PFDN1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	27 studies	26% ± 11%	Explore
fibroblast	15 studies	24% ± 9%	Explore
natural killer cell	12 studies	20% ± 5%	Explore
smooth muscle cell	12 studies	21% ± 3%	Explore
capillary endothelial cell	11 studies	23% ± 6%	Explore
macrophage	11 studies	25% ± 7%	Explore
pericyte	11 studies	22% ± 6%	Explore
endothelial cell of lymphatic vessel	10 studies	26% ± 8%	Explore
non-classical monocyte	9 studies	26% ± 12%	Explore
epithelial cell	9 studies	35% ± 19%	Explore
endothelial cell of artery	8 studies	21% ± 4%	Explore
regulatory T cell	8 studies	19% ± 4%	Explore
endothelial cell of vascular tree	8 studies	21% ± 4%	Explore
type I pneumocyte	8 studies	29% ± 5%	Explore
B cell	7 studies	25% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	20% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	20% ± 4%	Explore
myofibroblast cell	7 studies	23% ± 5%	Explore
connective tissue cell	7 studies	25% ± 7%	Explore
monocyte	7 studies	19% ± 5%	Explore
vein endothelial cell	7 studies	22% ± 6%	Explore
astrocyte	7 studies	28% ± 9%	Explore
naive B cell	6 studies	19% ± 2%	Explore
CD4-positive, alpha-beta T cell	6 studies	23% ± 7%	Explore
neuron	6 studies	30% ± 13%	Explore
basal cell	6 studies	28% ± 16%	Explore
adipocyte	6 studies	23% ± 8%	Explore
classical monocyte	5 studies	25% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
CD8-positive, alpha-beta T cell	5 studies	25% ± 6%	Explore
T cell	5 studies	20% ± 3%	Explore
abnormal cell	5 studies	27% ± 8%	Explore
myeloid cell	5 studies	24% ± 10%	Explore
mesothelial cell	5 studies	26% ± 12%	Explore
oligodendrocyte	5 studies	24% ± 5%	Explore
plasmacytoid dendritic cell	5 studies	22% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	18% ± 1%	Explore
leukocyte	4 studies	21% ± 5%	Explore
conventional dendritic cell	4 studies	35% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	24% ± 5%	Explore
ciliated cell	4 studies	35% ± 12%	Explore
T follicular helper cell	4 studies	16% ± 1%	Explore
GABAergic neuron	4 studies	34% ± 10%	Explore
glutamatergic neuron	4 studies	45% ± 15%	Explore
oligodendrocyte precursor cell	4 studies	23% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	21% ± 8%	Explore
memory B cell	4 studies	19% ± 2%	Explore
gamma-delta T cell	4 studies	28% ± 19%	Explore
pancreatic A cell	3 studies	27% ± 4%	Explore
exhausted T cell	3 studies	23% ± 9%	Explore
hematopoietic precursor cell	3 studies	28% ± 12%	Explore
kidney loop of Henle epithelial cell	3 studies	20% ± 4%	Explore
progenitor cell	3 studies	23% ± 4%	Explore
epithelial cell of proximal tubule	3 studies	18% ± 4%	Explore
neural crest cell	3 studies	21% ± 2%	Explore
retinal ganglion cell	3 studies	55% ± 26%	Explore
type II pneumocyte	3 studies	28% ± 11%	Explore
Mueller cell	3 studies	19% ± 4%	Explore
muscle cell	3 studies	27% ± 9%	Explore
microglial cell	3 studies	19% ± 2%	Explore
dendritic cell	3 studies	42% ± 18%	Explore
pancreatic ductal cell	3 studies	38% ± 14%	Explore
enteroendocrine cell	3 studies	28% ± 11%	Explore
goblet cell	3 studies	20% ± 6%	Explore
interneuron	3 studies	31% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	21% ± 3%	Explore
double negative thymocyte	3 studies	30% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	22% ± 7%	Explore
lung	9 studies	26% ± 10%	Explore
brain	6 studies	32% ± 11%	Explore
intestine	5 studies	23% ± 10%	Explore
pancreas	3 studies	28% ± 6%	Explore
kidney	3 studies	18% ± 3%	Explore
eye	3 studies	26% ± 9%	Explore
liver	3 studies	30% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2565.33	258 / 258	100%	79.06	230 / 230
brain	100%	3277.08	2642 / 2642	100%	96.81	705 / 705
esophagus	100%	2676.78	1445 / 1445	100%	50.69	183 / 183
intestine	100%	2611.60	966 / 966	100%	68.85	527 / 527
kidney	100%	2579.70	89 / 89	100%	86.70	901 / 901
ovary	100%	1846.24	180 / 180	100%	78.68	430 / 430
prostate	100%	2419.12	245 / 245	100%	79.05	502 / 502
skin	100%	2738.29	1809 / 1809	100%	77.63	472 / 472
stomach	100%	1762.52	359 / 359	100%	60.55	286 / 286
thymus	100%	2463.33	653 / 653	100%	97.30	605 / 605
uterus	100%	2644.70	170 / 170	100%	84.93	459 / 459
lung	100%	2621.94	578 / 578	100%	65.08	1154 / 1155
breast	100%	2759.54	459 / 459	100%	81.48	1116 / 1118
bladder	100%	2505.38	21 / 21	100%	70.38	502 / 504
pancreas	98%	983.05	322 / 328	100%	70.16	178 / 178
liver	99%	814.86	223 / 226	99%	35.99	403 / 406
adipose	100%	2864.30	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	60.00	80 / 80
lymph node	0%	0	0 / 0	100%	91.63	29 / 29
spleen	100%	1964.14	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	79.20	45 / 45
ureter	0%	0	0 / 0	100%	30.58	1 / 1
blood vessel	100%	2790.11	1334 / 1335	0%	0	0 / 0
muscle	100%	2719.82	802 / 803	0%	0	0 / 0
heart	100%	2744.11	857 / 861	0%	0	0 / 0
peripheral blood	91%	1425.24	847 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006457	Biological process	protein folding
GO_0061077	Biological process	chaperone-mediated protein folding
GO_1905907	Biological process	negative regulation of amyloid fibril formation
GO_0016272	Cellular component	prefoldin complex
GO_0005737	Cellular component	cytoplasm
GO_0044183	Molecular function	protein folding chaperone
GO_0051082	Molecular function	unfolded protein binding
GO_0001540	Molecular function	amyloid-beta binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PFDN1
Protein name	Prefoldin subunit 1
Synonyms	PFD1
Description	FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. .
Accessions	ENST00000524074.1 ENST00000261813.9 ENST00000510217.1 O60925 E5RGS4 D6RGG5

PFDN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review