Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 1631.36 | 258 / 258 | 100% | 40.70 | 230 / 230 |
| ovary | 100% | 1045.00 | 180 / 180 | 100% | 42.51 | 430 / 430 |
| thymus | 100% | 1195.65 | 653 / 653 | 100% | 44.41 | 605 / 605 |
| skin | 100% | 1274.21 | 1808 / 1809 | 100% | 58.75 | 472 / 472 |
| brain | 100% | 1693.46 | 2640 / 2642 | 100% | 41.69 | 705 / 705 |
| uterus | 100% | 1232.04 | 170 / 170 | 100% | 59.72 | 458 / 459 |
| intestine | 100% | 1189.51 | 966 / 966 | 100% | 40.88 | 525 / 527 |
| liver | 100% | 1103.39 | 225 / 226 | 100% | 54.23 | 406 / 406 |
| prostate | 100% | 1240.84 | 245 / 245 | 99% | 41.26 | 498 / 502 |
| kidney | 100% | 1315.74 | 89 / 89 | 99% | 29.94 | 893 / 901 |
| breast | 100% | 1072.12 | 459 / 459 | 99% | 43.99 | 1108 / 1118 |
| bladder | 100% | 1259.24 | 21 / 21 | 99% | 51.23 | 498 / 504 |
| lung | 100% | 1019.72 | 576 / 578 | 99% | 38.60 | 1143 / 1155 |
| pancreas | 100% | 668.34 | 327 / 328 | 99% | 33.92 | 176 / 178 |
| stomach | 100% | 1023.94 | 359 / 359 | 98% | 33.90 | 281 / 286 |
| esophagus | 100% | 1289.09 | 1445 / 1445 | 96% | 19.03 | 175 / 183 |
| eye | 0% | 0 | 0 / 0 | 100% | 52.81 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 95.85 | 29 / 29 |
| muscle | 100% | 1548.59 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1249.90 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 39.95 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 87.18 | 1 / 1 |
| adipose | 100% | 980.18 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1015.44 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1001.81 | 846 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 86% | 1006.33 | 798 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006457 | Biological process | protein folding |
| GO_0050821 | Biological process | protein stabilization |
| GO_0061077 | Biological process | chaperone-mediated protein folding |
| GO_1905907 | Biological process | negative regulation of amyloid fibril formation |
| GO_0051131 | Biological process | chaperone-mediated protein complex assembly |
| GO_0101031 | Cellular component | protein folding chaperone complex |
| GO_0016272 | Cellular component | prefoldin complex |
| GO_1990062 | Cellular component | RPAP3/R2TP/prefoldin-like complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0051082 | Molecular function | unfolded protein binding |
| GO_0051087 | Molecular function | protein-folding chaperone binding |
| GO_0001540 | Molecular function | amyloid-beta binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PFDN6 |
| Protein name | Prefoldin subunit 6 (Protein Ke2) Prefoldin subunit 6 Prefoldin subunit 6, isoform CRA_b (cDNA, FLJ92435, Homo sapiens HLA class II region expressed gene KE2 (HKE2), mRNA) HLA class II region expressed gene KE2 (Prefoldin subunit 6, isoform CRA_a) |
| Synonyms | hCG_17527 PFD6 HKE2 |
| Description | FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. . FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. . FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. . FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. . |
| Accessions | I7HJT1 ENST00000399385.5 ENST00000468094.5 ENST00000374607.5 ENST00000463584.1 ENST00000552711.2 ENST00000448594.5 ENST00000412289.5 ENST00000491095.5 O15212 ENST00000432391.6 ENST00000548040.2 ENST00000374606.10 ENST00000474406.5 Q5STK2 ENST00000482292.5 A2AB88 ENST00000383207.6 ENST00000445559.5 ENST00000442285.5 ENST00000547952.2 ENST00000547641.2 ENST00000374610.6 ENST00000431830.5 ENST00000425878.6 ENST00000399383.7 ENST00000452658.6 ENST00000451970.5 ENST00000395131.5 |
