Insufficient scRNA-seq data for expression of AVPR1B at single-cell level.
Insufficient scRNA-seq data for expression of AVPR1B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 82% | 11.62 | 73 / 89 | 67% | 5.12 | 601 / 901 |
| pancreas | 75% | 8.76 | 245 / 328 | 25% | 1.14 | 44 / 178 |
| intestine | 79% | 8.33 | 762 / 966 | 2% | 0.07 | 9 / 527 |
| thymus | 64% | 5.21 | 415 / 653 | 12% | 0.17 | 71 / 605 |
| stomach | 72% | 30.21 | 260 / 359 | 1% | 0.01 | 2 / 286 |
| uterus | 31% | 3.22 | 53 / 170 | 5% | 0.14 | 24 / 459 |
| brain | 36% | 7.47 | 944 / 2642 | 0% | 0.01 | 3 / 705 |
| bladder | 33% | 3.00 | 7 / 21 | 1% | 0.04 | 6 / 504 |
| ovary | 6% | 0.28 | 11 / 180 | 24% | 0.64 | 105 / 430 |
| spleen | 26% | 1.25 | 63 / 241 | 0% | 0 | 0 / 0 |
| prostate | 22% | 1.24 | 53 / 245 | 3% | 0.15 | 17 / 502 |
| lung | 17% | 0.83 | 100 / 578 | 2% | 0.07 | 25 / 1155 |
| skin | 16% | 0.98 | 296 / 1809 | 0% | 0.01 | 1 / 472 |
| esophagus | 10% | 0.53 | 138 / 1445 | 2% | 0.13 | 3 / 183 |
| peripheral blood | 10% | 0.49 | 94 / 929 | 0% | 0 | 0 / 0 |
| adipose | 9% | 0.50 | 108 / 1204 | 0% | 0 | 0 / 0 |
| heart | 8% | 0.36 | 73 / 861 | 0% | 0 | 0 / 0 |
| breast | 8% | 0.30 | 36 / 459 | 0% | 0.01 | 4 / 1118 |
| adrenal gland | 5% | 0.23 | 12 / 258 | 0% | 0.02 | 1 / 230 |
| liver | 4% | 0.16 | 8 / 226 | 1% | 0.04 | 5 / 406 |
| blood vessel | 4% | 0.24 | 56 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 3% | 0.10 | 21 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032430 | Biological process | positive regulation of phospholipase A2 activity |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0045907 | Biological process | positive regulation of vasoconstriction |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0090238 | Biological process | positive regulation of arachidonic acid secretion |
| GO_0032870 | Biological process | cellular response to hormone stimulus |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0060732 | Biological process | positive regulation of inositol phosphate biosynthetic process |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_0001992 | Biological process | regulation of systemic arterial blood pressure by vasopressin |
| GO_0150104 | Biological process | transport across blood-brain barrier |
| GO_0005768 | Cellular component | endosome |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0042277 | Molecular function | peptide binding |
| GO_0005080 | Molecular function | protein kinase C binding |
| GO_0005000 | Molecular function | vasopressin receptor activity |
| Gene name | AVPR1B |
| Protein name | Vasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor) |
| Synonyms | AVPR3 VPR3 |
| Description | FUNCTION: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.; FUNCTION: (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, may recognize and internalize the complex formed by AVP/Arg-vasopressin, SARS-CoV-2 spike protein and secreted ACE2 through DNM2/dynamin 2-dependent endocytosis. . |
| Accessions | ENST00000367126.5 P47901 |