PFDN2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	32 studies	32% ± 13%	Explore
endothelial cell	31 studies	37% ± 14%	Explore
B cell	30 studies	24% ± 7%	Explore
natural killer cell	30 studies	25% ± 8%	Explore
macrophage	28 studies	28% ± 11%	Explore
conventional dendritic cell	25 studies	36% ± 16%	Explore
CD4-positive, alpha-beta T cell	25 studies	27% ± 15%	Explore
pericyte	25 studies	34% ± 10%	Explore
smooth muscle cell	24 studies	33% ± 10%	Explore
CD8-positive, alpha-beta T cell	21 studies	29% ± 13%	Explore
T cell	20 studies	24% ± 7%	Explore
basal cell	20 studies	35% ± 16%	Explore
classical monocyte	20 studies	25% ± 12%	Explore
non-classical monocyte	20 studies	29% ± 13%	Explore
mast cell	18 studies	29% ± 12%	Explore
regulatory T cell	18 studies	29% ± 10%	Explore
epithelial cell	17 studies	40% ± 18%	Explore
plasmacytoid dendritic cell	16 studies	34% ± 11%	Explore
monocyte	15 studies	27% ± 8%	Explore
endothelial cell of lymphatic vessel	15 studies	33% ± 12%	Explore
memory B cell	15 studies	22% ± 7%	Explore
naive B cell	14 studies	21% ± 6%	Explore
connective tissue cell	14 studies	35% ± 12%	Explore
dendritic cell	13 studies	39% ± 26%	Explore
mature NK T cell	13 studies	21% ± 5%	Explore
gamma-delta T cell	13 studies	27% ± 15%	Explore
capillary endothelial cell	12 studies	27% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	24% ± 8%	Explore
endothelial cell of vascular tree	11 studies	47% ± 15%	Explore
ciliated cell	11 studies	42% ± 17%	Explore
secretory cell	10 studies	32% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	25% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	23% ± 5%	Explore
myofibroblast cell	10 studies	34% ± 8%	Explore
abnormal cell	10 studies	33% ± 15%	Explore
endothelial cell of artery	10 studies	32% ± 8%	Explore
vein endothelial cell	10 studies	33% ± 12%	Explore
mucosal invariant T cell	10 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	27% ± 8%	Explore
myeloid cell	9 studies	32% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	23% ± 4%	Explore
neuron	8 studies	44% ± 19%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	26% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	30% ± 12%	Explore
leukocyte	7 studies	29% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	29% ± 10%	Explore
progenitor cell	7 studies	29% ± 14%	Explore
plasma cell	7 studies	36% ± 11%	Explore
alveolar macrophage	6 studies	29% ± 9%	Explore
kidney loop of Henle epithelial cell	6 studies	24% ± 3%	Explore
glutamatergic neuron	6 studies	32% ± 17%	Explore
precursor B cell	6 studies	32% ± 12%	Explore
innate lymphoid cell	6 studies	23% ± 5%	Explore
T follicular helper cell	6 studies	22% ± 2%	Explore
type I pneumocyte	5 studies	29% ± 13%	Explore
hematopoietic precursor cell	5 studies	39% ± 25%	Explore
plasmablast	5 studies	44% ± 18%	Explore
mononuclear phagocyte	5 studies	38% ± 14%	Explore
epithelial cell of proximal tubule	5 studies	25% ± 7%	Explore
oligodendrocyte	5 studies	27% ± 8%	Explore
enteroendocrine cell	5 studies	34% ± 16%	Explore
type II pneumocyte	5 studies	33% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	28% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	29% ± 11%	Explore
GABAergic neuron	5 studies	27% ± 12%	Explore
goblet cell	5 studies	26% ± 11%	Explore
pancreatic A cell	4 studies	55% ± 11%	Explore
type B pancreatic cell	4 studies	40% ± 13%	Explore
exhausted T cell	4 studies	35% ± 8%	Explore
renal alpha-intercalated cell	4 studies	37% ± 9%	Explore
erythroblast	4 studies	35% ± 20%	Explore
hematopoietic stem cell	4 studies	27% ± 12%	Explore
club cell	4 studies	37% ± 8%	Explore
immature B cell	4 studies	24% ± 7%	Explore
mesothelial cell	4 studies	29% ± 11%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	36% ± 8%	Explore
deuterosomal cell	3 studies	19% ± 2%	Explore
ionocyte	3 studies	31% ± 12%	Explore
precursor cell	3 studies	41% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	42% ± 6%	Explore
neural crest cell	3 studies	37% ± 1%	Explore
retinal bipolar neuron	3 studies	39% ± 15%	Explore
retinal ganglion cell	3 studies	59% ± 25%	Explore
extravillous trophoblast	3 studies	44% ± 5%	Explore
placental villous trophoblast	3 studies	49% ± 4%	Explore
lymphocyte	3 studies	39% ± 9%	Explore
brush cell	3 studies	36% ± 18%	Explore
neuroendocrine cell	3 studies	42% ± 12%	Explore
pro-B cell	3 studies	32% ± 4%	Explore
amacrine cell	3 studies	46% ± 17%	Explore
retina horizontal cell	3 studies	32% ± 17%	Explore
retinal cone cell	3 studies	49% ± 15%	Explore
retinal rod cell	3 studies	31% ± 10%	Explore
microglial cell	3 studies	27% ± 6%	Explore
serous secreting cell	3 studies	24% ± 3%	Explore
germinal center B cell	3 studies	25% ± 3%	Explore
intermediate monocyte	3 studies	40% ± 19%	Explore
granulocyte	3 studies	29% ± 6%	Explore
oligodendrocyte precursor cell	3 studies	32% ± 7%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	47% ± 19%	Explore
intestinal crypt stem cell	3 studies	24% ± 5%	Explore
erythrocyte	3 studies	41% ± 19%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 15%	Explore
transit amplifying cell	3 studies	22% ± 1%	Explore
keratinocyte	3 studies	42% ± 25%	Explore
T-helper 17 cell	3 studies	38% ± 24%	Explore
interneuron	3 studies	25% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	18% ± 3%	Explore
double negative thymocyte	3 studies	37% ± 20%	Explore
progenitor cell of mammary luminal epithelium	3 studies	23% ± 3%	Explore
hepatocyte	3 studies	42% ± 21%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	32% ± 13%	Explore
peripheral blood	14 studies	26% ± 9%	Explore
brain	11 studies	26% ± 9%	Explore
kidney	8 studies	26% ± 5%	Explore
intestine	7 studies	27% ± 12%	Explore
eye	6 studies	28% ± 11%	Explore
uterus	5 studies	34% ± 18%	Explore
lymph node	5 studies	30% ± 14%	Explore
liver	5 studies	31% ± 20%	Explore
pancreas	4 studies	45% ± 13%	Explore
prostate	4 studies	37% ± 14%	Explore
breast	4 studies	34% ± 7%	Explore
placenta	3 studies	41% ± 2%	Explore
bone marrow	3 studies	22% ± 5%	Explore
adrenal gland	3 studies	23% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1855.35	258 / 258	100%	300.25	230 / 230
ovary	100%	1426.55	180 / 180	100%	214.34	430 / 430
uterus	100%	1524.78	170 / 170	100%	426.26	459 / 459
brain	100%	2761.32	2641 / 2642	100%	242.99	705 / 705
skin	100%	1639.07	1805 / 1809	100%	369.25	472 / 472
liver	100%	1377.64	225 / 226	100%	260.35	406 / 406
thymus	100%	1299.26	650 / 653	100%	242.11	605 / 605
esophagus	100%	1511.76	1445 / 1445	99%	201.76	182 / 183
lung	100%	1753.28	576 / 578	99%	297.39	1148 / 1155
intestine	100%	1408.25	966 / 966	99%	253.29	521 / 527
prostate	100%	1400.97	244 / 245	99%	209.47	498 / 502
kidney	100%	1773.22	89 / 89	99%	145.79	890 / 901
stomach	99%	1040.80	357 / 359	99%	218.78	284 / 286
bladder	100%	1594.90	21 / 21	99%	402.63	497 / 504
breast	100%	1771.50	459 / 459	98%	277.95	1101 / 1118
pancreas	95%	612.60	311 / 328	99%	284.39	177 / 178
adipose	100%	2001.18	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	228.11	80 / 80
lymph node	0%	0	0 / 0	100%	369.37	29 / 29
spleen	100%	1344.81	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	267.07	45 / 45
ureter	0%	0	0 / 0	100%	397.53	1 / 1
muscle	100%	2590.55	802 / 803	0%	0	0 / 0
blood vessel	100%	1625.42	1332 / 1335	0%	0	0 / 0
heart	98%	1486.79	848 / 861	0%	0	0 / 0
peripheral blood	78%	1025.91	720 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006457	Biological process	protein folding
GO_0051495	Biological process	positive regulation of cytoskeleton organization
GO_0050821	Biological process	protein stabilization
GO_0061077	Biological process	chaperone-mediated protein folding
GO_1905907	Biological process	negative regulation of amyloid fibril formation
GO_0101031	Cellular component	protein folding chaperone complex
GO_0005829	Cellular component	cytosol
GO_0016272	Cellular component	prefoldin complex
GO_1990062	Cellular component	RPAP3/R2TP/prefoldin-like complex
GO_0005737	Cellular component	cytoplasm
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0044183	Molecular function	protein folding chaperone
GO_0051082	Molecular function	unfolded protein binding
GO_0001540	Molecular function	amyloid-beta binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PFDN2
Protein name	Prefoldin subunit 2 Prefoldin subunit 2 (cDNA, FLJ96845, Homo sapiens prefoldin 2 (PFDN2), mRNA)
Synonyms	PFD2 HSPC231 hCG_1995291
Description	FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. . FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. .
Accessions	ENST00000368010.4 Q9UHV9 B1AQP2

PFDN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review