0007165 | Biological process | signal transduction |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0031069 | Biological process | hair follicle morphogenesis |
| GO_0061033 | Biological process | secretion by lung epithelial cell involved in lung growth |
| GO_0010838 | Biological process | positive regulation of keratinocyte proliferation |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0034394 | Biological process | protein localization to cell surface |
| GO_2000288 | Biological process | positive regulation of myoblast proliferation |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_0050679 | Biological process | positive regulation of epithelial cell proliferation |
| GO_0050731 | Biological process | positive regulation of peptidyl-tyrosine phosphorylation |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0001938 | Biological process | positive regulation of endothelial cell proliferation |
| GO_0051450 | Biological process | myoblast proliferation |
| GO_0030154 | Biological process | cell differentiation |
| GO_0030334 | Biological process | regulation of cell migration |
| GO_0051549 | Biological process | positive regulation of keratinocyte migration |
| GO_0001935 | Biological process | endothelial cell proliferation |
| GO_0010463 | Biological process | mesenchymal cell proliferation |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0009611 | Biological process | response to wounding |
| GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0008201 | Molecular function | heparin binding |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0042056 | Molecular function | chemoattractant activity |
| GO_0005111 | Molecular function | type 2 fibroblast growth factor receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | FGF7 |
| Protein name | Fibroblast growth factor (FGF) Fibroblast growth factor 7 (FGF-7) (Heparin-binding growth factor 7) (HBGF-7) (Keratinocyte growth factor) |
| Synonyms | KGF |
| Description | FUNCTION: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. . |
| Accessions | P21781 H0YNE7 ENST00000267843.9 [P21781-1] Q6RK68 ENST00000560270.1 [P21781-2] ENST00000560979.1 |
