I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 26% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 26% ± 10% |
Insufficient scRNA-seq data for expression of FKBP1B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 98% | 191.19 | 640 / 653 | 91% | 2.78 | 550 / 605 |
| brain | 98% | 1003.55 | 2595 / 2642 | 89% | 4.18 | 629 / 705 |
| prostate | 97% | 198.60 | 237 / 245 | 90% | 5.82 | 454 / 502 |
| esophagus | 92% | 143.90 | 1332 / 1445 | 93% | 4.52 | 171 / 183 |
| lung | 99% | 293.65 | 573 / 578 | 85% | 3.59 | 981 / 1155 |
| ovary | 86% | 115.29 | 154 / 180 | 96% | 5.17 | 413 / 430 |
| pancreas | 81% | 111.36 | 265 / 328 | 98% | 8.04 | 175 / 178 |
| uterus | 94% | 136.48 | 159 / 170 | 82% | 4.28 | 375 / 459 |
| stomach | 97% | 296.70 | 349 / 359 | 78% | 3.94 | 222 / 286 |
| skin | 91% | 133.69 | 1649 / 1809 | 75% | 3.13 | 352 / 472 |
| kidney | 94% | 196.75 | 84 / 89 | 67% | 2.30 | 602 / 901 |
| intestine | 91% | 149.97 | 883 / 966 | 68% | 2.75 | 360 / 527 |
| bladder | 81% | 125.95 | 17 / 21 | 77% | 4.13 | 387 / 504 |
| breast | 90% | 130.70 | 412 / 459 | 67% | 1.63 | 746 / 1118 |
| adrenal gland | 79% | 101.67 | 205 / 258 | 73% | 8.59 | 169 / 230 |
| liver | 58% | 95.78 | 130 / 226 | 65% | 4.94 | 263 / 406 |
| adipose | 86% | 118.36 | 1041 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 85% | 131.66 | 1140 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 80% | 1.94 | 36 / 45 |
| eye | 0% | 0 | 0 / 0 | 66% | 1.97 | 53 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 1.28 | 19 / 29 |
| peripheral blood | 55% | 77.56 | 513 / 929 | 0% | 0 | 0 / 0 |
| spleen | 54% | 54.52 | 130 / 241 | 0% | 0 | 0 / 0 |
| heart | 53% | 56.45 | 453 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 1.23 | 11 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042542 | Biological process | response to hydrogen peroxide |
| GO_0006939 | Biological process | smooth muscle contraction |
| GO_0051480 | Biological process | regulation of cytosolic calcium ion concentration |
| GO_0022417 | Biological process | protein maturation by protein folding |
| GO_0019722 | Biological process | calcium-mediated signaling |
| GO_0042098 | Biological process | T cell proliferation |
| GO_0010459 | Biological process | negative regulation of heart rate |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0033197 | Biological process | response to vitamin E |
| GO_0035773 | Biological process | insulin secretion involved in cellular response to glucose stimulus |
| GO_0010881 | Biological process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| GO_0051775 | Biological process | response to redox state |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0006458 | Biological process | 'de novo' protein folding |
| GO_0050849 | Biological process | negative regulation of calcium-mediated signaling |
| GO_0051284 | Biological process | positive regulation of sequestering of calcium ion |
| GO_0048680 | Biological process | positive regulation of axon regeneration |
| GO_0042026 | Biological process | protein refolding |
| GO_0010880 | Biological process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| GO_0051280 | Biological process | negative regulation of release of sequestered calcium ion into cytosol |
| GO_0061179 | Biological process | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
| GO_0000413 | Biological process | protein peptidyl-prolyl isomerization |
| GO_0019227 | Biological process | neuronal action potential propagation |
| GO_0016020 | Cellular component | membrane |
| GO_0030018 | Cellular component | Z disc |
| GO_0005829 | Cellular component | cytosol |
| GO_0034704 | Cellular component | calcium channel complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0033017 | Cellular component | sarcoplasmic reticulum membrane |
| GO_0003755 | Molecular function | peptidyl-prolyl cis-trans isomerase activity |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0016247 | Molecular function | channel regulator activity |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0019855 | Molecular function | calcium channel inhibitor activity |
| GO_0005219 | Molecular function | ryanodine-sensitive calcium-release channel activity |
| GO_0005528 | Molecular function | FK506 binding |
| GO_0030551 | Molecular function | cyclic nucleotide binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | FKBP1B |
| Protein name | FK506 binding protein 1B, 12.6 kDa, isoform CRA_c (FKBP prolyl isomerase 1B) Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12) FKBP prolyl isomerase 1B peptidylprolyl isomerase (EC 5.2.1.8) |
| Synonyms | FKBP9 OTK4 hCG_20938 FKBP12.6 FKBP1L |
| Description | FUNCTION: Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. . FUNCTION: Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. . |
| Accessions | G5E9U6 ENST00000421839.1 F8W6G9 ENST00000380991.8 [P68106-2] H7C0Y3 ENST00000452109.1 ENST00000438630.5 ENST00000380986.9 [P68106-1] P68106 |
