GO_0043410 | OmnibusX

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	EFNA1-EPHA8	EFNA1_HUMAN - EPHA8_HUMAN	Ligand-Receptor	Signaling by Ephrin
2	FGF10-FGFR2	FGF10_HUMAN - FGFR2_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
3	FGF17-FGFR3	FGF17_HUMAN - FGFR3_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
4	FGF2-FGFR1	FGF2_HUMAN - FGFR1_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
5	FGF2-FGFR2	FGF2_HUMAN - FGFR2_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
6	FGF2-FGFR3	FGF2_HUMAN - FGFR3_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
7	FGF20-FGFR3	FGF20_HUMAN - FGFR3_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
8	FGF22-FGFR2	FGF22_HUMAN - FGFR2_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
9	FGF23-FGFR1+KL	FGF23_HUMAN -	Ligand-Receptor	Signaling by Fibroblast growth factor
10	FGF3-FGFR2	FGF3_HUMAN - FGFR2_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
11	FGF4-FGFR1	FGF4_HUMAN - FGFR1_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
12	FGF5-FGFR1	FGF5_HUMAN - FGFR1_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
13	FGF6-FGFR1	FGF6_HUMAN - FGFR1_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
14	FGF7-FGFR2	FGF7_HUMAN - FGFR2_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
15	FGF8-FGFR3	FGF8_HUMAN - FGFR3_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
16	FGF9-FGFR3	FGF9_HUMAN - FGFR3_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
17	IGF1-GPC3+IGF1R	IGF1_HUMAN -	Ligand-Receptor	Signaling by Insulin-like growth factor
18	IGF1-IGF1R	IGF1_HUMAN - IGF1R_HUMAN	Ligand-Receptor	Signaling by Insulin-like growth factor
19	IGF2-IGF1R	IGF2_HUMAN - IGF1R_HUMAN	Ligand-Receptor	Signaling by Insulin-like growth factor
20	INS-INSR	INS_HUMAN - INSR_HUMAN	Ligand-Receptor	Signaling by Insulin-like precursor
21	VEGFA-FLT1	VEGFA_HUMAN - VGFR1_HUMAN	Ligand-Receptor	Signaling by Vascular endothelial growth factor
22	VEGFA-FLT1+KDR	VEGFA_HUMAN -	Ligand-Receptor	Signaling by Vascular endothelial growth factor
23	VEGFA-KDR	VEGFA_HUMAN - VGFR2_HUMAN	Ligand-Receptor	Signaling by Vascular endothelial growth factor
24	WNT4-FZD7+LRP5	WNT4_HUMAN -	Ligand-Receptor	Signaling by WNT
25	WNT4-FZD7+LRP6	WNT4_HUMAN -	Ligand-Receptor	Signaling by WNT
26	WNT5A-FZD7+LRP5	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
27	WNT5A-FZD7+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
28	WNT5A-FZD8+RYK	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT

II. Literature review

[source]

Name	positive regulation of MAPK cascade
ID	GO_0043410
collection_id	Biological process
Exact synonym	positive regulation of MAP kinase cascade, positive regulation of MAP kinase kinase kinase cascade, positive regulation of MAPKKK cascade, positive regulation of mitogen activated protein kinase kinase kinase cascade, positive regulation of mitogen-activated protein kinase cascade, positive regulation of mitogen-activated protein kinase kinase kinase cascade, stimulation of MAPK cascade, up regulation of MAPKKK cascade, up-regulation of MAPK cascade, up-regulation of MAPKKK cascade, upregulation of MAPK cascade, upregulation of MAPKKK cascade
Description	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
External URL
Genes	DRD3 NENF ADAM8 THPO KIT LAMTOR1 KSR2 PDE6H FGF6 ERBB2 INAVA PDGFA KSR1 GSDME ADRA2A OSM NDST1 FGF18 SPAG9 HLA-DRB1 INS PROK1 PRKCE MADD PPIA FGF22 DUSP19 FRS2 CAV2 GRM5 RET FGF21 ROCK1 LAMTOR3 SOD1 IL11 FGF9 CX3CL1 CDK10 FCRL3 PRDX2 WWC1 EFNA1 PDE6G FGFR1 PDGFB IQGAP3 NTRK2 il15-il15r_human FGF2 LIF GPR37L1 SYK AR LPAR1 TGFB3 LEP IGF2 ROCK2 PHB2 CD4 RYK TBX1 TGFA EPHA8 NKD1 FGF16 HGF TAB1 ALOX12B TGFB1 CSPG4 abeta-42-oligomer_human ADRB2 BMP2 URS00001F1DA8_9606 FGF4 KISS1 DAB2IP FGF3 GHRL PTPRC EGF DOK5 KDR FGF20 F2R INSR HMGB1 MAP4K1 DOK4 IGFBP3 il-27r_human ADRA2C GRM1 NOD2 LAPTM5 DOK1 WNT4 EIF2AK2 FLT4 GPER1 TRIM5 FLT1 GRM4 FGF19 NMNAT1 GPR37 MAP2K3 DRD1 WNT5A SORBS3 LYN PLCG2 RAF1 FLT3 MEF2C TRAF7 LPAR3 IAPP CDH2 VEGFA IGF1R FGF8 C1QTNF1 CD74 CHRNA7 ADRA1A LPAR2 FZD7 PTPRJ RIT2 ADRA1D TAOK2 DOK2 CRIPTO FGF7 DHX33 TLR9 MYDGF IGF1 IQGAP1 MAP2K6 FGF23 DOK3 JAK2 FGFR3 TMEM106A ADORA1 TP73 GPR101 P2RX7 ADRB3 DRD2 BCAR3 SOX2 FGF17 AVPI1 ADRB1 DRD5 TNF CD81 DOK6 ZNF622 FGF5 IL6 FGF10 EPGN CTNNB1 SHC1 IGFBP6 BANK1 ADRA1B AVPR1B GDF15 ITGA1 LILRA5 LAMTOR2 HRAS GFRAL JCAD MOS IGFBP4 TEK FGFR2 CARTPT PELI2 CDON ADRA2B

positive regulation of MAPK cascade

I. Involved cell-cell interactions

II. Literature review