Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 25 studies | 29% ± 14% | |
non-classical monocyte | 21 studies | 37% ± 12% | |
classical monocyte | 19 studies | 24% ± 8% | |
B cell | 17 studies | 23% ± 6% | |
monocyte | 16 studies | 29% ± 9% | |
plasmacytoid dendritic cell | 12 studies | 30% ± 9% | |
myeloid cell | 12 studies | 28% ± 12% | |
microglial cell | 11 studies | 39% ± 16% | |
memory B cell | 9 studies | 19% ± 3% | |
naive B cell | 8 studies | 21% ± 3% | |
natural killer cell | 7 studies | 18% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 6 studies | 17% ± 1% | |
neutrophil | 5 studies | 19% ± 2% | |
precursor B cell | 5 studies | 35% ± 12% | |
dendritic cell | 5 studies | 21% ± 8% | |
pro-B cell | 4 studies | 32% ± 5% | |
mononuclear phagocyte | 4 studies | 27% ± 8% | |
alveolar macrophage | 4 studies | 28% ± 11% | |
conventional dendritic cell | 3 studies | 28% ± 10% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 19% ± 1% | |
immature B cell | 3 studies | 20% ± 3% | |
tissue-resident macrophage | 3 studies | 24% ± 10% | |
germinal center B cell | 3 studies | 25% ± 4% | |
hepatocyte | 3 studies | 39% ± 27% | |
abnormal cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 28% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 5852.30 | 226 / 226 | 99% | 59.51 | 401 / 406 |
pancreas | 100% | 1960.88 | 328 / 328 | 91% | 38.20 | 162 / 178 |
lung | 99% | 1632.48 | 574 / 578 | 89% | 19.50 | 1028 / 1155 |
kidney | 96% | 879.51 | 85 / 89 | 92% | 39.37 | 828 / 901 |
breast | 84% | 486.13 | 386 / 459 | 85% | 14.33 | 952 / 1118 |
thymus | 91% | 512.68 | 593 / 653 | 78% | 9.71 | 472 / 605 |
ovary | 88% | 543.99 | 158 / 180 | 67% | 7.66 | 286 / 430 |
intestine | 68% | 691.50 | 657 / 966 | 86% | 19.69 | 452 / 527 |
prostate | 63% | 294.67 | 154 / 245 | 83% | 11.27 | 419 / 502 |
stomach | 47% | 201.07 | 167 / 359 | 90% | 24.05 | 257 / 286 |
adrenal gland | 71% | 363.18 | 184 / 258 | 45% | 6.52 | 104 / 230 |
brain | 32% | 190.89 | 852 / 2642 | 80% | 12.81 | 564 / 705 |
bladder | 57% | 262.90 | 12 / 21 | 53% | 10.14 | 267 / 504 |
esophagus | 28% | 119.13 | 407 / 1445 | 81% | 18.68 | 149 / 183 |
lymph node | 0% | 0 | 0 / 0 | 100% | 122.38 | 29 / 29 |
peripheral blood | 100% | 9424.28 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 7207.68 | 241 / 241 | 0% | 0 | 0 / 0 |
skin | 30% | 119.66 | 548 / 1809 | 68% | 14.93 | 321 / 472 |
adipose | 95% | 823.31 | 1149 / 1204 | 0% | 0 | 0 / 0 |
uterus | 23% | 77.95 | 39 / 170 | 55% | 7.65 | 252 / 459 |
tonsil | 0% | 0 | 0 / 0 | 78% | 13.54 | 35 / 45 |
blood vessel | 54% | 403.28 | 716 / 1335 | 0% | 0 | 0 / 0 |
heart | 30% | 121.77 | 257 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 19% | 1.64 | 15 / 80 |
muscle | 2% | 6.64 | 19 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0034134 | Biological process | toll-like receptor 2 signaling pathway |
GO_0050727 | Biological process | regulation of inflammatory response |
GO_0034154 | Biological process | toll-like receptor 7 signaling pathway |
GO_0034142 | Biological process | toll-like receptor 4 signaling pathway |
GO_0034162 | Biological process | toll-like receptor 9 signaling pathway |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0036312 | Molecular function | phosphatidylinositol 3-kinase regulatory subunit binding |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0005515 | Molecular function | protein binding |
GO_0042802 | Molecular function | identical protein binding |
Gene name | PIK3AP1 |
Protein name | Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) |
Synonyms | BCAP |
Description | FUNCTION: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL. . |
Accessions | ENST00000339364.10 [Q6ZUJ8-1] Q6ZUJ8 ENST00000371110.6 [Q6ZUJ8-2] ENST00000371109.3 [Q6ZUJ8-3] |