AVPR1B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AVPR1B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AVPR1B at tissue level.

III. Associated gene sets

GO_0032430Biological processpositive regulation of phospholipase A2 activity
GO_0046718Biological processsymbiont entry into host cell
GO_0045907Biological processpositive regulation of vasoconstriction
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0090238Biological processpositive regulation of arachidonic acid secretion
GO_0032870Biological processcellular response to hormone stimulus
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0060732Biological processpositive regulation of inositol phosphate biosynthetic process
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0042127Biological processregulation of cell population proliferation
GO_0001992Biological processregulation of systemic arterial blood pressure by vasopressin
GO_0150104Biological processtransport across blood-brain barrier
GO_0005768Cellular componentendosome
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0042277Molecular functionpeptide binding
GO_0005080Molecular functionprotein kinase C binding
GO_0005000Molecular functionvasopressin receptor activity

IV. Literature review

[source]
Gene nameAVPR1B
Protein nameVasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor)
SynonymsAVPR3
VPR3
DescriptionFUNCTION: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.; FUNCTION: (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, may recognize and internalize the complex formed by AVP/Arg-vasopressin, SARS-CoV-2 spike protein and secreted ACE2 through DNM2/dynamin 2-dependent endocytosis. .

AccessionsENST00000367126.5
P47901