IAPP | OmnibusX

Name	Number of supported studies	Average coverage
type B pancreatic cell	4 studies	75% ± 14%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of IAPP at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	98%	2472.05	320 / 328	63%	55.83	113 / 178
liver	81%	44.73	182 / 226	4%	0.69	17 / 406
prostate	0%	0	0 / 245	9%	0.81	47 / 502
kidney	3%	0.46	3 / 89	0%	0.00	2 / 901
thymus	2%	0.44	14 / 653	1%	0.02	6 / 605
brain	3%	0.73	77 / 2642	0%	0.00	1 / 705
intestine	1%	0.12	6 / 966	2%	1.94	12 / 527
esophagus	1%	0.10	11 / 1445	2%	0.02	3 / 183
adrenal gland	0%	0	0 / 258	2%	0.05	4 / 230
stomach	1%	0.09	2 / 359	1%	0.03	3 / 286
lung	0%	0.06	1 / 578	1%	0.03	16 / 1155
breast	1%	0.43	4 / 459	1%	0.57	7 / 1118
skin	1%	0.23	18 / 1809	0%	0.01	2 / 472
ovary	0%	0	0 / 180	1%	0.02	5 / 430
adipose	1%	0.59	13 / 1204	0%	0	0 / 0
heart	1%	0.12	7 / 861	0%	0	0 / 0
uterus	0%	0	0 / 170	0%	0.01	2 / 459
spleen	0%	0.11	1 / 241	0%	0	0 / 0
muscle	0%	0.02	2 / 803	0%	0	0 / 0
blood vessel	0%	0.09	3 / 1335	0%	0	0 / 0
bladder	0%	0	0 / 21	0%	0.00	1 / 504
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0019233	Biological process	sensory perception of pain
GO_0050850	Biological process	positive regulation of calcium-mediated signaling
GO_0030316	Biological process	osteoclast differentiation
GO_0045779	Biological process	negative regulation of bone resorption
GO_0007165	Biological process	signal transduction
GO_0031333	Biological process	negative regulation of protein-containing complex assembly
GO_0043410	Biological process	positive regulation of MAPK cascade
GO_0007267	Biological process	cell-cell signaling
GO_0097647	Biological process	amylin receptor signaling pathway
GO_0010739	Biological process	positive regulation of protein kinase A signaling
GO_1905907	Biological process	negative regulation of amyloid fibril formation
GO_0042755	Biological process	eating behavior
GO_0045453	Biological process	bone resorption
GO_0006915	Biological process	apoptotic process
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0045671	Biological process	negative regulation of osteoclast differentiation
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0008289	Molecular function	lipid binding
GO_0048018	Molecular function	receptor ligand activity
GO_0001540	Molecular function	amyloid-beta binding
GO_0005179	Molecular function	hormone activity
GO_0042802	Molecular function	identical protein binding
GO_0005102	Molecular function	signaling receptor binding
GO_0005515	Molecular function	protein binding

Gene name	IAPP
Protein name	Islet amyloid polypeptide (Amylin) (Diabetes-associated peptide) (DAP) (Insulinoma amyloid peptide) Islet amyloid polypeptide Islet amyloid polypeptide (Amylin)
Synonyms
Description	FUNCTION: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. FUNCTION: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. . FUNCTION: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. .
Accessions	ENST00000535428.1 ENST00000240652.8 F5H0S1 P10997 H0YF85 ENST00000537593.1 ENST00000542023.1 ENST00000539393.5 F5H1F0

IAPP report