Biological process

down regulation of amyloid fibril formation, down-regulation of amyloid fibril formation, downregulation of amyloid fibril formation

Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation.

down regulation of amyloid fibril assembly, down regulation of amyloid structure assembly, down regulation of amyloid structure formation, down-regulation of amyloid fibril assembly, down-regulation of amyloid structure assembly, down-regulation of amyloid structure formation, downregulation of amyloid fibril assembly, downregulation of amyloid structure assembly, downregulation of amyloid structure formation, inhibition of amyloid fibril assembly, inhibition of amyloid structure assembly, inhibition of amyloid structure formation, negative regulation of amyloid fibril assembly, negative regulation of amyloid structure assembly, negative regulation of amyloid structure formation

Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896).