Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 33 studies | 35% ± 19% | |
smooth muscle cell | 28 studies | 56% ± 22% | |
pericyte | 28 studies | 42% ± 22% | |
astrocyte | 17 studies | 42% ± 28% | |
oligodendrocyte | 15 studies | 52% ± 19% | |
connective tissue cell | 11 studies | 37% ± 16% | |
endothelial cell | 10 studies | 26% ± 12% | |
myofibroblast cell | 10 studies | 47% ± 14% | |
basal cell | 10 studies | 35% ± 20% | |
mesothelial cell | 7 studies | 37% ± 12% | |
cardiac muscle cell | 7 studies | 52% ± 19% | |
epithelial cell | 7 studies | 50% ± 33% | |
epithelial cell of proximal tubule | 6 studies | 68% ± 20% | |
glial cell | 6 studies | 62% ± 27% | |
kidney loop of Henle epithelial cell | 5 studies | 42% ± 12% | |
type I pneumocyte | 5 studies | 25% ± 9% | |
parietal epithelial cell | 4 studies | 61% ± 28% | |
retinal ganglion cell | 4 studies | 50% ± 25% | |
Schwann cell | 4 studies | 63% ± 24% | |
retinal pigment epithelial cell | 4 studies | 74% ± 15% | |
adventitial cell | 4 studies | 44% ± 6% | |
Mueller cell | 4 studies | 83% ± 11% | |
secretory cell | 4 studies | 30% ± 10% | |
melanocyte | 4 studies | 59% ± 16% | |
glomerular endothelial cell | 3 studies | 30% ± 10% | |
podocyte | 3 studies | 34% ± 16% | |
OFF-bipolar cell | 3 studies | 27% ± 12% | |
ON-bipolar cell | 3 studies | 28% ± 13% | |
microglial cell | 3 studies | 44% ± 36% | |
abnormal cell | 3 studies | 75% ± 26% | |
macrophage | 3 studies | 28% ± 14% | |
renal principal cell | 3 studies | 59% ± 9% | |
adipocyte | 3 studies | 35% ± 8% | |
myoepithelial cell | 3 studies | 72% ± 15% | |
luminal cell of prostate epithelium | 3 studies | 50% ± 2% | |
muscle cell | 3 studies | 51% ± 20% | |
progenitor cell of mammary luminal epithelium | 3 studies | 56% ± 23% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 98% | 59230.96 | 87 / 89 | 93% | 1145.65 | 842 / 901 |
brain | 88% | 30295.31 | 2336 / 2642 | 99% | 1704.23 | 696 / 705 |
thymus | 83% | 16777.18 | 541 / 653 | 54% | 94.38 | 325 / 605 |
muscle | 100% | 128200.90 | 803 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 43982.94 | 1320 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 181925.97 | 842 / 861 | 0% | 0 | 0 / 0 |
skin | 37% | 5026.24 | 674 / 1809 | 60% | 187.32 | 283 / 472 |
eye | 0% | 0 | 0 / 0 | 95% | 234.94 | 76 / 80 |
breast | 77% | 18897.71 | 353 / 459 | 16% | 45.64 | 179 / 1118 |
adipose | 88% | 30019.01 | 1065 / 1204 | 0% | 0 | 0 / 0 |
uterus | 54% | 7728.88 | 92 / 170 | 17% | 37.47 | 76 / 459 |
bladder | 67% | 15773.33 | 14 / 21 | 3% | 4.25 | 15 / 504 |
esophagus | 63% | 13349.94 | 909 / 1445 | 7% | 7.62 | 12 / 183 |
intestine | 60% | 13819.86 | 582 / 966 | 1% | 1.02 | 4 / 527 |
prostate | 45% | 8787.93 | 110 / 245 | 8% | 14.39 | 41 / 502 |
ovary | 9% | 1724.36 | 17 / 180 | 27% | 48.80 | 114 / 430 |
lung | 28% | 5380.32 | 163 / 578 | 7% | 14.90 | 85 / 1155 |
stomach | 32% | 6663.83 | 114 / 359 | 2% | 3.87 | 7 / 286 |
adrenal gland | 5% | 826.76 | 13 / 258 | 5% | 5.62 | 11 / 230 |
tonsil | 0% | 0 | 0 / 0 | 9% | 12.11 | 4 / 45 |
liver | 1% | 89.23 | 2 / 226 | 6% | 20.77 | 25 / 406 |
pancreas | 1% | 58.59 | 2 / 328 | 2% | 3.61 | 4 / 178 |
spleen | 2% | 243.61 | 6 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 107.85 | 8 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042542 | Biological process | response to hydrogen peroxide |
GO_0032355 | Biological process | response to estradiol |
GO_0009408 | Biological process | response to heat |
GO_0031109 | Biological process | microtubule polymerization or depolymerization |
GO_0010629 | Biological process | negative regulation of gene expression |
GO_0031333 | Biological process | negative regulation of protein-containing complex assembly |
GO_0043067 | Biological process | regulation of programmed cell death |
GO_0007021 | Biological process | tubulin complex assembly |
GO_0006936 | Biological process | muscle contraction |
GO_2000378 | Biological process | negative regulation of reactive oxygen species metabolic process |
GO_0071480 | Biological process | cellular response to gamma radiation |
GO_0051403 | Biological process | stress-activated MAPK cascade |
GO_0006457 | Biological process | protein folding |
GO_0032387 | Biological process | negative regulation of intracellular transport |
GO_0060561 | Biological process | apoptotic process involved in morphogenesis |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0050821 | Biological process | protein stabilization |
GO_0001666 | Biological process | response to hypoxia |
GO_1905907 | Biological process | negative regulation of amyloid fibril formation |
GO_0042026 | Biological process | protein refolding |
GO_0007517 | Biological process | muscle organ development |
GO_0002088 | Biological process | lens development in camera-type eye |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0030308 | Biological process | negative regulation of cell growth |
GO_0097512 | Cellular component | cardiac myofibril |
GO_0043197 | Cellular component | dendritic spine |
GO_0030018 | Cellular component | Z disc |
GO_0005739 | Cellular component | mitochondrion |
GO_0043204 | Cellular component | perikaryon |
GO_0097060 | Cellular component | synaptic membrane |
GO_0005764 | Cellular component | lysosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0070062 | Cellular component | extracellular exosome |
GO_0009986 | Cellular component | cell surface |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0030424 | Cellular component | axon |
GO_0031430 | Cellular component | M band |
GO_0032432 | Cellular component | actin filament bundle |
GO_0005634 | Cellular component | nucleus |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0001540 | Molecular function | amyloid-beta binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005212 | Molecular function | structural constituent of eye lens |
GO_0005198 | Molecular function | structural molecule activity |
GO_0051082 | Molecular function | unfolded protein binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CRYAB |
Protein name | Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component) Alpha-crystallin B chain (Alpha(B)-crystallin) Crystallin alpha B (Crystallin, alpha B, isoform CRA_c) Crystallin alpha B |
Synonyms | CRYA2 HSPB5 HEL-S-101 hCG_1730741 |
Description | FUNCTION: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity). . FUNCTION: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. . FUNCTION: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. . |
Accessions | ENST00000527950.5 ENST00000533879.2 A0A140G961 ENST00000526180.6 ENST00000529647.5 E9PJL7 ENST00000528628.5 A0A024R3B9 E9PNH7 E9PS12 C3VMY8 ENST00000528961.6 ENST00000650687.2 ENST00000651164.1 ENST00000227251.7 ENST00000531198.5 E9PRA8 ENST00000616970.5 ENST00000533971.2 ENST00000526167.5 ENST00000533280.6 ENST00000651650.1 ENST00000533475.6 ENST00000527899.6 P02511 ENST00000525823.1 V9HW27 |