VBP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	11 studies	20% ± 5%	Explore
endothelial cell	9 studies	25% ± 10%	Explore
fibroblast	9 studies	24% ± 9%	Explore
CD8-positive, alpha-beta T cell	9 studies	20% ± 3%	Explore
CD4-positive, alpha-beta T cell	8 studies	22% ± 4%	Explore
smooth muscle cell	8 studies	18% ± 4%	Explore
pericyte	7 studies	21% ± 6%	Explore
T cell	6 studies	22% ± 4%	Explore
regulatory T cell	6 studies	20% ± 3%	Explore
plasmacytoid dendritic cell	6 studies	21% ± 7%	Explore
connective tissue cell	5 studies	25% ± 7%	Explore
erythroblast	5 studies	36% ± 24%	Explore
epithelial cell	5 studies	38% ± 16%	Explore
erythrocyte	5 studies	32% ± 18%	Explore
basal cell	5 studies	25% ± 12%	Explore
conventional dendritic cell	4 studies	33% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	18% ± 1%	Explore
myofibroblast cell	4 studies	22% ± 1%	Explore
ciliated cell	4 studies	26% ± 8%	Explore
neuron	4 studies	34% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 4%	Explore
plasmablast	3 studies	47% ± 13%	Explore
non-classical monocyte	3 studies	19% ± 2%	Explore
neural crest cell	3 studies	21% ± 5%	Explore
retinal ganglion cell	3 studies	55% ± 27%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	18% ± 1%	Explore
precursor B cell	3 studies	29% ± 9%	Explore
pro-B cell	3 studies	21% ± 3%	Explore
amacrine cell	3 studies	42% ± 18%	Explore
astrocyte	3 studies	27% ± 13%	Explore
retina horizontal cell	3 studies	32% ± 14%	Explore
retinal cone cell	3 studies	48% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
glutamatergic neuron	3 studies	25% ± 6%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 9%	Explore
goblet cell	3 studies	21% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 4%	Explore
gamma-delta T cell	3 studies	31% ± 20%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	6 studies	24% ± 7%	Explore
eye	5 studies	27% ± 13%	Explore
brain	4 studies	22% ± 4%	Explore
peripheral blood	3 studies	22% ± 3%	Explore
liver	3 studies	40% ± 28%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3186.51	2642 / 2642	100%	149.02	705 / 705
esophagus	100%	1702.29	1445 / 1445	100%	71.26	183 / 183
ovary	100%	1553.29	180 / 180	100%	57.67	430 / 430
uterus	100%	1559.55	170 / 170	100%	103.83	459 / 459
breast	100%	1703.14	459 / 459	100%	93.25	1115 / 1118
prostate	100%	1662.36	245 / 245	100%	83.38	500 / 502
lung	99%	1682.73	575 / 578	100%	89.53	1155 / 1155
stomach	100%	1295.57	359 / 359	99%	70.13	284 / 286
bladder	100%	1699.00	21 / 21	99%	87.03	500 / 504
thymus	100%	1577.74	652 / 653	99%	70.64	601 / 605
intestine	100%	1740.51	966 / 966	99%	78.70	522 / 527
adrenal gland	100%	1786.78	258 / 258	98%	84.26	226 / 230
kidney	100%	1907.06	89 / 89	98%	53.63	885 / 901
pancreas	97%	818.30	319 / 328	99%	55.73	176 / 178
liver	97%	842.88	220 / 226	99%	44.48	400 / 406
skin	99%	1644.50	1799 / 1809	96%	71.59	451 / 472
lymph node	0%	0	0 / 0	100%	93.40	29 / 29
muscle	100%	3584.99	803 / 803	0%	0	0 / 0
spleen	100%	1507.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	99.51	45 / 45
ureter	0%	0	0 / 0	100%	32.96	1 / 1
adipose	100%	1706.56	1202 / 1204	0%	0	0 / 0
blood vessel	100%	1646.05	1332 / 1335	0%	0	0 / 0
heart	97%	2244.57	834 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	91%	36.47	73 / 80
peripheral blood	78%	1481.23	722 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007017	Biological process	microtubule-based process
GO_0006457	Biological process	protein folding
GO_0007021	Biological process	tubulin complex assembly
GO_0061077	Biological process	chaperone-mediated protein folding
GO_1905907	Biological process	negative regulation of amyloid fibril formation
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005829	Cellular component	cytosol
GO_0016272	Cellular component	prefoldin complex
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0051082	Molecular function	unfolded protein binding
GO_0001540	Molecular function	amyloid-beta binding
GO_0005515	Molecular function	protein binding
GO_0015631	Molecular function	tubulin binding

IV. Literature review

[source]

Gene name	VBP1
Protein name	Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1) Vpr Binding Protein 1 Prefoldin subunit 3
Synonyms	hCG_17616 PFDN3
Description	FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. . FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. .
Accessions	Q86TP3 Q6FH24 ENST00000625964.2 [P61758-2] P61758 ENST00000535916.5 [P61758-2] ENST00000286428.7 [P61758-1]

VBP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review