GO_0005102 | OmnibusX

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	APOA1-ABCA1	APOA1_HUMAN - ABCA1_HUMAN	Ligand-Receptor	Signaling by Apolipoprotein
2	APOA1-AMN+CUBN	APOA1_HUMAN -	Ligand-Receptor	Signaling by Apolipoprotein
3	APOA1-TREM2+TYROBP	APOA1_HUMAN -	Ligand-Receptor	Signaling by Apolipoprotein
4	APOA2-TREM2+TYROBP	APOA2_HUMAN -	Ligand-Receptor	Signaling by Apolipoprotein
5	APOE-TREM2+TYROBP	APOE_HUMAN -	Ligand-Receptor	Signaling by Apolipoprotein
6	APP-TREM2+TYROBP	A4_HUMAN -	Ligand-Receptor	Signaling by Amyloid-beta precursor protein
7	ARTN-GFRA1+RET	ARTN_HUMAN -	Ligand-Receptor	Signaling by RET receptors
8	ARTN-GFRA3+RET	ARTN_HUMAN -	Ligand-Receptor	Signaling by RET receptors
9	CD58-CD2	LFA3_HUMAN - CD2_HUMAN	Ligand-Receptor
10	CLCF1-CNTFR+IL6ST+LIFR	CLCF1_HUMAN -	Ligand-Receptor
11	CLU-TREM2+TYROBP	CLUS_HUMAN -	Ligand-Receptor
12	CRTAM-CADM1	CRTAM_HUMAN - CADM1_HUMAN	Adhesion-Adhesion
13	CXCL10-DPP4	CXL10_HUMAN - DPP4_HUMAN	Ligand-Receptor	Signaling by Chemokines
14	CXCL12-DPP4	SDF1_HUMAN - DPP4_HUMAN	Ligand-Receptor	Signaling by Chemokines
15	F2-F2R	THRB_HUMAN - PAR1_HUMAN	Ligand-Receptor	Adhesion by Prothrombin
16	GDNF-GFRA1+RET	GDNF_HUMAN -	Ligand-Receptor
17	LRRC4B-PTPRD	LRC4B_HUMAN - PTPRD_HUMAN	Ligand-Receptor	Signaling by Leucine Rich Repeat And Fibronectin
18	MICA-HCST+KLRK1	MICA_HUMAN -	Ligand-Receptor
19	MICB-HCST+KLRK1	MICB_HUMAN -	Ligand-Receptor
20	PTPRC-CD22	PTPRC_HUMAN - CD22_HUMAN	Receptor-Receptor
21	PTPRD-IL1RAPL1	PTPRD_HUMAN - IRPL1_HUMAN	Ligand-Receptor
22	RSPO1-FZD8+LRP6	RSPO1_HUMAN -	Ligand-Receptor	Signaling by R-spondin
23	RSPO1-KREMEN1+LRP6	RSPO1_HUMAN -	Ligand-Receptor	Signaling by R-spondin
24	SEMA4D-CD72	SEM4D_HUMAN - CD72_HUMAN	Ligand-Receptor	Signaling by Semaphorin
25	SEMA4D-PTPRC	SEM4D_HUMAN - PTPRC_HUMAN	Ligand-Receptor	Signaling by Semaphorin
26	WNT3A-FZD10+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
27	WNT3A-FZD1+LRP5	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
28	WNT3A-FZD1+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
29	WNT3A-FZD2+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
30	WNT3A-FZD3+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
31	WNT3A-FZD4+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
32	WNT3A-FZD5+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
33	WNT3A-FZD6+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
34	WNT3A-FZD7+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
35	WNT3A-FZD8+LRP5	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
36	WNT3A-FZD8+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
37	WNT3A-FZD8+RYK	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
38	WNT3A-FZD9+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
39	WNT5B-FZD10+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
40	WNT5B-FZD1+LRP5	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
41	WNT5B-FZD1+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
42	WNT5B-FZD2+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
43	WNT5B-FZD3+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
44	WNT5B-FZD4+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
45	WNT5B-FZD5+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
46	WNT5B-FZD6+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
47	WNT5B-FZD7+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
48	WNT5B-FZD8+LRP5	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
49	WNT5B-FZD8+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
50	WNT5B-FZD9+LRP6	WNT5B_HUMAN -	Ligand-Receptor	Signaling by WNT
51	WNT7A-FZD10+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
52	WNT7A-FZD1+LRP5	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
53	WNT7A-FZD1+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
54	WNT7A-FZD2+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
55	WNT7A-FZD3+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
56	WNT7A-FZD4+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
57	WNT7A-FZD5+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
58	WNT7A-FZD6+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
59	WNT7A-FZD7+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
60	WNT7A-FZD8+LRP5	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
61	WNT7A-FZD8+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
62	WNT7A-FZD9+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT

Name	signaling receptor binding
ID	GO_0005102
collection_id	Molecular function
Description	Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Related synonym	receptor-associated protein activity
Comment	Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'.
External URL
Genes	NPPB BTNL9 CNPY4 IGFBP2 AKAP9 BEX3 MSN TNFSF8 EDN3 GLMN MT-RNR2 DIAPH2 TNFSF12 CALCA EFNA1 CYTL1 CD72 IFNL1 BTN1A1 VTCN1 C1QL1 CXCL10 PTK6 PDZK1 AMN IFNL2 RAB8B SRC abeta-40-oligomer_human ADAM10 WIPI1 MYO1C DPP4 GCG NRXN1 IZUMO1R EGFL8 PTPRC AGRP KNG1 CSNK2B BTN2A3P FN1 ERMAP PDZK1P1 A0A0G2JPB7 ANKRD13C GLG1 HNF4A LOC102723996 LTA ABCA12 PLXNC1 BAG6 SIX3 HILPDA LILRA4 STRAP MOG PLA2G2C TESPA1 NRIP1 LAMA1 LCN1 HAP1 DNAJB11 FCN2 SYNE1 BTN3A2 ANGPTL1 AMH REN JAK2 ARTN NPPA NPY NRTN LRPAP1 SEMA4D BTNL3 C5 CRH RSPO2 ANGPTL6 NHERF2 HLA-G THPO APOA2 HSPA1A APP FYN PTPRD PARK7 LBP CD22 PLA2G1B ANG BTN3A1 CLU MCHR1 LAMA3 SNX17 IGFBP1 HLA-C SYK NHERF4 APOF IFNL4 LCK HLA-A ASIP ITPRID2 TNFSF10 EGFL7 HGF NTN3 TGFB2 FGR ARPP19 ALCAM NHERF1 APOE ICOSLG CADM1 SSTR3 FGF20 NXPH2 RACK1 F2R ANGPT2 POMC DVL3 IGFL3 LRIG2 IAPP MAG SELPLG SMARCD1 TLR6 CRIPTO CCL2 il-27_human BTN3A3 PLG BMP3 PECR ANGPTL5 NXPH4 RSPO1 TAC3 OSTN FCN3 ZDHHC17 IGFBP4 CD2 ADM F2 HSPA1B GIPC1 IGFL1 FGA APOL2 RARA TRAK2 LHB TNFSF13B BTNL2 SCT PICK1 TNFSF4 F7 CX3CL1 PIK3AP1 A2M PLAUR CTNND1 SERPINE1 AR NPFF SRI MBL2 TNFSF13 TIGIT STAT3 BOK ANGPTL2 LRP6 GFRA3 ARRB2 BEX1 abeta-42-oligomer_human RIPK2 BMP2 GDNF BTN2A2 PEX14 WNT7A HLA-F HLA-E TNFSF14 LAMA2 RASA1 FRK IGFL4 CCL17 NXPH1 CRTAM MAP7 RARRES2 ERBIN HRG NPVF TNFSF15 PTPA LRRC4B GSK3A LYN C3 BTNL10P KCNA5 FYB1 LPL CCL13 ZAP70 LGI1 CASK MSTN FZD1 PLAT TYROBP WNT5B IGFL2 TLR4 MICA CNPY3 SEMA3G GBA1 PSPN CNTFR abeta-40-42-oligomer_human HLA-B TNFSF9 FCN1 PDPN PKD2 BANK1 PCSK1N CAV1 DMTN BEX2 VWDE CHRNA10 SLC6A3 GSTM2 EDA BEX5 SCP2 HLA-H PRTN3 NMU SRPX2 ERBB2 LPA F2RL1 CCL15 SMARCD3 FGG DDX54 GAS6 TRIM24 CXCL1 TRPC1 IL1RAPL1 APLN PIK3IP1 IZUMO1 MPP1 IL27 CD160 BTNL8 ADCYAP1 HJV HCK CDH5 ABCA1 CD276 CD58 GJA1 LIF EPHB2 IDUA CAPRIN2 NCK1 UTS2 STX1B P2RX4 BTN2A1 MTSS1 HCST HFE TMED1 RSPO3 GFRA1 MICB TRAF3IP2 INSL4 LEPROT HHLA2 ANXA1 FLT3LG GLA CLCF1 ANO1 SLC39A1 YES1 SERPINE2 SRMS IL17RA IFNL3 BLK ENSA IL17RC FASLG WNT3A PDGFRB FKBP1B APOA1 FZD8 DIAPH1 SCYL2 ADIPOQ ITPRID1 RND1 TRDN LTB NXPH3 GUSB P2RX7 NPPC PANX1 ICAM3 INHA LAMA4 GRP INSL3 CXCL12 TNFSF18 CTNNB1 FGL1 IGFBP6 FGB NTF3 AVP NRG2

signaling receptor binding

I. Involved cell-cell interactions

II. Literature review